Publications by authors named "Thomas Floss"

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Controlling mitochondrial membrane architecture via MIC60 determines viral replication to promote anti-viral immunity.
Ichiro Katahira, Nina Liebrand, Michal Gorzkiewicz, Niklas Paul Klahm, Džiuljeta Abromavičiūtė, Thomas Floss

Cell Rep· July 2025

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The homeostatic effects of the RE-1 silencing transcription factor on cortical networks are altered under ictogenic conditions in the mouse.
Carmela Vitale, Giulia Natali, Maria Sabina Cerullo, Thomas Floss, Caterina Michetti

Acta Physiol (Oxf)· June 2024

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Restoring vision in adult amblyopia by enhancing plasticity through deletion of the transcriptional repressor REST.
Dmytro Shmal, Giulia Mantero, Thomas Floss, Fabio Benfenati, José Fernando Maya-Vetencourt

iScience· April 2024

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Conditional knockout of REST/NRSF in excitatory neurons reduces seizure susceptibility to chemical kindling.
Giulia Natali, Caterina Michetti, Alicja Krawczun-Rygmaczewska, Thomas Floss, Fabrizia Cesca

Front Cell Neurosci· November 2023

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Neuron-restrictive silencer factor/repressor element 1-silencing transcription factor (NRSF/REST) controls spatial K buffering in primary cortical astrocytes.
Eleonora Centonze, Antonella Marte, Martina Albini, Anna Rocchi, Fabrizia Cesca, Thomas Floss

J Neurochem· June 2023

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Correction: Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.
Federica Buffolo, Valentina Petrosino, Martina Albini, Matteo Moschetta, Federico Carlini, Thomas Floss

Cell Death Dis· May 2023

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REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons.
Anna Rocchi, Emanuele Carminati, Antonio De Fusco, Jagoda Aleksandra Kowalska, Thomas Floss

Aging Cell· October 2021

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Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.
Federica Buffolo, Valentina Petrosino, Martina Albini, Matteo Moschetta, Federico Carlini, Thomas Floss

Cell Death Dis· February 2021

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TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons.
Miriam A Vogt, Zahra Ehsaei, Philip Knuckles, Adrian Higginbottom, Michaela S Helmbrecht, Thomas Floss

Sci Rep· May 2018

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Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice.
Anke Wittmann, Marcus O W Grimm, Harry Scherthan, Marion Horsch, Johannes Beckers, Thomas Floss

PLoS One· June 2017

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Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
Donghong Zhang, Bingruo Wu, Ping Wang, Yidong Wang, Pengfei Lu, Thomas Floss

Nucleic Acids Res· April 2017

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The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence.
Richard Graveline, Katarzyna Marcinkiewicz, Seyun Choi, Marilène Paquet, Wolfgang Wurst, Thomas Floss

Mol Cell Biol· March 2017

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Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model.
Evangelia Vartholomaiou, Marta Madon-Simon, Stéphane Hagmann, Guillaume Mühlebach, Wolfgang Wurst, Thomas Floss

Oncotarget· March 2017

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The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Tamilla Nechiporuk, James McGann, Karin Mullendorff, Jenny Hsieh, Wolfgang Wurst, Thomas Floss

Elife· January 2016

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HIV-1 replication in human immune cells is independent of TAR DNA binding protein 43 (TDP-43) expression.
Julia Nehls, Herwig Koppensteiner, Ruth Brack-Werner, Thomas Floss, Michael Schindler

PLoS One· December 2015

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MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.
Lore Becker, Eva Kling, Evelyn Schiller, Ramona Zeh, Anja Schrewe, Thomas Floss

PLoS One· November 2015

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MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention.
Christin Tischner, Annette Hofer, Veronika Wulff, Joanna Stepek, Iulia Dumitru, Thomas Floss

Hum Mol Genet· April 2015

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Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions.
Mark Mellett, Paola Atzei, Ronan Bergin, Alan Horgan, Thomas Floss

Nat Commun· March 2015

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Mga is essential for the survival of pluripotent cells during peri-implantation development.
Andrew J Washkowitz, Caroline Schall, Kun Zhang, Wolfgang Wurst, Thomas Floss

Development· January 2015

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HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.
Iain M Dykes, Kelly Lammerts van Bueren, Rebekah J Ashmore, Thomas Floss, Wolfgang Wurst

Circ Res· June 2014

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Reply to Jawaid et al.: mitochondrial dysfunction and decrease in body weight of transgenic knock-in mouse model for TDP-43: the question of glucose?
Thomas Floss

J Biol Chem· June 2014

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Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Carola Stribl, Aladin Samara, Dietrich Trümbach, Regina Peis, Manuela Neumann, Thomas Floss

J Biol Chem· April 2014

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Highly efficient targeted mutagenesis in mice using TALENs.
Sudeepta Kumar Panda, Benedikt Wefers, Oskar Ortiz, Thomas Floss, Bettina Schmid

Genetics· November 2013

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Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia.
Mark Mellett, Paola Atzei, Alan Horgan, Emily Hams, Thomas Floss

Nat Commun· February 2013

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Response to Brosch et al.
Jussi Pihlajamäki, Carles Lerin, Dorota Kaminska, Sari Venesmaa, Paula Itkonen, Thomas Floss

Cell Metab· March 2012

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