Publications by authors named "Thomas Gaj"

Claim this Profile
A
A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD.
Tristan X McCallister, Colin K W Lim, Mayuri Singh, Sijia Zhang, Najah S Ahsan, Thomas Gaj

Nat Commun· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SPLICER: a highly efficient base editing toolbox that enables in vivo therapeutic exon skipping.
Angelo Miskalis, Shraddha Shirguppe, Jackson Winter, Gianna Elias, Devyani Swami, Thomas Gaj

Nat Commun· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vivo CRISPR base editing for treatment of Huntington's disease.
Shraddha Shirguppe, Michael Gapinske, Devyani Swami, Nicholas Gosstola, Pankaj Acharya, Thomas Gaj

bioRxiv· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
SPLICER: A Highly Efficient Base Editing Toolbox That Enables Therapeutic Exon Skipping.
Angelo Miskalis, Shraddha Shirguppe, Jackson Winter, Gianna Elias, Devyani Swami, Thomas Gaj

bioRxiv· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD.
Tristan X McCallister, Colin K W Lim, William M Terpstra, M Alejandra Zeballos C, Sijia Zhang, Thomas Gaj

bioRxiv· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins.
M Alejandra Zeballos C, Hayden J Moore, Tyler J Smith, Jackson E Powell, Najah S Ahsan, Thomas Gaj

Nat Commun· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins.
M Alejandra Zeballos C, Hayden J Moore, Tyler J Smith, Jackson E Powell, Najah S Ahsan, Thomas Gaj

bioRxiv· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Statistical analysis of shoreline change reveals erosion and baseline are increasing off the northern Tamil Nadu Coasts of India.
German Amali Jacintha Thomas, Radhika Rajasree Santha Ravindranath, Sriganesh Jeyagopal, Suman Thodhal Yoganandham

Environ Monit Assess· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Delivering Base Editors In Vivo by Adeno-Associated Virus Vectors.
Colin K W Lim, Angelo J Miskalis, Pablo Perez-Pinera, Thomas Gaj

Methods Mol Biol· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CRISPR base editing of cis-regulatory elements enables the perturbation of neurodegeneration-linked genes.
Colin K W Lim, Tristan X McCallister, Christian Saporito-Magriña, Garrett D McPheron, Ramya Krishnan, Thomas Gaj

Mol Ther· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeted gene silencing in the nervous system with CRISPR-Cas13.
Jackson E Powell, Colin K W Lim, Ramya Krishnan, Tristan X McCallister, Christian Saporito-Magriña, Thomas Gaj

Sci Adv· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Next-Generation CRISPR Technologies and Their Applications in Gene and Cell Therapy.
M Alejandra Zeballos C, Thomas Gaj

Trends Biotechnol· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Treatment of a Mouse Model of ALS by In Vivo Base Editing.
Colin K W Lim, Michael Gapinske, Alexandra K Brooks, Wendy S Woods, Jackson E Powell, Thomas Gaj

Mol Ther· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model.
Freja K Ekman, David S Ojala, Maroof M Adil, Paola A Lopez, David V Schaffer, Thomas Gaj

Mol Ther Nucleic Acids· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Manufacturing and Delivering Genome-Editing Proteins.
Jia Liu, Ya-Jun Liang, Pei-Ling Ren, Thomas Gaj

Methods Mol Biol· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The continuously evolving CRISPR barcoding toolbox.
Thomas Gaj, Pablo Perez-Pinera

Genome Biol· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Innovations in CRISPR technology.
Alexandra K Brooks, Thomas Gaj

Curr Opin Biotechnol· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model.
Maroof M Adil, Thomas Gaj, Antara T Rao, Rishikesh U Kulkarni, Christina M Fuentes

Stem Cell Reports· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Hypothalamic Switch for REM and Non-REM Sleep.
Kai-Siang Chen, Min Xu, Zhe Zhang, Wei-Cheng Chang, Thomas Gaj

Neuron· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vivo genome editing improves motor function and extends survival in a mouse model of ALS.
Thomas Gaj, David S Ojala, Freja K Ekman, Leah C Byrne, Prajit Limsirichai

Sci Adv· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery.
Thomas Gaj, Brett T Staahl, Gonçalo M C Rodrigues, Prajit Limsirichai, Freja K Ekman

Nucleic Acids Res· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System.
Gonçalo M C Rodrigues, Thomas Gaj, Maroof M Adil, Joyce Wahba, Antara T Rao

Stem Cell Reports· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-Editing Technologies: Principles and Applications.
Thomas Gaj, Shannon J Sirk, Sai-Lan Shui, Jia Liu

Cold Spring Harb Perspect Biol· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Adeno-Associated Virus-Mediated Delivery of CRISPR-Cas Systems for Genome Engineering in Mammalian Cells.
Thomas Gaj, David V Schaffer

Cold Spring Harb Protoc· November 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons.
D Gowanlock R Tervo, Bum-Yeol Hwang, Sarada Viswanathan, Thomas Gaj, Maria Lavzin

Neuron· October 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis