Publications by authors named "Thomas M Suchyna"

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Investigating the interaction of Grammostola rosea venom peptides and model lipid bilayers with solid-state NMR and electron microscopy techniques.
Geraldine Polido, Xiangyan Shi, Dian Xu, Chengchen Guo, Rich Thai, Thomas M Suchyna

Biochim Biophys Acta Biomembr· January 2019

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GsMTx4-D provides protection to the D2.mdx mouse.
Christopher W Ward, Frederick Sachs, Ernest D Bush, Thomas M Suchyna

Neuromuscul Disord· October 2018

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Piezo channels and GsMTx4: Two milestones in our understanding of excitatory mechanosensitive channels and their role in pathology.
Thomas M Suchyna

Prog Biophys Mol Biol· November 2017

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GsMTx4: Mechanism of Inhibiting Mechanosensitive Ion Channels.
Radhakrishnan Gnanasambandam, Chiranjib Ghatak, Anthony Yasmann, Kazuhisa Nishizawa, Frederick Sachs, Thomas M Suchyna

Biophys J· January 2017

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GsMTx4-D is a cardioprotectant against myocardial infarction during ischemia and reperfusion.
Jinli Wang, Yina Ma, Frederick Sachs, Ji Li, Thomas M Suchyna

J Mol Cell Cardiol· September 2016

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Human PIEZO1 Ion Channel Functions as a Split Protein.
Chilman Bae, Thomas M Suchyna, Lynn Ziegler, Frederick Sachs, Philip A Gottlieb

PLoS One· July 2016

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Effects of Lys to Glu mutations in GsMTx4 on membrane binding, peptide orientation, and self-association propensity, as analyzed by molecular dynamics simulations.
Kazuhisa Nishizawa, Manami Nishizawa, Radhakrishnan Gnanasambandam, Frederick Sachs, Sergei I Sukharev, Thomas M Suchyna

Biochim Biophys Acta· November 2015

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Properties and Mechanism of the Mechanosensitive Ion Channel Inhibitor GsMTx4, a Therapeutic Peptide Derived from Tarantula Venom.
Philip A Gottlieb, Thomas M Suchyna, Frederick Sachs

Curr Top Membr· September 2014

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Caveolae regulation of mechanosensitive channel function in myotubes.
Haixia Huang, Chilman Bae, Frederick Sachs, Thomas M Suchyna

PLoS One· April 2014

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Real Time FRET Based Detection of Mechanical Stress in Cytoskeletal and Extracellular Matrix Proteins.
Fanjie Meng, Thomas M Suchyna, Elena Lazakovitch, Richard M Gronostajski, Frederick Sachs

Cell Mol Bioeng· June 2011

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Stretch induced endothelin-1 secretion by adult rat astrocytes involves calcium influx via stretch-activated ion channels (SACs).
Lyle W Ostrow, Thomas M Suchyna, Frederick Sachs

Biochem Biophys Res Commun· June 2011

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Biophysics and structure of the patch and the gigaseal.
Thomas M Suchyna, Vladislav S Markin, Frederick Sachs

Biophys J· August 2009

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A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ.
Fanjie Meng, Thomas M Suchyna, Frederick Sachs

FEBS J· June 2008

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Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes.
Thomas M Suchyna, Frederick Sachs

J Physiol· May 2007

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Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology.
Charles L Bowman, Philip A Gottlieb, Thomas M Suchyna, Yolanda K Murphy, Frederick Sachs

Toxicon· February 2007

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Effects of stretch-activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse.
Ella W Yeung, Nicholas P Whitehead, Thomas M Suchyna, Philip A Gottlieb, Frederick Sachs

J Physiol· January 2005

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Mechanosensitive ion channels as drug targets.
Philip A Gottlieb, Thomas M Suchyna, Lyle W Ostrow, Frederick Sachs

Curr Drug Targets CNS Neurol Disord· August 2004

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Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.
Thomas M Suchyna, Sonya E Tape, Roger E Koeppe, Olaf S Andersen, Frederick Sachs

Nature· July 2004

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Dynamic regulation of mechanosensitive channels: capacitance used to monitor patch tension in real time.
Thomas M Suchyna, Steven R Besch, Frederick Sachs

Phys Biol· June 2004

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Solution structure of peptide toxins that block mechanosensitive ion channels.
Robert E Oswald, Thomas M Suchyna, Robert McFeeters, Philip Gottlieb, Frederick Sachs

J Biol Chem· September 2002

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