Publications by authors named "Thomas McFall"

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Pancreatic Cells Are Resistant to KRASQ61L Expression due to Hyperactive ERK/MAPK Signaling and Apoptosis Induction.
Rachel A Burge, Lucas Bialousow, Thomas McFall, Logan Bamonte, Grayson Johnson

Cancer Res Commun· October 2025

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Mutant and Wild-type RAS Crosstalk and Stoichiometric Deficiencies are Determinants of Sensitivity to Targeted Therapies in KRASG12R Pancreatic Ductal Adenocarcinoma.
Mandana Kamgar, G Aaron Hobbs, Raven Davidson, Daniel Dorbin, Juliannie Herrera, Thomas McFall

Cancer Res· October 2025

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Mathematical modeling suggests 14-3-3 proteins modulate RAF paradoxical activation.
Gaurav Mendiratta, Kodye Abbott, Yao-Cheng Li, Jingting Yu, Peter Carlip, Thomas McFall

PLoS Comput Biol· August 2025

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Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for Pancreatic Ductal Adenocarcinoma.
Ben George, Olga Kudryashova, Andrey Kravets, Samih Thalji, Subramaniam Malarkannan, Thomas McFall

Gastroenterology· May 2024

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Chemotherapy-free treatment targeting fusions and driver mutations in wild-type pancreatic ductal adenocarcinoma, a case series.
Maahum Mehdi, Aniko Szabo, Aditya Shreenivas, James P Thomas, Susan Tsai, Thomas McFall

Ther Adv Med Oncol· May 2024

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Co-targeting KRAS G12C and EGFR reduces both mutant and wild-type RAS-GTP.
Thomas McFall, Michael Trogdon, Anita C Guizar, John F Langenheim, Laura Sisk-Hackworth

NPJ Precis Oncol· November 2022

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Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach.
Thomas McFall, Edward C Stites

Cell Rep· December 2021

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KRAS-Mutated, Estrogen Receptor-Positive Low-Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery.
Shumei Kato, Thomas McFall, Kenta Takahashi, Kasey Bamel, Sadakatsu Ikeda

Oncologist· April 2021

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Discernment between candidate mechanisms for KRAS G13D colorectal cancer sensitivity to EGFR inhibitors.
Thomas McFall, Noah K Schomburg, Kent L Rossman, Edward C Stites

Cell Commun Signal· November 2020

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A mechanism for the response of KRAS expressing colorectal cancers to EGFR inhibitors.
Thomas McFall, Edward Cooper Stites

Mol Cell Oncol· January 2020

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A systems mechanism for KRAS mutant allele-specific responses to targeted therapy.
Thomas McFall, Jolene K Diedrich, Meron Mengistu, Stacy L Littlechild, Kendra V Paskvan

Sci Signal· September 2019

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Strategy for Tumor-Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer.
Rayna Rosati, Lisa Polin, Charles Ducker, Jing Li, Xun Bao, Thomas McFall

Clin Cancer Res· December 2018

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Chronic p27 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor.
Mugdha Patki, Thomas McFall, Rayna Rosati, Yanfang Huang, Agnes Malysa

Sci Rep· October 2018

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Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen.
Thomas McFall, Brooke McKnight, Rayna Rosati, Seongho Kim, Yanfang Huang

J Biol Chem· January 2018

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The Amino-terminal Domain of the Androgen Receptor Co-opts Extracellular Signal-regulated Kinase (ERK) Docking Sites in ELK1 Protein to Induce Sustained Gene Activation That Supports Prostate Cancer Cell Growth.
Rayna Rosati, Mugdha Patki, Venkatesh Chari, Selvakumar Dakshnamurthy, Thomas McFall

J Biol Chem· December 2016

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Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells.
Rayna Rosati, Bailing Chen, Mugdha Patki, Thomas McFall, Siyu Ou

Mol Pharmacol· September 2016

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Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges.
Thomas McFall, Mugdha Patki, Rayna Rosati, Manohar Ratnam

Oncotarget· October 2015

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Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed.
Mugdha Patki, Shirish Gadgeel, Yanfang Huang, Thomas McFall, Anthony F Shields

J Thorac Oncol· April 2014

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