Publications by authors named "Thomas Misgeld"

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Complement C4d Informs the Differential Diagnosis of Inflammatory Demyelinating CNS Diseases.
Carolin Landt, Friederike Held, Konstantina Kolotourou, Mihaela Guranda, Aigli G Vakrakou, Thomas Misgeld

Neurol Neuroimmunol Neuroinflamm· March 2026

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A fully iPS-cell-derived 3D model of the human blood-brain barrier for exploring neurovascular disease mechanisms and therapeutic interventions.
Judit González-Gallego, Katalin Todorov-Völgyi, Stephan A Müller, Sophie Antesberger, Mihail Ivilinov Todorov, Thomas Misgeld

Nat Neurosci· December 2025

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The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis.
Marcel S Woo, Johannes Brand, Lukas C Bal, Manuela Moritz, Mark Walkenhorst, Thomas Misgeld

Cell· October 2025

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Neuronal compartmentalization results in "impoverished" axonal mitochondria.
Adrian Marti Pastor, Liam S C Lewis, Stephan Müller, Pedro Guedes-Dias, Lorena Olifiers, Thomas Misgeld

bioRxiv· October 2025

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The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis.
Marcel S Woo, Johannes Brand, Lukas C Bal, Manuela Moritz, Mark Walkenhorst, Thomas Misgeld

Cell· August 2025

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Polyglutamylation of microtubules drives neuronal remodeling.
Antoneta Gavoci, Anxhela Zhiti, Michaela Rusková, Maria M Magiera, Mengzhe Wang, Thomas Misgeld

Nat Commun· June 2025

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Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time Förster Resonance Energy Transfer.
Igor Khalin, Nagappanpillai Adarsh, Martina Schifferer, Antonia Wehn, Valeria J Boide-Trujillo, Thomas Misgeld

ACS Nano· April 2025

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Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons.
Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva, Thomas Misgeld

Elife· February 2025

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Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation.
Benedikt S Saller, Svenja Wöhrle, Larissa Fischer, Clara Dufossez, Isabella L Ingerl, Thomas Misgeld

Immunity· January 2025

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Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex.
Georg Kislinger, Gunar Fabig, Antonia Wehn, Lucia Rodriguez, Hanyi Jiang, Thomas Misgeld

Elife· August 2024

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Brain imaging turned inside out.
Shahrzad Askari, Thomas Misgeld

Nat Biotechnol· July 2024

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Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain.
Marina Herwerth, Matthias T Wyss, Nicola B Schmid, Jacqueline Condrau, Luca Ravotto, Thomas Misgeld

bioRxiv· May 2024

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Fluorogenic Chemical Probes for Wash-free Imaging of Cell Membrane Damage in Ferroptosis, Necrosis, and Axon Injury.
Philipp Mauker, Daniela Beckmann, Annabel Kitowski, Constanze Heise, Chantal Wientjens, Thomas Misgeld

J Am Chem Soc· April 2024

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Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy.
Mihai Ancău, Goutam Kumar Tanti, Vicki Marie Butenschoen, Jens Gempt, Igor Yakushev, Thomas Misgeld

EBioMedicine· February 2024

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Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.
Yi-Heng Tai, Daniel Engels, Giuseppe Locatelli, Ioanna Emmanouilidis, Caroline Fecher, Thomas Misgeld

Nat Metab· August 2023

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Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice.
Natalia Prudente de Mello, Caroline Fecher, Adrian Marti Pastor, Fabiana Perocchi, Thomas Misgeld

Nat Protoc· July 2023

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Neurons on tape: Automated Tape Collecting Ultramicrotomy-mediated volume EM for targeting neuropathology.
Georg Kislinger, Cornelia Niemann, Lucia Rodriguez, Hanyi Jiang, Maryam K Fard, Thomas Misgeld

Methods Cell Biol· July 2023

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Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
Karin A Ziegler, Andrea Ahles, Anne Dueck, Dena Esfandyari, Pauline Pichler, Thomas Misgeld

Science· July 2023

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Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.
Aleksandra Mezydlo, Nils Treiber, Emily Melisa Ullrich Gavilanes, Katharina Eichenseer, Mihai Ancău, Thomas Misgeld

Neuron· June 2023

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P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica : P2R Inhibitors Prevent Autoantibody Injury.
Sudhakar Reddy Kalluri, Rajneesh Srivastava, Selin Kenet, Goutam K Tanti, Klaus Dornmair, Thomas Misgeld

Neurotherapeutics· September 2022

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Ketogenic diet uncovers differential metabolic plasticity of brain cells.
Tim Düking, Lena Spieth, Stefan A Berghoff, Lars Piepkorn, Annika M Schmidke, Thomas Misgeld

Sci Adv· September 2022

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Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis.
Friederike Liesche-Starnecker, Martina Schifferer, Jürgen Schlegel, Yannik Vollmuth, Dennis Rubbenstroth, Thomas Misgeld

Acta Neuropathol· August 2022

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A new form of axonal pathology in a spinal model of neuromyelitis optica.
Marina Herwerth, Selin Kenet, Martina Schifferer, Anne Winkler, Melanie Weber, Thomas Misgeld

Brain· June 2022

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Size-Selective Transfer of Lipid Nanoparticle-Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury.
Igor Khalin, Nagappanpillai Adarsh, Martina Schifferer, Antonia Wehn, Bernhard Groschup, Thomas Misgeld

Small· May 2022

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A less painful transfer of power.
Martin Kerschensteiner, Thomas Misgeld

Neuron· February 2022

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