Publications by authors named "Thomas P Flagg"

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Transcriptional reprogramming in SMA mouse hearts reveals signatures of early heart failure and dysregulated calcium signaling.
Cecelia C Mangione, Andrew Frank, Clifton L Dalgard, Barrington G Burnett, Thomas P Flagg

Hum Mol Genet· June 2025

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Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation.
Narayanan Puthillathu Vasudevan, Dharmendra K Soni, John R Moffett, Jishnu K S Krishnan, Abhilash P Appu, Thomas P Flagg

Int J Mol Sci· February 2023

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Considerations for Optimizing Warfighter Psychological Health with a Research-Based Flavonoid Approach: A Review.
Tanisha L Currie, Marguerite M Engler, Victor Krauthamer, Jonathan M Scott, Patricia A Deuster, Thomas P Flagg

Nutrients· February 2023

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Methadone Blockade of Cardiac Inward Rectifier K Current Augments Membrane Instability and Amplifies U Waves on Surface ECGs: A Translational Study.
Michael G Klein, Mori J Krantz, Naheed Fatima, Ashlie Watters, Dayan Colon-Sanchez, Thomas P Flagg

J Am Heart Assoc· June 2022

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The Effects of Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells: A Potential Cardioprotective and Neuroprotective Mechanism.
Tanisha L Currie, Marguerite M Engler, Cara H Olsen, Victor Krauthamer, Jonathan M Scott, Thomas P Flagg

Molecules· April 2022

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Novel cholesterol-dependent regulation of cardiac K subunit expression revealed using histone deacetylase inhibitors.
Robert Geiger, Naheed Fatima, James F Schooley, Jeremy T Smyth, Mark C Haigney, Thomas P Flagg

Physiol Rep· January 2021

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Rapid Assessment of Proarrhythmic Potential Using Human iPSC-Derived Cardiomyocytes.
Robert M Geiger, Michael G Klein, Naheed Fatima, Robert E Goldstein, Mori J Krantz, Thomas P Flagg

JACC Clin Electrophysiol· December 2020

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SMN-deficiency disrupts SERCA2 expression and intracellular Ca signaling in cardiomyocytes from SMA mice and patient-derived iPSCs.
Guzal Khayrullina, Kasey E Moritz, James F Schooley, Naheed Fatima, Coralie Viollet, Thomas P Flagg

Skelet Muscle· May 2020

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Dangerous Needle Stick.
Mori J Krantz, Thomas P Flagg, Mark C P Haigney

Circulation· April 2020

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Hemodynamic Effects of Late Sodium Current Inhibitors in a Swine Model of Heart Failure.
Robert E Goldstein, Michael G Klein, Sean P Ouimet, Matie Shou, Maureen N Hood, Thomas P Flagg

J Card Fail· October 2019

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Role of suppression of the inward rectifier current in terminal action potential repolarization in the failing heart.
Michael G Klein, Matie Shou, Jayna Stohlman, Soroosh Solhjoo, Myles Haigney, Thomas P Flagg

Heart Rhythm· August 2017

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Avoiding the chopping block in curricular reform: reimagining physiology laboratories in the era of integrated medical curricula.
Thomas P Flagg, Stephen Rothwell, Brian Neubauer

Adv Physiol Educ· June 2017

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Reply: Labeling and Drug Safety of Loperamide: Time for a Proactive Approach?
Mark C Haigney, Michael G Klein, Thomas P Flagg, Naheed Fatima, Philip S Mehler

JACC Clin Electrophysiol· April 2017

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Potent Inhibition of hERG Channels by the Over-the-Counter Antidiarrheal Agent Loperamide.
Michael G Klein, Mark C P Haigney, Philip S Mehler, Naheed Fatima, Thomas P Flagg

JACC Clin Electrophysiol· December 2016

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Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis.
Naheed Fatima, Devin C Cohen, Gauthaman Sukumar, Tristan M Sissung, James F Schooley, Thomas P Flagg

Front Pharmacol· August 2015

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Acetate transiently inhibits myocardial contraction by increasing mitochondrial calcium uptake.
James F Schooley, Aryan M A Namboodiri, Rachel T Cox, Rolf Bünger, Thomas P Flagg

BMC Physiol· December 2014

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Electrocardiographic studies of romidepsin demonstrate its safety and identify a potential role for K(ATP) channel.
Anne M Noonan, Robin A Eisch, David J Liewehr, Tristan M Sissung, David J Venzon, Thomas P Flagg

Clin Cancer Res· June 2013

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Promoter DNA methylation regulates murine SUR1 (Abcc8) and SUR2 (Abcc9) expression in HL-1 cardiomyocytes.
Naheed Fatima, James F Schooley, Willliam C Claycomb, Thomas P Flagg

PLoS One· November 2012

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"Cardiac KATP": a family of ion channels.
Thomas P Flagg, Colin G Nichols

Circ Arrhythm Electrophysiol· December 2011

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Muscle KATP channels: recent insights to energy sensing and myoprotection.
Thomas P Flagg, Decha Enkvetchakul, Joseph C Koster, Colin G Nichols

Physiol Rev· July 2010

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Palmitate attenuates myocardial contractility through augmentation of repolarizing Kv currents.
Todd E Haim, Wei Wang, Thomas P Flagg, Michael A Tones, Anthony Bahinski

J Mol Cell Cardiol· February 2010

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Cardiac sarcolemmal K(ATP) channels: Latest twists in a questing tale!
Haixia Zhang, Thomas P Flagg, Colin G Nichols

J Mol Cell Cardiol· January 2010

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Differential K(ATP) channel pharmacology in intact mouse heart.
Alexey V Glukhov, Thomas P Flagg, Vadim V Fedorov, Igor R Efimov, Colin G Nichols

J Mol Cell Cardiol· January 2010

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Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice.
Paul J Schaeffer, Jaime Desantiago, John Yang, Thomas P Flagg, Attila Kovacs

Am J Physiol Heart Circ Physiol· October 2009

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Ca2+-independent alterations in diastolic sarcomere length and relaxation kinetics in a mouse model of lipotoxic diabetic cardiomyopathy.
Thomas P Flagg, Olivier Cazorla, Maria S Remedi, Todd E Haim, Michael A Tones

Circ Res· January 2009

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