Publications by authors named "Thomas Pickel"

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Differentiation of n-1 Positional Isomers in Antisense Oligonucleotides with Orthogonal LCMS Methods.
Zifan Li, Xiaoqing Kong, Xiao Zhou, Li Xiao, Rasika Phansalkar, Thomas C Pickel

J Am Soc Mass Spectrom· August 2025

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Quantitative Determination of Click-Reactive Antisense Oligonucleotide and Its Reactivity in Rat Brains by Hybridization LC-MS/MS to Support Pretargeted PET Imaging.
Di Jiang, Brendon E Cook, Thomas Pickel, Long Yuan

Anal Chem· June 2025

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-Cyclooctene Isomerization Catalyzed by Thiamine Degradation Products in Cell Culture Media.
Cathy A Muste, Thomas C Pickel, Philippe N Bolduc, Emily A Peterson, Chungang Gu

ACS Omega· June 2025

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PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry.
Brendon E Cook, Thomas C Pickel, Sangram Nag, Philippe N Bolduc, Rouaa Beshr

Sci Transl Med· May 2025

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Simplified Oligonucleotide Phosphorus Deprotection Process with Reduced 3-(2-Cyanoethyl) Thymidine Impurities.
Xuan Zhou, Xianglin Shi, Yannick Fillon, Firoz Antia, Thomas Pickel

Nucleic Acid Ther· April 2024

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The Chelate Effect Rationalizes Observed Rate Acceleration and Enantioselectivity in BINOL-Catalyzed Petasis Reactions.
Fredrik Haeffner, Thomas C Pickel, April Hou, Donald G Walker, William F Kiesman

Chemistry· March 2023

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Synthesis, Radiolabeling, and Biological Evaluation of the -Stereoisomers of 1-Amino-3-(fluoro-F)-4-fluorocyclopentane-1-carboxylic Acid as PET Imaging Agents.
Thomas C Pickel, Gouthami Pashikanti, Ronald J Voll, Weiping Yu, Zhaobin Zhang

ACS Pharmacol Transl Sci· June 2021

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Synthesis, Radiolabeling, and Biological Evaluation of the Stereoisomers of 1-Amino-3-Fluoro-4-(fluoro-)Cyclopentane-1-Carboxylic Acid as PET Imaging Agents.
Thomas C Pickel, Ronald J Voll, Weiping Yu, Zhaobin Wang, Jonathon A Nye

J Med Chem· October 2020

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Esterification by Redox Dehydration Using Diselenides as Catalytic Organooxidants.
Thomas C Pickel, Srirama Murthy Akondi, Lanny S Liebeskind

J Org Chem· May 2019

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Aerobic, Diselenide-Catalyzed Redox Dehydration: Amides and Peptides.
Srirama Murthy Akondi, Pavankumar Gangireddy, Thomas C Pickel, Lanny S Liebeskind

Org Lett· February 2018

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Site-selective and stereoselective functionalization of non-activated tertiary C-H bonds.
Kuangbiao Liao, Thomas C Pickel, Vyacheslav Boyarskikh, John Bacsa, Djamaladdin G Musaev

Nature· November 2017

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