Publications by authors named "Thomas R Jackson"

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Lead optimisation of OXS007417: PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia.
Thomas J Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R G Galan, Morgan Jay-Smith, Thomas R Jackson

RSC Med Chem· July 2024

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Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines.
Laia Josa-Culleré, Sébastien R G Galan, Thomas J Cogswell, Thomas R Jackson, Morgan Jay-Smith

Eur J Med Chem· October 2023

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A tubulin binding molecule drives differentiation of acute myeloid leukemia cells.
Thomas R Jackson, Aini Vuorinen, Laia Josa-Culleré, Katrina S Madden, Daniel Conole

iScience· August 2022

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A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells and Shows Antitumor Effects .
Laia Josa-Culleré, Katrina S Madden, Thomas J Cogswell, Thomas R Jackson, Tom S Carter

J Med Chem· November 2021

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Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[][1,4]oxazepin-2(3)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro.
Laia Josa-Culleré, Thomas J Cogswell, Irene Georgiou, Morgan Jay-Smith, Thomas R Jackson

Molecules· November 2021

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The Origin of B-cells: Human Fetal B Cell Development and Implications for the Pathogenesis of Childhood Acute Lymphoblastic Leukemia.
Thomas R Jackson, Rebecca E Ling, Anindita Roy

Front Immunol· October 2021

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DNA methylation of the Oct4A enhancers in embryonal carcinoma cells after etoposide treatment is associated with alternative splicing and altered pluripotency in reversibly senescent cells.
Mikhail Baryshev, Inna Inashkina, Kristine Salmina, Anda Huna, Thomas R Jackson

Cell Cycle· September 2019

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Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide.
Anda Huna, Kristine Salmina, Jekaterina Erenpreisa, Alejandro Vazquez-Martin, Jekabs Krigerts, Thomas R Jackson

Cell Cycle· August 2016

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MultiElec: A MATLAB Based Application for MEA Data Analysis.
Vassilis Georgiadis, Anastasis Stephanou, Paul A Townsend, Thomas R Jackson

PLoS One· March 2016

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Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target.
Bashar Zeidan, Thomas R Jackson, Samantha E T Larkin, Ramsey I Cutress, Gary R Coulton

Oncotarget· August 2015

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The "virgin birth", polyploidy, and the origin of cancer.
Jekaterina Erenpreisa, Kristine Salmina, Anda Huna, Thomas R Jackson, Alejandro Vazquez-Martin

Oncoscience· March 2015

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DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells.
Thomas R Jackson, Kristine Salmina, Anda Huna, Inna Inashkina, Eriks Jankevics

Cell Cycle· February 2013

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Macroautophagy-aided elimination of chromatin: sorting of waste, sorting of fate?
Jekaterina Erenpreisa, Anda Huna, Kristine Salmina, Thomas R Jackson, Mark S Cragg

Autophagy· December 2012

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Study results from the Clinical Trials Network's first 10 years: where do they lead?
Elizabeth A Wells, Andrew J Saxon, Donald A Calsyn, Thomas R Jackson, Dennis M Donovan

J Subst Abuse Treat· June 2010

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Boronate affinity saccharide electrophoresis: a novel carbohydrate analysis tool.
Thomas R Jackson, Jeremy S Springall, Damien Rogalle, Naoko Masumoto, Hung Ching Li

Electrophoresis· November 2008

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China's one-child family policy.
Thomas R Jackson

N Engl J Med· February 2006

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