Publications by authors named "Thomas R Ott"

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AC-260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model.
Stefania Risso Bradley, Jelveh Lameh, Linda Ohrmund, Thomas Son, Abhishek Bajpai, Thomas R Ott

Neuropharmacology· February 2010

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Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists.
Hanna Pettersson, Anne Bülow, Fredrik Ek, Jacob Jensen, Lars K Ottesen, Thomas R Ott

J Med Chem· April 2009

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Structural requirements of transmembrane domain 3 for activation by the M1 muscarinic receptor agonists AC-42, AC-260584, clozapine, and N-desmethylclozapine: evidence for three distinct modes of receptor activation.
Tracy A Spalding, Jian-Nong Ma, Thomas R Ott, Mikael Friberg, Abhishek Bajpai

Mol Pharmacol· December 2006

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The N-terminal domain of CCL21 reconstitutes high affinity binding, G protein activation, and chemotactic activity, to the C-terminal domain of CCL19.
Thomas R Ott, Francisco M Lio, Dennis Olshefski, Xin-Jun Liu, Nicholas Ling, R Scott Struthers

Biochem Biophys Res Commun· September 2006

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Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
Kimberly E Vanover, David M Weiner, Malath Makhay, Isaac Veinbergs, Luis R Gardell, Thomas R Ott, Scott C Harvey

J Pharmacol Exp Ther· May 2006

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Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors.
Ethan S Burstein, Thomas R Ott, Michele Feddock, Jian-Nong Ma, Steve Fuhs

Br J Pharmacol· January 2006

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A high-throughput chemotaxis assay for pharmacological characterization of chemokine receptors: Utilization of U937 monocytic cells.
Thomas R Ott, Anil Pahuja, Francisco M Lio, Monica S Mistry, Molly Gross, R Scott Struthers

J Pharmacol Toxicol Methods· July 2005

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Identification of CC chemokine receptor 7 residues important for receptor activation.
Thomas R Ott, Anil Pahuja, Sarah A Nickolls, David G Alleva, R Scott Struthers

J Biol Chem· October 2004

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A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12.
Kevin Morgan, Darrell Conklin, Adam J Pawson, Robin Sellar, Thomas R Ott

Endocrinology· February 2003

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Two mutations in extracellular loop 2 of the human GnRH receptor convert an antagonist to an agonist.
Thomas R Ott, Brigitte E Troskie, Roger W Roeske, Nicola Illing, Colleen A Flanagan

Mol Endocrinol· May 2002

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