Publications by authors named "Thomas Register"

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PET imaging utility of a novel Aβ-tracking PET radiotracer, [F]FC119S in aged vervet monkeys.
Bhuvanachandra Bhoopal, Brett M Frye, Mack Miller, Avinash Bansode, Krishna K Gollapelli, Thomas C Register

J Transl Med· January 2026

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A phase 2A/B randomized trial of metabolic modulators intranasal insulin and empagliflozin for MCI and early AD.
Jennifer M Erichsen, Thomas C Register, Courtney Sutphen, Da Ma, Sarah A Gaussoin

Alzheimers Dement· October 2025

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Age, glucose tolerance, and cognitive performance in female vervet monkeys.
Brett M Frye, Trinity G Davis, Haiying Chen, Thomas C Register, Suzanne Craft

Geroscience· October 2025

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Evaluation of plasma p-tau217 for detecting amyloid pathology in a heterogeneous community-based cohort.
Marc D Rudolph, Courtney L Sutphen, Thomas C Register, Samuel N Lockhart, Melissa M Rundle

Alzheimers Dement· July 2025

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First-in-human positron emission tomography study of intranasal insulin in aging and MCI.
Kiran K Solingapuram Sai, Jennifer M Erichsen, Krishna K Gollapelli, Ivan Krizan, Mack Miller, Thomas C Register

Alzheimers Dement (N Y)· July 2025

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Differential effects of Mediterranean vs. Western diets on coronary atherosclerosis and peripheral artery transcriptomics.
Aya Jamal Abusheikha, Corbin S C Johnson, Noah Snyder-Mackler, Kip D Zimmerman, Jacob D Negrey, Thomas C Register

Front Nutr· July 2025

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Circulating small extracellular vesicles as blood-based biomarkers of muscle health in aging nonhuman primates.
Shalini Mishra, Ashish Kumar, Yangen He, Yixin Su, Sangeeta Singh, Thomas C Register

Geroscience· June 2025

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Relationship of Alzheimer's Disease and Related Dementias Plasma Biomarkers With Mobility in Cognitively Unimpaired Older Adults.
Atalie C Thompson, Xiaoyan Leng, Michael E Miller, Thomas C Register, Paul J Laurienti

J Gerontol A Biol Sci Med Sci· June 2025

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Effects of Diminished Cerebrospinal Fluid Flow in the Spinal Canal on Amyloid Pathophysiology in Vervet Monkeys.
Jeongchul Kim, Megan E Lipford, Richard A Barcus, Brett M Frye, Hongyu Yuan, Thomas C Register

Res Sq· May 2025

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Mediterranean vs. Western diet effects on the primate cerebral cortical pre-synaptic proteome: Relationships with the transcriptome and multi-system phenotypes.
Eloise Berson, Brett M Frye, Chandresh R Gajera, Geetha Saarunya, Amalia Perna, Thomas C Register

Alzheimers Dement· March 2025

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Plasma and neuroimaging biomarkers of small vessel disease and Alzheimer's disease in a diverse cohort: MESA.
Samuel N Lockhart, Courtney L Sutphen, Jordan Tanley, Fernando Gonzalez-Ortiz, Przemysław R Kac, Thomas C Register

medRxiv· February 2025

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Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.
Bryan J Neth, Kevin Huynh, Corey Giles, Tingting Wang, Natalie A Mellett, Thomas C Register

Commun Med (Lond)· January 2025

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Evaluation of plasma p-tau217 for detecting amyloid pathology in a diverse and heterogeneous community-based cohort.
Marc D Rudolph, Courtney L Sutphen, Thomas C Register, Samuel N Lockhart, Melissa M Rundle

medRxiv· January 2025

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Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation via Hexosamine Biosynthetic Pathway.
Luís F Grilo, Kip D Zimmerman, Sobha Puppala, Jeannie Chan, Hillary F Huber, Thomas C Register

Adv Sci (Weinh)· October 2024

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Carotid ultrasound to identify head and neck cancer survivors with high cardiovascular risk after radiation therapy: rationale and design of a prospective, cross-sectional pilot study.
Ryan T Hughes, Anna C Snavely, Emily V Dressler, Charles H Tegeler, Chandylen L Nightingale, Thomas C Register

Future Oncol· October 2024

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Alzheimer disease-like neuropathologic changes in a geriatric baboon ().
William T Harrison, J Mark Cline, David L Caudell, Hillary F Huber, Carol A Shively, Thomas C Register

J Vet Sci· September 2024

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First Biodistribution Study of [68Ga]Ga-NOTA-Insulin Following Intranasal Administration in Adult Vervet Monkeys.
Kiran Kumar Solingapuram Sai, Jennifer M Erichsen, Krishna K Gollapelli, Ivan Krizan, Mack Miller, Thomas Register

J Alzheimers Dis· August 2024

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Mediterranean diet protects against a neuroinflammatory cortical transcriptome: Associations with brain volumetrics, peripheral inflammation, social isolation, and anxiety in nonhuman primates (Macaca fascicularis).
Brett M Frye, Jacob D Negrey, Corbin S C Johnson, Jeongchul Kim, Richard A Barcus, Thomas C Register

Brain Behav Immun· July 2024

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Female baboon adrenal zona fasciculata and zona reticularis regulatory and functional proteins decrease across the life course.
Hillary Fries Huber, Cun Li, Dongbin Xie, Kenneth G Gerow, Thomas C Register

Geroscience· June 2024

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Associations among plasma, MRI, and amyloid PET biomarkers of Alzheimer's disease and related dementias and the impact of health-related comorbidities in a community-dwelling cohort.
Marc D Rudolph, Courtney L Sutphen, Thomas C Register, Christopher T Whitlow, Kiran K Solingapuram Sai

Alzheimers Dement· June 2024

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Integrated multi-omics analysis of brain aging in female nonhuman primates reveals altered signaling pathways relevant to age-related disorders.
Laura A Cox, Sobha Puppala, Jeannie Chan, Kip D Zimmerman, Zeeshan Hamid, Thomas C Register

Neurobiol Aging· December 2023

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Mediterranean Diet Protects Against a Neuroinflammatory Cortical Transcriptome: Associations with Brain Volumetrics, Peripheral Inflammation, Social Isolation and Anxiety.
Jacob D Negrey, Brett M Frye, Corbin S C Johnson, Jeongchul Kim, Richard A Barcus, Thomas C Register

bioRxiv· November 2023

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Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway.
Luís F Grilo, Kip D Zimmerman, Sobha Puppala, Jeannie Chan, Hillary F Huber, Thomas C Register

bioRxiv· November 2023

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Preliminary PET Imaging of Microtubule-Based PET Radioligand [C]MPC-6827 in a Nonhuman Primate Model of Alzheimer's Disease.
Bhuvanachandra Bhoopal, Krishna Kumar Gollapelli, Naresh Damuka, Mack Miller, Ivan Krizan, Thomas Register

ACS Chem Neurosci· October 2023

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Cross-species comparative analysis of single presynapses.
Eloïse Berson, Chandresh R Gajera, Thanaphong Phongpreecha, Amalia Perna, Syed A Bukhari, Thomas C Register

Sci Rep· August 2023

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