Publications by authors named "Thomas Roche"

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Antifungal Activity of Polyalthic Acid Analogs Against Cryptococcus neoformans Involves Production of Reactive Oxygen Species (ROS) and Disruption of Cell Membrane Integrity.
Thomas A Mennella, Kyung U Hong, Joshua Bojito, Thomas R Roche, Eun-Jung Park

Chem Biodivers· December 2025

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Development of Rogowski probe for internal plasma current measurement in the collisional merging process of field-reversed configurations.
Juri Ogasawara, Tomohiko Asai, Daichi Kobayashi, Taichi Seki, Tsutomu Takahashi, Thomas Roche

Rev Sci Instrum· October 2022

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Effect of moisture content and fuel type on emissions from vegetation using a steady state combustion apparatus.
Priya Garg, Thomas Roche, Matthew Eden, Jacqueline Matz, Jessica M Oakes

Int J Wildland Fire· October 2021

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Crystal structure of the catalytic subunit of bovine pyruvate dehydrogenase phosphatase.
Youzhong Guo, Weihua Qiu, Thomas E Roche, Marvin L Hackert

Acta Crystallogr F Struct Biol Commun· July 2020

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Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex.
Jiansen Jiang, Flavius L Baiesc, Yasuaki Hiromasa, Xuekui Yu, Wong Hoi Hui, Thomas E Roche

Biochemistry· April 2018

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Critical role of specific ions for ligand-induced changes regulating pyruvate dehydrogenase kinase isoform 2.
Yasuaki Hiromasa, Thomas E Roche

Biochemistry· February 2008

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Specific ion influences on self-association of pyruvate dehydrogenase kinase isoform 2 (PDHK2), binding of PDHK2 to the L2 lipoyl domain, and effects of the lipoyl group-binding site inhibitor, Nov3r.
Yasuaki Hiromasa, Xiaohua Yan, Thomas E Roche

Biochemistry· February 2008

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Structures of the human pyruvate dehydrogenase complex cores: a highly conserved catalytic center with flexible N-terminal domains.
Xuekui Yu, Yasuaki Hiromasa, Hua Tsen, James K Stoops, Thomas E Roche

Structure· January 2008

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Ligand-induced effects on pyruvate dehydrogenase kinase isoform 2.
Yasuaki Hiromasa, Liangyan Hu, Thomas E Roche

J Biol Chem· May 2006

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Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands.
Thorsten R Knoechel, Alec D Tucker, Colin M Robinson, Chris Phillips, Wendy Taylor, Thomas E Roche

Biochemistry· January 2006

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Formation of a complex of the catalytic subunit of pyruvate dehydrogenase phosphatase isoform 1 (PDP1c) and the L2 domain forms a Ca2+ binding site and captures PDP1c as a monomer.
Ali Turkan, Yasuaki Hiromasa, Thomas E Roche

Biochemistry· November 2004

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Pyruvate dehydrogenase kinase isoform 2 activity limited and further inhibited by slowing down the rate of dissociation of ADP.
Haiying Bao, Shane A Kasten, Xiaohua Yan, Thomas E Roche

Biochemistry· October 2004

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Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
Haiying Bao, Shane A Kasten, Xiaohua Yan, Yasuaki Hiromasa, Thomas E Roche

Biochemistry· October 2004

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Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components.
Yasuaki Hiromasa, Tetsuro Fujisawa, Yoichi Aso, Thomas E Roche

J Biol Chem· February 2004

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Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis.
Sylvaine F A Bruggraber, Patrick S C Leung, Katsushi Amano, Chao Quan, Mark J Kurth, Thomas E Roche

Gastroenterology· December 2003

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Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase.
Yasuaki Hiromasa, Thomas E Roche

J Biol Chem· September 2003

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Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1.
Thomas E Roche, Yasuaki Hiromasa, Ali Turkan, Xiaoming Gong, Tao Peng

Eur J Biochem· March 2003

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Structural requirements within the lipoyl domain for the Ca2+-dependent binding and activation of pyruvate dehydrogenase phosphatase isoform 1 or its catalytic subunit.
Ali Turkan, Xiaoming Gong, Tao Peng, Thomas E Roche

J Biol Chem· April 2002

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Suitability of MDCK cells grown in a serum-free medium for influenza virus production.
N Kessler, G Thomas-Roche, L Gérentes, M Aymard

Dev Biol Stand· December 1999

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