Publications by authors named "Thomas Rossetti"

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Triazole-based STING inhibitors.
Anju Singh, Leonard Barasa, Leo DeOrsey, Maeve D O'Reilly, Shruti Choudhary, Thomas Rossetti

Bioorg Med Chem· January 2026

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Addition to "Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation".
Shan Sun, Makoto Fushimi, Thomas Rossetti, Navpreet Kaur, Jacob Ferreira

J Chem Inf Model· February 2024

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Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory in mice and is neuroprotective in pigs.
Nicole L Rumian, Carolyn Nicole Brown, Tara B Hendry-Hofer, Thomas Rossetti, James E Orfila

J Biol Chem· May 2023

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Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation.
Shan Sun, Makoto Fushimi, Thomas Rossetti, Navpreet Kaur, Jacob Ferreira

J Chem Inf Model· May 2023

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Corrigendum: Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential.
Thomas Rossetti, Jacob Ferreira, Lubna Ghanem, Hannes Buck, Clemens Steegborn

Front Physiol· March 2023

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On-demand male contraception via acute inhibition of soluble adenylyl cyclase.
Melanie Balbach, Thomas Rossetti, Jacob Ferreira, Lubna Ghanem, Carla Ritagliati

Nat Commun· February 2023

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Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory and is neuroprotective in non-rodents.
Nicole L Rumian, Carolyn Nicole Brown, Tara B Hendry-Hofer, Thomas Rossetti, James E Orfila

bioRxiv· January 2023

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Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.
Michael Miller, Thomas Rossetti, Jacob Ferreira, Lubna Ghanem, Melanie Balbach

J Med Chem· November 2022

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Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential.
Thomas Rossetti, Jacob Ferreira, Lubna Ghanem, Hannes Buck, Clemens Steegborn

Front Physiol· September 2022

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Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.
Melanie Balbach, Lubna Ghanem, Thomas Rossetti, Navpreet Kaur, Carla Ritagliati

Mol Hum Reprod· September 2021

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Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).
Makoto Fushimi, Hannes Buck, Melanie Balbach, Anna Gorovyy, Jacob Ferreira, Thomas Rossetti

ACS Med Chem Lett· August 2021

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