Publications by authors named "Thomas Sayers"

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CD8 T-NK cell crosstalk establishes preemptive immunosurveillance to eliminate antigen-escape tumors.
Roman V Uzhachenko, Salvador González Ochoa, Thanigaivelan Kanagasabai, Harshana Rajakaruna, Menaka C Thounaojam, Thomas J Sayers

Front Immunol· October 2025

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Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma.
E M Kithsiri Wijeratne, Ya-Ming Xu, Manping X Liu, Marielle C Inacio, Alan D Brooks, Thomas J Sayers

J Nat Prod· December 2021

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Divergence in floral scent and morphology, but not thermogenic traits, associated with pollinator shift in two brood-site-mimicking Typhonium (Araceae) species.
Thomas D J Sayers, Kim L Johnson, Martin J Steinbauer, Kevin Farnier, Rebecca E Miller

Ann Bot· August 2021

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Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins.
Poonam Tewary, Alan D Brooks, Ya-Ming Xu, E M Kithsiri Wijeratne, Ashley L Babyak, Thomas J Sayers

Cancer Res· June 2021

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Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs.
Ancy D Nalli, Lauren E Brown, Cheryl L Thomas, Thomas J Sayers, John A Porco

Sci Rep· November 2018

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Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica.
Ya-Ming Xu, E M Kithsiri Wijeratne, Alan D Brooks, Poonam Tewary, Li-Jiang Xuan, Thomas J Sayers

Phytochemistry· August 2018

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Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib.
Xiaofei Wang, Keqiang Chen, Ying Yu, Yi Xiang, Jae Hong Kim, Thomas Sayers

Oncotarget· December 2017

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Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells.
Ya-Ming Xu, E M Kithsiri Wijeratne, Ashley L Babyak, Hanna R Marks, Alan D Brooks, Thomas J Sayers

J Nat Prod· July 2017

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17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.
Ya-Ming Xu, Alan D Brooks, E M Kithsiri Wijeratne, Curtis J Henrich, Poonam Tewary, Thomas J Sayers

J Med Chem· April 2017

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Using natural products to promote caspase-8-dependent cancer cell death.
Poonam Tewary, A A Leslie Gunatilaka, Thomas J Sayers

Cancer Immunol Immunother· February 2017

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Modulatory effects of bortezomib on host immune cell functions.
Samuel Troy Pellom, Duafalia Fred Dudimah, Menaka Chanu Thounaojam, Thomas Joseph Sayers, Anil Shanker

Immunotherapy· August 2016

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Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.
Anil Shanker, Samuel T Pellom, Duafalia F Dudimah, Menaka C Thounaojam, Rachel L de Kluyver, Thomas J Sayers

Cancer Res· December 2015

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NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype.
Erik Ames, Robert J Canter, Steven K Grossenbacher, Stephanie Mac, Mingyi Chen, Thomas J Sayers

J Immunol· October 2015

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Impact of dietary components on NK and Treg cell function for cancer prevention.
Young S Kim, Thomas J Sayers, Nancy H Colburn, John A Milner, Howard A Young

Mol Carcinog· September 2015

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Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells.
Kevin T Sayers, Alan D Brooks, Thomas J Sayers, Oleg Chertov

PLoS One· April 2015

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Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma.
Robert J Canter, Erik Ames, Stephanie Mac, Steven K Grossenbacher, Mingyi Chen, Thomas J Sayers

BMC Cancer· October 2014

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Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy.
Jonathan M Weiss, Jeff J Subleski, Tim Back, Xin Chen, Stephanie K Watkins, Thomas J Sayers

J Immunol· June 2014

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A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.
Lesley A Mathews, Jonathan M Keller, Bonnie L Goodwin, Rajarshi Guha, Paul Shinn, Thomas J Sayers

J Biomol Screen· October 2012

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ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials.
Anatoli M Malyguine, Susan Strobl, Kimberly Dunham, Michael R Shurin, Thomas J Sayers

Cells· May 2012

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Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima.
Emily L Whitson, Han Sun, Cheryl L Thomas, Curtis J Henrich, Thomas J Sayers

J Nat Prod· March 2012

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Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis.
Curtis J Henrich, Cheryl L Thomas, Alan D Brooks, Nancy Lynn Booth, Evan M Lowery, Thomas J Sayers

Apoptosis· January 2012

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Targeting the extrinsic apoptosis signaling pathway for cancer therapy.
Thomas J Sayers

Cancer Immunol Immunother· August 2011

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Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers.
Emily L Whitson, Cheryl L Thomas, Curtis J Henrich, Thomas J Sayers, James B McMahon

J Nat Prod· December 2010

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Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia.
Xin Liu, Lindsay Ryland, Jun Yang, Aijun Liao, Cesar Aliaga, Thomas Joseph Sayers

Blood· November 2010

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New flow cytometric assays for monitoring cell-mediated cytotoxicity.
Liubov Zaritskaya, Michael R Shurin, Thomas J Sayers, Anatoli M Malyguine

Expert Rev Vaccines· June 2010

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