Publications by authors named "Thomas Scriba"

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Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes.
Kate Bridges, Denis Awany, Anele Gela, Temwa-Dango Mwambene, Sherry L Kurtz, Thomas J Scriba

JCI Insight· December 2025

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Comparison of automated and manual mRNA enrichment to automated rRNA depletion for whole-blood RNA-sequencing.
Denis Awany, Helgard Claassen, Nadia Carstens, Simon C Mendelsohn, Mzwandile Erasmus, Thomas J Scriba

Sci Rep· December 2025

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Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study.
Jayne S Sutherland, Gian D van der Spuy, Jane A Shaw, Tracy Richardson, Elisa M Tjon Kon Fat, Thomas J Scriba

Clin Infect Dis· November 2025

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Oral Rinse versus Facemask Capture for Nonsputum Diagnosis of Pulmonary Tuberculosis.
Simon C Mendelsohn, Gabriella T Jackson, Edmund Wessels, Elizabeth Beyers, Suzette Visagie, Thomas J Scriba

Am J Respir Crit Care Med· November 2025

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Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines.
Samuel J Vidal, Ninaad Lasrado, Lisa H Tostanoski, Jayeshbhai Chaudhari, Esther R Mbiwan, Thomas J Scriba

Cell· November 2025

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Single-gene transcripts for subclinical tuberculosis: an individual participant data meta-analysis.
James Greenan-Barrett, Simon C Mendelsohn, Thomas J Scriba, Mahdad Noursadeghi, Rishi K Gupta

Lancet Microbe· November 2025

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Screening for asymptomatic tuberculosis among adults with household exposure to pulmonary tuberculosis: a prospective observational cohort study.
Simon C Mendelsohn, Humphrey Mulenga, Michele Tameris, Tumelo Moloantoa, Stephanus T Malherbe, Thomas J Scriba

Lancet Glob Health· November 2025

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Peptide-driven identification of TCRs reveals dynamics and phenotypes of CD4 T cells in tuberculosis.
Rashmi Tippalagama, Raphael Trevizani, Leila Y Chihab, Ashu Chawla, Kai Fung, Thomas Scriba

J Immunol· November 2025

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Enrichment of a CD4CD8 NK-like cytotoxic Vδ1/3 T cell subset in tuberculosis disease.
Kendall Kearns, Rashmi Tippalagama, Ashu Chawla, Jason Greenbaum, Aruna Dharshan De Silva, Thomas J Scriba

bioRxiv· November 2025

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Asymptomatic Tuberculosis in Children with Household Exposure to Mycobacterium tuberculosis.
Humphrey Mulenga, Justin Shenje, Simon C Mendelsohn, Angelique K K Luabeya, Michele Tameris, Thomas J Scriba

Clin Infect Dis· October 2025

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Mycobacterium tuberculosis-specific blood immune signatures distinguish sarcoidosis from tuberculosis disease.
Leila Y Chihab, Catherine Cheng, Hannah Hillman, Nabeela Khan, Kendall Kearns, Thomas Scriba

J Immunol· October 2025

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Inflammatory Biomarkers of Asymptomatic and Symptomatic Tuberculosis.
Denis Awany, Dominique T Ariefdien, Simon C Mendelsohn, Virginie Rozot, Humphrey Mulenga, Thomas J Scriba

bioRxiv· October 2025

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BCG Vaccination at Birth Shapes the TCR Usage and Functional Profile of MR1T Cells at 9 Weeks of Age.
Dylan Kain, G W McElfresh, Gwendolyn M Swarbrick, Katherine Rott, Gregory Boggy, Thomas J Scriba

bioRxiv· October 2025

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Blood transcriptomic signatures predict poor treatment outcomes in drug-susceptible pulmonary TB in Brazil.
Simon C Mendelsohn, Bruno B Andrade, Mariana Araújo-Pereira, Gustavo C Amorim, Mzwandile Erasmus, Thomas J Scriba

medRxiv· October 2025

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T cell monocyte complexes exhibit distinct immune signatures during infection.
Ningxin Kang, Ashu Chawla, Hannah Hillman, Rashmi Tippalagama, Cheryl Kim, Thomas J Scriba

iScience· September 2025

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Humoral, T cell and immune gene expression responses to SARS-CoV-2 vaccination in a small group of children with previous MIS-C.
Timothy F Spracklen, Jonathan Day, Hamza Van Der Ross, Claire Butters, Ntombi Benede, Thomas J Scriba

Vaccine· August 2025

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Immunogenicity, safety, and efficacy of the vaccine H56:IC31 in reducing the rate of tuberculosis disease recurrence in HIV-negative adults successfully treated for drug-susceptible pulmonary tuberculosis: a double-blind, randomised, placebo-controlled, phase 2b trial.
Álvaro H Borges, Marisa Russell, Dereck Tait, Thomas J Scriba, Elisa Nemes

Lancet Infect Dis· July 2025

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Live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in adults with or without M tuberculosis sensitisation: a single-centre, phase 1b-2a, double-blind, dose-escalation, randomised controlled trial.
Angelique Kany Kany Luabeya, Virginie Rozot, Claire Imbratta, Frances Ratangee, Justin Shenje, Thomas J Scriba

Lancet Glob Health· June 2025

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BCG induced innate immune response heterogeneity and susceptibility to pediatric tuberculosis.
Christine Anterasian, Anele Gela, Temwa-Dango Mwambene, Javeed A Shah, Josh Ivie, Thomas J Scriba

J Immunol· May 2025

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BCG Revaccination for the Prevention of Infection.
Alexander C Schmidt, Lee Fairlie, Elizabeth Hellström, Angelique Luabeya Kany Kany, Keren Middelkoop, Thomas J Scriba

N Engl J Med· May 2025

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Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes.
Kate Bridges, Denis Awany, Anele Gela, Temwa-Dango Mwanbene, Christopher M Sassetti, Thomas J Scriba

bioRxiv· May 2025

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Peptide Driven Identification of TCRs (PDI-TCR) reveals dynamics and phenotypes of CD4 T cells in tuberculosis.
Rashmi Tippalagama, Raphael Trevizani, Leila Y Chihab, Ashu Chawla, Kai Fung, Thomas J Scriba

bioRxiv· May 2025

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Safety, reactogenicity, and immunogenicity of MTBVAC in infants: a phase 2a randomised, double-blind, dose-defining trial in a TB endemic setting.
Michele Tameris, Virginie Rozot, Claire Imbratta, Hennie Geldenhuys, Simon C Mendelsohn, Thomas J Scriba

EBioMedicine· April 2025

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HLA-E/ specific CD4 and CD8 T cells have a memory phenotype in individuals with TB infection.
Linda Voogd, Catherine Riou, Thomas J Scriba, Marjolein van Wolfswinkel, Krista E van Meijgaarden

Front Immunol· January 2025

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Screening for Asymptomatic Tuberculosis among Adults with Household Exposure to a Patient with Pulmonary Tuberculosis.
Simon C Mendelsohn, Humphrey Mulenga, Michele Tameris, Tumelo Moloantoa, Stephanus T Malherbe, Thomas J Scriba

medRxiv· January 2025

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