Publications by authors named "Thomas Silvers"

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High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids.
Thomas S Dexheimer, Nathan P Coussens, Thomas Silvers, Poorva Juneja, Eric Jones

SLAS Discov· December 2025

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RAS Pathway Inhibitors Combined with Targeted Agents Are Active in Patient-Derived Spheroids with Oncogenic KRAS Variants from Multiple Cancer Types.
Zahra Davoudi, Thomas S Dexheimer, Nathan P Coussens, Thomas Silvers, Raymond G Fox

Cancer Res Commun· October 2025

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Polymerase Ѳ inhibitors combinations with approved and investigational agents in patient-derived tumor multi-cell type (mct) spheroids.
Beverly A Teicher, Thomas S Dexheimer, Li Chen, Thomas Silvers, Eric M Jones

Exp Mol Pathol· September 2025

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RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids.
Beverly A Teicher, Thomas S Dexheimer, Thomas Silvers, Nathan P Coussens, Eric Jones

Cancer Chemother Pharmacol· September 2025

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Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids.
Nathan P Coussens, Thomas S Dexheimer, Thomas Silvers, Phillip R Sanchez, Li Chen

SLAS Discov· June 2025

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Targeted therapy combinations with ipatasertib in multi-cell type 3D tumor spheroid models.
Beverly A Teicher, Naoko Takebe, Thomas S Dexheimer, Thomas E Silvers, Nathan P Coussens

Acad Oncol· June 2025

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RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids.
Beverly A Teicher, Thomas S Dexheimer, Thomas Silvers, Nathan P Coussens, Eric Jones

Res Sq· May 2025

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Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids.
Thomas S Dexheimer, Zahra Davoudi, Nathan P Coussens, Thomas Silvers, Joel Morris

SLAS Discov· April 2025

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Combination screen in multi-cell type tumor spheroids reveals interaction between aryl hydrocarbon receptor antagonists and E1 ubiquitin-activating enzyme inhibitor.
Thomas S Dexheimer, Nathan P Coussens, Thomas Silvers, Eric M Jones, Li Chen

SLAS Discov· October 2024

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Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs.
Thomas S Dexheimer, Nathan P Coussens, Thomas Silvers, John Wright, Joel Morris

Cancer Res Commun· August 2023

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Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets.
Julia Krushkal, Thomas Silvers, William C Reinhold, Dmitriy Sonkin, Suleyman Vural

Clin Epigenetics· June 2020

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Exposure time versus cytotoxicity for anticancer agents.
David M Evans, Jianwen Fang, Thomas Silvers, Rene Delosh, Julie Laudeman

Cancer Chemother Pharmacol· August 2019

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Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent.
Beverly A Teicher, Thomas Silvers, Michael Selby, Rene Delosh, Julie Laudeman

Cancer Med· August 2017

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3D Models of the NCI60 Cell Lines for Screening Oncology Compounds.
Mike Selby, Rene Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Thomas Silvers

SLAS Discov· June 2017

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Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer.
Ying Chen, Sandra Catalina Camacho, Thomas R Silvers, Albiruni R A Razak, Nashat Y Gabrail

Clin Cancer Res· March 2017

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Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.
Eric Polley, Mark Kunkel, David Evans, Thomas Silvers, Rene Delosh

J Natl Cancer Inst· October 2016

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Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression.
Beverly A Teicher, Eric Polley, Mark Kunkel, David Evans, Thomas Silvers

Mol Cancer Ther· November 2015

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Osmolyte effects on the self-association of concanavalin A: testing theoretical models.
Thomas R Silvers, Jeffrey K Myers

Biochemistry· December 2013

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Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
Vaibhav Saini, Curtis D Hose, Anne Monks, Kunio Nagashima, Bingnan Han, Thomas E Silvers

PLoS One· February 2013

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A high-throughput fluorescence-anisotropy screen that identifies small molecule inhibitors of the DNA binding of B-ZIP transcription factors.
Vikas Rishi, Timothy Potter, Julie Laudeman, Russel Reinhart, Thomas Silvers

Anal Biochem· May 2005

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