Publications by authors named "Thomas Tarnowski"

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Best Practices and Recommendations for Non-Liquid Matrices Bioanalysis.
Faye Vazvaei-Smith, Wenkui Li, Omar S Barnaby, Sanjeev Bhardwaj, Juyao Dong, Thomas Tarnowski

AAPS J· March 2025

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Plasma Protein Binding Determination for Unstable Ester Prodrugs: Remdesivir and Tenofovir Alafenamide.
Anita Wen, Ann Ran-Ran Qin, Thomas Tarnowski, Kah Hiing John Ling, Haeyoung Zhang

J Pharm Sci· December 2023

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Phase 1 first-in-human study of dalutrafusp alfa, an anti-CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors.
Anthony W Tolcher, Michael Gordon, Kathleen M Mahoney, Anna Seto, Marianna Zavodovskaya, Thomas Tarnowski

J Immunother Cancer· February 2023

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Evaluation of the potential for pharmacokinetic interaction between tirabrutinib and levonorgestrel/ethinyl estradiol in healthy female volunteers.
Ganesh Cherala, Cara Nelson, Ying Guo, Anubhav Mathur, Thomas Tarnowski

Clin Transl Sci· June 2022

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The determination of Sulfobutylether β-Cyclodextrin Sodium (SBECD) by LC-MS/MS and its application in remdesivir pharmacokinetics study for pediatric patients.
Zhengdong Yang, Deqing Xiao, Kah Hiing John Ling, Thomas Tarnowski, Rita Humeniuk

J Pharm Biomed Anal· April 2022

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Assessment of the Effect of Filgotinib on the Pharmacokinetics of Atorvastatin, Pravastatin, and Rosuvastatin in Healthy Adult Participants.
Kacey Anderson, Cara H Nelson, Qi Gong, Muhsen Alani, Thomas Tarnowski

Clin Pharmacol Drug Dev· February 2022

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Semi-Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA.
Amy Meng, Rita Humeniuk, Juliane M Jürgensmeier, Chia-Hsiang Hsueh, Franziska Matzkies, Thomas Tarnowski

Clin Pharmacol Ther· February 2022

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Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.
Deqing Xiao, Kah Hiing John Ling, Thomas Tarnowski, Rita Humeniuk, Polina German

Anal Biochem· March 2021

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An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer.
Deqing Xiao, Kah Hiing John Ling, Thomas Tarnowski, Sophia R Majeed, Polina German

Anal Biochem· March 2020

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The determination of human peripheral blood mononuclear cell counts using a genomic DNA standard and application in tenofovir diphosphate quantitation.
Deqing Xiao, Kah Hiing John Ling, Thomas Tarnowski, Sophia R Majeed, Brian Kearney

Anal Biochem· November 2019

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Quantitation of intracellular triphosphate metabolites of antiretroviral agents in peripheral blood mononuclear cells (PBMCs) and corresponding cell count determinations: review of current methods and challenges.
Deqing Xiao, Kah Hiing John Ling, Joseph Custodio, Sophia R Majeed, Thomas Tarnowski

Expert Opin Drug Metab Toxicol· August 2018

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Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment.
Yan Xin, Jun Kawashima, Winnie Weng, Ellen Kwan, Thomas Tarnowski

J Clin Pharmacol· April 2018

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The Relative Bioavailability, Food Effect, and Drug Interaction With Omeprazole of Momelotinib Tablet Formulation in Healthy Subjects.
Yan Xin, Lixin Shao, Julie Maltzman, Dimitrios Stefanidis, Jeffrey Hemenway, Thomas Tarnowski

Clin Pharmacol Drug Dev· March 2018

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