Publications by authors named "Thomas Upton"

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Awakening not associated with an increased rate of cortisol secretion.
Samantha Klaas, Thomas J Upton, Eder Zavala, Michael Lawton, Sophie Bensing

Proc Biol Sci· January 2025

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Correction: Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device.
Terrie Walker-Smith, Daniel Fudulu, Aravind Ramesh, Karen Sheehan, Julie Madden, Thomas Upton

BMC Res Notes· March 2024

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Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial.
Georgina Russell, Konstantinos Kalafatakis, Claire Durant, Nicola Marchant, Jamini Thakrar, Thomas Upton

J Intern Med· January 2024

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How an appreciation of dynamics has altered our understanding of the HPA axis.
Stafford Lightman, Thomas Upton

Stress· January 2024

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High-resolution daily profiles of tissue adrenal steroids by portable automated collection.
Thomas J Upton, Eder Zavala, Paal Methlie, Olle Kämpe, Stylianos Tsagarakis

Sci Transl Med· June 2023

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An Investigation of Pulse Oximetry Levels During Swallowing in Healthy Adults and in Individuals with Severe and Very Severe Chronic Obstructive Pulmonary Disease.
Salim S Alani, Julie A G Stierwalt, Leonard L LaPointe, Richard J Morris, Allan C Jeong, Thomas D Upton

Semin Speech Lang· November 2022

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Analysis of wearable time series data in endocrine and metabolic research.
Azure D Grant, Thomas J Upton, John R Terry, Benjamin L Smarr, Eder Zavala

Curr Opin Endocr Metab Res· August 2022

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Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device.
Terrie Walker-Smith, Daniel Fudulu, Aravind Ramesh, Karen Sheehan, Julie Madden, Thomas Upton

BMC Res Notes· June 2022

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Modelling the dynamic interaction of systemic inflammation and the hypothalamic-pituitary-adrenal (HPA) axis during and after cardiac surgery.
Daniel Galvis, Eder Zavala, Jamie J Walker, Thomas Upton, Stafford L Lightman

J R Soc Interface· April 2022

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Completing the β,γ-CXY-dNTP Stereochemical Probe Toolkit: Synthetic Access to the dCTP Diastereomers and P and F NMR Correlations with Absolute Configurations.
Pouya Haratipour, Corinne Minard, Maryam Nakhjiri, Amirsoheil Negahbani, Brian T Chamberlain, Thomas G Upton

J Org Chem· November 2020

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Vitamin D supplementation in pregnancy: A word of caution. Familial hypercalcaemia due to disordered vitamin D metabolism.
Christy Macdonald, Thomas Upton, Penny Hunt, Ian Phillips, Martin Kaufmann

Ann Clin Biochem· March 2020

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Localized Induction of Gene Expression in Embryonic Stem Cell Aggregates Using Holographic Optical Tweezers to Create Biochemical Gradients.
Glen R Kirkham, James Ware, Thomas Upton, Stephanie Allen, Kevin M Shakesheff

Regen Eng Transl Med· August 2019

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Corticosteroids in Pediatric Heart Surgery: Myth or Reality.
Daniel P Fudulu, Ben Gibbison, Thomas Upton, Serban C Stoica, Massimo Caputo

Front Pediatr· April 2018

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Measures of behavioral function predict duration of video game play: Utilization of the Video Game Functional Assessment - Revised.
Frank D Buono, Mark D Griffiths, Matthew E Sprong, Daniel P Lloyd, Ryan M Sullivan, Thomas D Upton

J Behav Addict· December 2017

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Precision assembly of complex cellular microenvironments using holographic optical tweezers.
Glen R Kirkham, Emily Britchford, Thomas Upton, James Ware, Graham M Gibson

Sci Rep· February 2015

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Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution.
Gayan Senavirathne, Malgorzata Jaszczur, Paul A Auerbach, Thomas G Upton, Linda Chelico

J Biol Chem· May 2012

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α-Azido bisphosphonates: synthesis and nucleotide analogues.
Brian T Chamberlain, Thomas G Upton, Boris A Kashemirov, Charles E McKenna

J Org Chem· June 2011

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Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid.
G K Surya Prakash, Mikhail Zibinsky, Thomas G Upton, Boris A Kashemirov, Charles E McKenna

Proc Natl Acad Sci U S A· September 2010

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Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues.
Vinod K Batra, Lars C Pedersen, William A Beard, Samuel H Wilson, Boris A Kashemirov, Thomas G Upton

J Am Chem Soc· June 2010

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Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function.
Thomas G Upton, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, G K Surya Prakash

Org Lett· May 2009

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DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state.
Christopher A Sucato, Thomas G Upton, Boris A Kashemirov, Jorge Osuna, Keriann Oertell

Biochemistry· January 2008

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(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta.
Charles E McKenna, Boris A Kashemirov, Thomas G Upton, Vinod K Batra, Myron F Goodman

J Am Chem Soc· December 2007

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Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta.
Christopher A Sucato, Thomas G Upton, Boris A Kashemirov, Vinod K Batra, Václav Martínek

Biochemistry· January 2007

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A deuterated deep-cavity cavitand confirms the importance of C-H...X-R hydrogen bonds in guest binding.
Zachary R Laughrey, Thomas G Upton, Bruce C Gibb

Chem Commun (Camb)· March 2006

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Resorcinarenes as templates: a general strategy for the synthesis of large macrocycles.
Xuehe Li, Thomas G Upton, Corinne L D Gibb, Bruce C Gibb

J Am Chem Soc· January 2003

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