Publications by authors named "Thomas Valerius"

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Antibody-lectin chimeras for glyco-immune checkpoint blockade.
Jessica C Stark, Melissa A Gray, Itziar Ibarlucea-Benitez, Marta Lustig, Annalise Bond, Thomas Valerius

Nat Biotechnol· December 2025

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Complementing CD20 antibodies' effector functions.
Jeanette Leusen, Thomas Valerius

Blood· March 2025

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Engineering of anticancer human immunoglobulin A equipped with albumin for enhanced plasma half-life.
Simone Mester, Chilam Chan, Marta Lustig, Stian Foss, J H Marco Jansen, Thomas Valerius

PNAS Nexus· February 2025

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Allogeneic Hematopoietic Stem Cell Transplantation From a CD36+ Donor in an Immunized Patient With Type I Hereditary CD36 Deficiency.
Nicolas Spath, Philipp Nakov, Sven-Ole Schuster, Daniel Kownatzki-Danger, Dagmar Steppat, Thomas Valerius

Transplantation· December 2024

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Sialylation inhibition improves macrophage mediated tumor cell phagocytosis of breast cancer cells triggered by therapeutic antibodies of different isotypes.
Marta Lustig, Christoph Hahn, Marie Leangen Herigstad, Jan Terje Andersen, Jeanette H W Leusen, Thomas Valerius

Front Oncol· November 2024

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Enhancing Neutrophil Cytotoxicity of a Panel of Clinical EGFR Antibodies by Fc Engineering to IgA3.0.
Chilam Chan, J H Marco Jansen, Ilona S T Hendriks, Ida C van der Peet, Meggy E L Verdonschot, Thomas Valerius

Mol Cancer Ther· September 2024

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Management of chimeric antigen receptor T (CAR-T) cell-associated toxicities.
Torsten Schroeder, Tjark Martens, Lars Fransecky, Thomas Valerius, Natalie Schub

Intensive Care Med· September 2024

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The impact of MICB mismatches in unrelated haematopoietic stem cell transplantation.
Elisa Maria Amann, Sowmya Gowdavally, Chrysanthi Tsamadou, Uwe Platzbecker, Elisa Sala, Thomas Valerius

HLA· June 2024

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Human Tumor-Associated Macrophages and Neutrophils Regulate Antitumor Antibody Efficacy through Lethal and Sublethal Trogocytosis.
Sunil Singhal, Abhishek S Rao, Jason Stadanlick, Kyle Bruns, Neil T Sullivan, Thomas Valerius

Cancer Res· April 2024

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Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria.
Stian Foss, Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Thomas Valerius

Nat Commun· March 2024

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Comparison of fludarabine/melphalan (FluMel) with fludarabine/melphalan/BCNU or thiotepa (FBM/FTM) in patients with AML in first complete remission undergoing allogeneic hematopoietic stem cell transplantation - a registry study on behalf of the EBMT Acute Leukemia Working Party.
Jesús Duque-Afonso, Jürgen Finke, Maud Ngoya, Jacques-Emmanuel Galimard, Charles Craddock, Thomas Valerius

Bone Marrow Transplant· February 2024

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Enhanced potency of immunotherapy against B-cell precursor acute lymphoblastic leukemia by combination of an Fc-engineered CD19 antibody and CD47 blockade.
Denis M Schewe, Fotini Vogiatzi, Ira A Münnich, Tobias Zeller, Roland Windisch, Thomas Valerius

Hemasphere· February 2024

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Unrelated or haploidentical allogeneic hematopoietic cell transplantation in second complete remission for acute myeloid leukemia-Improved outcomes over time: A European Society for Blood and Marrow Transplantation Acute Leukemia Working Party study.
Rama Al Hamed, Maud Ngoya, Jacques-Emmanuel Galimard, Henrik Sengeloev, Tobias Gedde-Dahl, Thomas Valerius

Cancer· September 2023

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Bispecific Complement Engagers for Targeted Complement Activation.
Dennis V Pedersen, Heidi Gytz, Mikael B L Winkler, Alessandra Zarantonello, Niklas Baumann, Thomas Valerius

J Immunol· August 2023

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KIR2DS4 and Its Variant KIR1D in KIR-AA Genotype Donors Showed Differential Survival Impact in Patients with Lymphoid Disease after HLA-Matched Unrelated Hematopoietic Stem Cell Transplantation.
Sowmya Gowdavally, Chrysanthi Tsamadou, Uwe Platzbecker, Elisa Sala, Thomas Valerius

Transplant Cell Ther· July 2023

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IgA antibody immunotherapy targeting GD2 is effective in preclinical neuroblastoma models.
Marjolein C Stip, Mitchell Evers, Maaike Nederend, Chilam Chan, Karli R Reiding, Thomas Valerius

J Immunother Cancer· July 2023

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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells.
Marta Lustig, Chilam Chan, J H Marco Jansen, Maria Bräutigam, Max A Kölling, Thomas Valerius

Front Immunol· June 2023

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Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9.
Chilam Chan, Marta Lustig, J H Marco Jansen, Laura Garcia Villagrasa, Leon Raymakers, Thomas Valerius

Cancers (Basel)· June 2023

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Allogeneic hematopoietic cell transplantation for myelodysplastic syndrome unclassifiable - a retrospective study on behalf of the Chronic Malignancies Working Party of the EBMT.
Joanna Drozd-Sokolowska, Luuk Gras, Nienke Zinger, Mohsen Al Zahrani, Jakob Passweg, Thomas Valerius

Bone Marrow Transplant· February 2023

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Correction to: Impact of conditioning regimen intensity on outcomes of second allogeneic hematopoietic cell transplantation for secondary acute myelogenous leukemia.
Arnon Nagler, Christophe Peczynski, Bhagirathbhai Dholaria, Myriam Labopin, Thomas Valerius

Bone Marrow Transplant· December 2022

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Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
Tobias Zeller, Sebastian Lutz, Ira A Münnich, Roland Windisch, Patricia Hilger, Thomas Valerius

Front Immunol· November 2022

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Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab.
Niklas Baumann, Christian Arndt, Judith Petersen, Marta Lustig, Thies Rösner, Thomas Valerius

Front Immunol· September 2022

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Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody.
Carina Lynn Gehlert, Pegah Rahmati, Ammelie Svea Boje, Dorothee Winterberg, Steffen Krohn, Thomas Valerius

Front Immunol· September 2022

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Corrigendum: Targeting myeloid checkpoint molecules in combination with antibody therapy: A novel anti-cancer strategy with IgA antibodies?
Chilam Chan, Marta Lustig, Niklas Baumann, Thomas Valerius, Geert van Tetering

Front Immunol· September 2022

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Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B-cell Precursor Acute Lymphoblastic Leukemia.
Lennart Lenk, Dorothee Winterberg, Fotini Vogiatzi, Anna Laqua, Lea Spory, Thomas Valerius

Hemasphere· August 2022

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