Publications by authors named "Thor Ostenfeld"

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Phase 1, randomized trials of MEDI1341: cerebrospinal fluid free α-synuclein lowered by >50.
Craig Shering, Michael Pomfret, Robert J Kubiak, Isabelle J Pouliquen, Wei Yin, Thor Ostenfeld

Brain Commun· September 2025

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MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.
Christopher Lloyd, Per-Ola Freskgård, Philip Newton, David Lowne, Adrian Nickson, Thor Ostenfeld

Alzheimers Dement· November 2024

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A randomized, placebo-controlled trial of the analgesic efficacy and safety of the p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain from lumbosacral radiculopathy.
Thor Ostenfeld, Alok Krishen, Robert Y Lai, Jonathan Bullman, Joanne Green

Clin J Pain· April 2015

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Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects.
Zahid Ali, Bart Laurijssens, Thor Ostenfeld, Simon McHugh, Anastasia Stylianou

Br J Clin Pharmacol· January 2013

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Human microdose evaluation of the novel EP1 receptor antagonist GSK269984A.
Thor Ostenfeld, Claire Beaumont, Jonathan Bullman, Maria Beaumont, Phillip Jeffrey

Br J Clin Pharmacol· December 2012

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Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.
Praveen Anand, Ravikiran Shenoy, Joanne E Palmer, Amanda J Baines, Robert Y K Lai, Thor Ostenfeld

Eur J Pain· November 2011

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A randomized, controlled study to investigate the analgesic efficacy of single doses of the cannabinoid receptor-2 agonist GW842166, ibuprofen or placebo in patients with acute pain following third molar tooth extraction.
Thor Ostenfeld, Jeffrey Price, Massimo Albanese, Jonathan Bullman, Fiona Guillard

Clin J Pain· October 2011

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Requirement for neurogenesis to proceed through the division of neuronal progenitors following differentiation of epidermal growth factor and fibroblast growth factor-2-responsive human neural stem cells.
Thor Ostenfeld, Clive N Svendsen

Stem Cells· March 2005

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Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons.
Thor Ostenfeld, Yu-Tzu Tai, Peter Martin, Nicole Déglon, Patrick Aebischer

J Neurosci Res· September 2002

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