Publications by authors named "Thorsten Mempel"

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Positioning and reversible suppression of CCR7 dendritic cells in perivascular tumor niches shape cancer immunity.
Beatrice Zitti, Florent Duval, Pratyaksha Wirapati, Mehdi Hicham, Yuxuan Xie, Thorsten R Mempel

Immunity· December 2025

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Intratumoral delivery of 4-1BBL boosts IL-12-triggered anti-glioma immunity.
Taral R Lunavat, Lisa Nieland, Sanne M van de Looij, Alexandra J E M de Reus, Charles P Couturier, Thorsten R Mempel

Mol Ther· November 2025

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Epigenetic therapy sensitizes anti-PD-1 refractory head and neck cancers to immunotherapy rechallenge.
Tingting Qin, Austin K Mattox, Jean S Campbell, Jong Chul Park, Kee-Young Shin, Thorsten R Mempel

J Clin Invest· March 2025

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Chemokines that govern T cell activity in tumors.
Thorsten R Mempel, Mohsen Malehmir

Curr Opin Immunol· February 2025

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Intratumoral gene delivery of 4-1BBL boosts IL-12-triggered anti-glioblastoma immunity.
Taral R Lunavat, Lisa Nieland, Sanne M van de Looij, Alexandra J E M de Reus, Charles P Couturier, Thorsten R Mempel

bioRxiv· February 2025

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The aged tumor microenvironment limits T cell control of cancer.
Alex C Y Chen, Sneha Jaiswal, Daniela Martinez, Cansu Yerinde, Keely Ji, Thorsten R Mempel

Nat Immunol· June 2024

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Interruption of the intratumor CD8 T cell:Treg crosstalk improves the efficacy of PD-1 immunotherapy.
Shannon N Geels, Alexander Moshensky, Rachel S Sousa, Claire Murat, Matias A Bustos, Thorsten R Mempel

Cancer Cell· June 2024

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How chemokines organize the tumour microenvironment.
Thorsten R Mempel, Julia K Lill, Lukas M Altenburger

Nat Rev Cancer· January 2024

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Dendritic cells as shepherds of T cell immunity in cancer.
Mikael J Pittet, Mauro Di Pilato, Christopher Garris, Thorsten R Mempel

Immunity· October 2023

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macrophage polarity identifies a network of cellular programs that control human cancers.
Ruben Bill, Pratyaksha Wirapati, Marius Messemaker, Whijae Roh, Beatrice Zitti, Thorsten R Mempel

Science· August 2023

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Interruption of the Intratumor CD8:Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy.
Shannon N Geels, Alexander Moshensky, Rachel S Sousa, Benjamin L Walker, Rima Singh, Thorsten R Mempel

bioRxiv· May 2023

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Combining precision oncology and immunotherapy by targeting the MALT1 protease.
Thorsten R Mempel, Daniel Krappmann

J Immunother Cancer· October 2022

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CXCL10 chemokine regulates heterogeneity of the CD8 T cell response and viral set point during chronic infection.
Aleksandra J Ozga, Melvyn T Chow, Mateus E Lopes, Rachel L Servis, Mauro Di Pilato, Thorsten R Mempel

Immunity· January 2022

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Behavioural immune landscapes of inflammation.
Georgiana Crainiciuc, Miguel Palomino-Segura, Miguel Molina-Moreno, Jon Sicilia, David G Aragones, Thorsten R Mempel

Nature· January 2022

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T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
Stefanie Lesch, Viktoria Blumenberg, Stefan Stoiber, Adrian Gottschlich, Justyna Ogonek, Thorsten R Mempel

Nat Biomed Eng· November 2021

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Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation.
Max Heckler, Lestat R Ali, Eleanor Clancy-Thompson, Li Qiang, Katherine S Ventre, Thorsten R Mempel

Cancer Discov· October 2021

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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.
Mauro Di Pilato, Raphael Kfuri-Rubens, Jasper N Pruessmann, Aleksandra J Ozga, Marius Messemaker, Thorsten R Mempel

Cell· August 2021

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop.
Francesco Marangoni, Ademi Zhakyp, Michela Corsini, Shannon N Geels, Esteban Carrizosa, Thorsten R Mempel

Cell· July 2021

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Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
Bruno L Cadilha, Mohamed-Reda Benmebarek, Klara Dorman, Arman Oner, Theo Lorenzini, Thorsten R Mempel

Sci Adv· June 2021

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Cancer cells relax and resist cytotoxic attack.
Shariq M Usmani, Thorsten R Mempel

Immunity· May 2021

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Migratory DCs activate TGF-β to precondition naïve CD8 T cells for tissue-resident memory fate.
Vinidhra Mani, Shannon K Bromley, Tarmo Äijö, Rut Mora-Buch, Esteban Carrizosa, Thorsten R Mempel

Science· October 2019

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Targeting the CBM complex causes T cells to prime tumours for immune checkpoint therapy.
Mauro Di Pilato, Edward Y Kim, Bruno L Cadilha, Jasper N Prüßmann, Mazen N Nasrallah, Thorsten R Mempel

Nature· June 2019

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Guidance factors orchestrating regulatory T cell positioning in tissues during development, homeostasis, and response.
Thorsten R Mempel, Francesco Marangoni

Immunol Rev· May 2019

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Atypical complement receptor C5aR2 transports C5a to initiate neutrophil adhesion and inflammation.
Yoshishige Miyabe, Chie Miyabe, Vinidhra Mani, Thorsten R Mempel, Andrew D Luster

Sci Immunol· May 2019

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