Publications by authors named "Thorsten Stiewe"

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Synergistic targeting of cancer cells through simultaneous inhibition of key metabolic enzymes.
Jan Dreute, Julia Stengel, Jonas Becher, David van den Borre, Maximilian Pfisterer, Thorsten Stiewe

Cell Death Differ· December 2025

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p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo.
Oleg Timofeev, Katharina Schlereth, Michael Wanzel, Attila Braun, Bernhard Nieswandt, Thorsten Stiewe

Cell Rep· November 2025

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Hangover regulates gene expression by limiting NSL-mediated H4K16 acetylation.
Jonathan Lenz, Laura Schmelzer, Ignasi Forné, Andrea Nist, Axel Imhof, Thorsten Stiewe

Nucleic Acids Res· November 2025

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Detection of minimal residual disease in circulating cell-free DNA in acute myeloid leukemia.
Charlotte Sommer, Hildegard I D Mack, Madeleine C Killer, Petra Ross, Andrea Nist, Thorsten Stiewe

Sci Rep· September 2025

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Using a novel panel of drug-resistant triple-negative breast cancer cell lines to identify candidate therapeutic targets and biomarkers.
Helen E Grimsley, Magdalena Antczak, Ian G Reddin, Nicole Weiler, Katie-May McLaughlin, Thorsten Stiewe

Cancer Lett· August 2025

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DARPin-induced reactivation of p53 in HPV-positive cells.
Philipp Münick, Alexander Strubel, Dimitrios-Ilias Balourdas, Julianne S Funk, Marco Mernberger, Thorsten Stiewe

Nat Struct Mol Biol· May 2025

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A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages.
Nils Schmerer, Harshavardhan Janga, Michelle Aillaud, Janina Hoffmann, Marina Aznaourova, Thorsten Stiewe

Nat Commun· May 2025

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Basal cell adhesion molecule (BCAM) promotes mesothelial-to-mesenchymal transition and tumor angiogenesis through paracrine signaling.
Suresh Sivakumar, Sonja Lieber, Raimund Dietze, Vanessa M Beutgen, Eileen C Sutor, Thorsten Stiewe

Cell Commun Signal· March 2025

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Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.
Niklas Gremke, Isabelle Besong, Alina Stroh, Luise von Wichert, Marie Witt, Thorsten Stiewe

Signal Transduct Target Ther· March 2025

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Cooperation of a polymerizing SAM domain and an intrinsically disordered region enables full SAMD1 function on chromatin.
Merle Geller, Yinghua Cao, Clara Simon, Bastian Stielow, Jingfei Xu, Thorsten Stiewe

Nucleic Acids Res· March 2025

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TP53: the unluckiest of genes?
Andreas C Joerger, Thorsten Stiewe, Thierry Soussi

Cell Death Differ· February 2025

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Dynamics of molecular heterogeneity in high-risk luminal breast cancer-From intrinsic to adaptive subtyping.
Carsten Denkert, Sivaramakrishna Rachakonda, Thomas Karn, Karsten Weber, Miguel Martin, Thorsten Stiewe

Cancer Cell· February 2025

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Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Julianne S Funk, Maria Klimovich, Daniel Drangenstein, Ole Pielhoop, Pascal Hunold, Thorsten Stiewe

Nat Genet· January 2025

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Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species.
Mohamad K Hammoud, Celina Meena, Raimund Dietze, Nathalie Hoffmann, Witold Szymanski, Thorsten Stiewe

Cell Commun Signal· November 2024

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Molecular adaptation to neoadjuvant immunotherapy in triple-negative breast cancer.
Carsten Denkert, Andreas Schneeweiss, Julia Rey, Thomas Karn, Akira Hattesohl, Thorsten Stiewe

Cell Rep Med· November 2024

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Distinct negative-sense RNA viruses induce a common set of transcripts encoding proteins forming an extensive network.
Nina Hofmann, Marek Bartkuhn, Stephan Becker, Nadine Biedenkopf, Eva Böttcher-Friebertshäuser, Thorsten Stiewe

J Virol· October 2024

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Haptoglobin buffers lipopolysaccharides to delay activation of NFκB.
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel, Bernhard Wilke, Thorsten Stiewe

Front Immunol· October 2024

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DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer.
Anna Brichkina, Miriam Ems, Roman Suezov, Rajeev Singh, Veronika Lutz, Thorsten Stiewe

Gut· September 2024

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Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy.
Stella Logotheti, Athanasia Pavlopoulou, Hamid Khoshfekr Rudsari, Anne-Marie Galow, Yağmur Kafalı, Thorsten Stiewe

Pharmacol Ther· August 2024

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KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma.
Jan Budczies, Eva Romanovsky, Martina Kirchner, Olaf Neumann, Miriam Blasi, Thorsten Stiewe

Br J Cancer· August 2024

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BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells.
Bilal Alashkar Alhamwe, Viviane Ponath, Fahd Alhamdan, Bastian Dörsam, Clara Landwehr, Thorsten Stiewe

Cell Mol Immunol· August 2024

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SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma.
Clara Simon, Inka D Brunke, Bastian Stielow, Ignasi Forné, Anna Mary Steitz, Thorsten Stiewe

PLoS Biol· August 2024

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IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells.
Sabrina Fischer, Lisa Marie Weber, Bastian Stielow, Miriam Frech, Clara Simon, Thorsten Stiewe

Nucleic Acids Res· July 2024

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Transcriptomic response of prostate cancer cells to carbon ion and photon irradiation with focus on androgen receptor and TP53 signaling.
Jörg Hänze, Lilly M Mengen, Marco Mernberger, Dinesh Kumar Tiwari, Thomas Plagge, Thorsten Stiewe

Radiat Oncol· July 2024

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Phosphoproteomics Reveals Selective Regulation of Signaling Pathways by Lysophosphatidic Acid Species in Macrophages.
Raimund Dietze, Witold Szymanski, Kaire Ojasalu, Florian Finkernagel, Andrea Nist, Thorsten Stiewe

Cells· May 2024

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