Publications by authors named "Thuong Trinh-Minh"

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Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation.
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Thuong Trinh-Minh

Arthritis Rheumatol· November 2025

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Avenciguat: a novel soluble guanylate cyclase activator that affects multiple cell types to inhibit IFN-1 signalling and fibrosis.
Julia Kaufman, Gerald Nabozny, Cuong Tran-Manh, Christoph Liebel, Xiang Zhou, Thuong Trinh-Minh

Rheumatology (Oxford)· August 2025

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Antifibrotic effects of specific targeting of the 5-hydroxytryptamine 2B receptor (5-HTR) in murine models and ex vivo models of scleroderma skin.
Thuong Trinh-Minh, Cuong Tran-Manh, Andrea-Hermina Györfi, Nicholas Dickel, Christoph Liebel

Arthritis Rheumatol· August 2025

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Combination therapies of porcupine inhibition with ruxolitinib, ibrutinib, or belumosudil in murine sclerodermatous GVHD.
Xuezhi Hong, Yanhua Xiao, Liyan Xu, Lichong Shen, Ranjana Neelagar, Thuong Trinh-Minh

Blood Adv· March 2025

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Mutual Amplification of GLI2/Hedgehog and Transcription Factor JUN/AP-1 Signaling in Fibroblasts in Systemic Sclerosis: Potential Implications for Combined Therapies.
Christina Bergmann, Sara Chenguiti Fakhouri, Thuong Trinh-Minh, Tim Filla, Aleix Rius Rigau

Arthritis Rheumatol· January 2025

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Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
Caitríona Grönberg, Sara Rattik, Cuong Tran-Manh, Xiang Zhou, Aleix Rius Rigau, Thuong Trinh-Minh

Ann Rheum Dis· August 2024

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Effect of Anti-S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis-Specific Transcriptional Signatures in Human Skin.
Thuong Trinh-Minh, Andrea-Hermina Györfi, Michal Tomcik, Cuong Tran-Manh, Xiang Zhou

Arthritis Rheumatol· May 2024

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S100A4-neutralizing monoclonal antibody 6B12 counteracts the established experimental skin fibrosis induced by bleomycin.
Xiao Švec, Hana Štorkánová, Thuong Trinh-Minh, Manh Cuong Tran, Lenka Štorkánová

Rheumatology (Oxford)· March 2024

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Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis.
Minrui Liang, Nicholas Dickel, Andrea-Hermina Györfi, Bilgesu SafakTümerdem, Yi-Nan Li, Thuong Trinh-Minh

Sci Transl Med· March 2024

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Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis.
Thuong Trinh-Minh, Chih-Wei Chen, Cuong Tran Manh, Yi-Nan Li, Honglin Zhu

J Clin Invest· March 2024

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Amelioration of Fibrotic Remodeling of Human 3-Dimensional Full-Thickness Skin by Transglutamase 2 Inhibition.
Xiang Zhou, Thuong Trinh-Minh, Alexandru-Emil Matei, Andrea-Hermina Györfi, Xuezhi Hong

Arthritis Rheumatol· September 2023

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Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153.
Yi-Nan Li, Chih-Wei Chen, Thuong Trinh-Minh, Honglin Zhu, Alexandru-Emil Matei

Bone Res· July 2022

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Impaired Mitochondrial Transcription Factor A Expression Promotes Mitochondrial Damage to Drive Fibroblast Activation and Fibrosis in Systemic Sclerosis.
Xiang Zhou, Thuong Trinh-Minh, Cuong Tran-Manh, Andreas Gießl, Christina Bergmann

Arthritis Rheumatol· May 2022

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The effect of nintedanib versus mycophenolate mofetil in the Fra2 mouse model of systemic sclerosis-associated interstitial lung disease.
Lutz Wollin, Thuong Trinh-Minh, Yun Zhang, Jörg H W Distler

Clin Exp Rheumatol· August 2021

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X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc).
Christina Bergmann, Ludwig Hallenberger, Sara Chenguiti Fakhouri, Benita Merlevede, Amelie Brandt, Thuong Trinh-Minh

Ann Rheum Dis· August 2021

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Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease.
Yun Zhang, Lichong Shen, Katja Dreißigacker, Honglin Zhu, Thuong Trinh-Minh

Blood· April 2021

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PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis.
Yun Zhang, Lichong Shen, Honglin Zhu, Katja Dreissigacker, Diana Distler, Thuong Trinh-Minh

Ann Rheum Dis· September 2020

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Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis.
Debomita Chakraborty, Honglin Zhu, Astrid Jüngel, Lena Summa, Yi-Nan Li, Thuong Trinh-Minh

Sci Transl Med· September 2020

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Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs.
Alexandru-Emil Matei, Chih-Wei Chen, Lisa Kiesewetter, Andrea-Hermina Györfi, Yi-Nan Li, Thuong Trinh-Minh

Ann Rheum Dis· December 2019

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The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Ariella Zehender, Jingang Huang, Andrea-Hermina Györfi, Alexandru-Emil Matei, Thuong Trinh-Minh

Nat Commun· August 2018

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Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
Chih-Wei Chen, Christian Beyer, Jun Liu, Christiane Maier, Chun Li, Thuong Trinh-Minh

Ann Rheum Dis· April 2017

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