Publications by authors named "Tian-Lu Cheng"

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To generate functional anti-protease-activated receptor-4 (PAR4), a G protein-coupled receptor, antibodies through PAR4-mRNA-LNP immunization.
En-Shuo Liu, Kai-Wen Ho, Chin-Chung Wu, Hsiao-Li Fan, Ting-Yu Wang, Bo-Cheng Huang, Tian-Lu Cheng

NPJ Vaccines· November 2025

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Spatial-hindrance-based pro-Adalimumab prevents anti-idiotypic antibody interference in pharmacokinetic and therapeutic efficacy.
Bo-Cheng Huang, Yu-Tung Chen, Yun-Chi Lu, Kai-Wen Ho, Shih-Ting Hong, Tian-Lu Cheng

Bioeng Transl Med· September 2025

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Development of a tumor-region-selective activation monoclonal antibody targeting the 4-1BB receptor for enhanced therapeutic efficacy and safety.
Tzu-Yi Liao, Yen-Ling Liu, Chiao-Yun Chen, Bing-Tsung Wu, En-Shuo Liu, Bo-Cheng Huang, Yi-An Cheng, Tian-Lu Cheng

Int J Biol Macromol· May 2025

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Protease-activated anti-Lewis Y antibody enhances selectivity and safety of glycan-targeting cancer therapy.
Wen-Han Lee, Ying-Rou Shen, Bo-Cheng Huang, Kai-Wen Ho, Ching-Kuei Chen, Yi-An Cheng, Tian-Lu Cheng

Int J Biol Macromol· May 2025

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Targeted internalization and activation of glycosidic switch liposomes by a biological macromolecule mPEG×EphA2 increases therapeutic efficacy against lung cancer.
Kai-Wen Ho, Yen-Ling Liu, Bo-Cheng Huang, Shih-Ting Hong, Shih-Hung Yang, Tian-Lu Cheng

Int J Biol Macromol· April 2025

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pH-Responsive Polyethylene Glycol Engagers for Enhanced Brain Delivery of PEGylated Nanomedicine to Treat Glioblastoma.
Jun-Lun Meng, Zi-Xuan Dong, Yan-Ru Chen, Meng-Hsuan Lin, Yu-Ching Liu, Tian-Lu Cheng, Yen-Cheng Lin, Yu-Cheng Su

ACS Nano· January 2025

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Impact of Pre-existing Anti-polyethylene Glycol Antibodies on the Pharmacokinetics and Efficacy of a COVID-19 mRNA Vaccine (Comirnaty) In Vivo.
Yen-Ling Liu, Tzu-Yi Liao, Kai-Wen Ho, En-Shuo Liu, Bo-Cheng Huang, Tian-Lu Cheng

Biomater Res· December 2024

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Corrigendum to "Selective activation of IFNγ-ipilimumab enhances the therapeutic effect and safety of ipilimumab" [Int. J. Biol. Macromol. 265(Pt 2) (Apr 2024) 130945].
Yi-Jung Huang, Kai-Wen Ho, Tian-Lu Cheng, Yen-Tseng Wang, Shi-Wei Chao, Bo-Cheng Huang

Int J Biol Macromol· November 2024

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Strategies for Non-Covalent Attachment of Antibodies to PEGylated Nanoparticles for Targeted Drug Delivery.
Kai-Wen Ho, Yen-Ling Liu, Tzu-Yi Liao, En-Shuo Liu, Tian-Lu Cheng

Int J Nanomedicine· October 2024

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Integrating molecular dynamics simulation with small- and wide-angle X-ray scattering to unravel the flexibility, antigen-blocking, and protease-restoring functions in a hindrance-based pro-antibody.
Jun Min Liao, Shih-Ting Hong, Yeng-Tseng Wang, Yi-An Cheng, Kai-Wen Ho, Tian-Lu Cheng

Protein Sci· September 2024

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Corrigendum to "Selective activation of IFNγ-ipilimumab enhances the therapeutic effect and safety of ipilimumab" [Int. J. Biol. Macromol. 265(Pt 2) (Apr 2024) 130945].
Yi-Jung Huang, Kai-Wen Ho, Tian-Lu Cheng, Yen-Tseng Wang, Shi-Wei Chao, Bo-Cheng Huang

Int J Biol Macromol· September 2024

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MicroRNA-195-5p Inhibits Intracerebral Hemorrhage-Induced Inflammatory Response and Neuron Cell Apoptosis.
Yi-Cheng Tsai, Chih-Hui Chang, Yoon Bin Chong, Chieh-Hsin Wu, Hung-Pei Tsai, Tian-Lu Cheng

Int J Mol Sci· September 2024

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Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies.
Bing-Mae Chen, Even Chen, Yi-Chen Lin, Trieu Thi My Tran, Keren Turjeman, Tian-Lu Cheng

ACS Nano· August 2024

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MicroRNA-195-5p Attenuates Intracerebral-Hemorrhage-Induced Brain Damage by Inhibiting MMP-9/MMP-2 Expression.
Yi-Cheng Tsai, Chih-Hui Chang, Yoon Bin Chong, Chieh-Hsin Wu, Hung-Pei Tsai, Tian-Lu Cheng

Biomedicines· June 2024

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Selective activation of IFNγ-ipilimumab enhances the therapeutic effect and safety of ipilimumab.
Yi-Jung Huang, Kai-Wen Ho, Tian-Lu Cheng, Yen-Tseng Wang, Shi-Wei Chao, Bo-Cheng Huang

Int J Biol Macromol· April 2024

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Exploring the therapeutic potential of DV-B-120 as an inhibitor of dengue virus infection.
Yi-Jung Huang, Tian-Lu Cheng, Yen-Tseng Wang, Chien-Shu Chen, Yu-Ling Leu, Cheng-Han Ho

J Virol· April 2024

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A Low-Cost, Sensitive Reporter System Using Membrane-Tethered Horseradish Peroxidase for Efficient Gene Expression Analysis.
Mu-Shen Chang, Chia-Yi Lee, En-Shuo Liu, Hsuan Chao, Hsin-Yu Wu, Yu-Cheng Su, Tian-Lu Cheng, Cheng-Wei Lin

Anal Chem· September 2023

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Development of NS2B-NS3 protease inhibitor that impairs Zika virus replication.
Wen-Wei Lin, Yi-Jung Huang, Yen-Tseng Wang, Yun-Syuan Lin, Nonsikelelo Mazibuko, Tian-Lu Cheng

Virus Res· May 2023

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A non-genetic engineering platform for rapidly generating and expanding cancer-specific armed T cells.
Yi-Jou Chen, Michael Chen, Tian-Lu Cheng, Yi-Shan Tsai, Chang-Hung Wang, Jing-Jy Cheng

J Biomed Sci· May 2023

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XPF-ERCC1 Blocker Improves the Therapeutic Efficacy of 5-FU- and Oxaliplatin-Based Chemoradiotherapy in Colorectal Cancer.
Ming-Yii Huang, Yi-Jung Huang, Tian-Lu Cheng, Wun-Ya Jhang, Chien-Chih Ke

Cells· May 2023

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A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis.
Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou, Yu-Ching Hsieh, Bo-Cheng Huang, Yu-Cheng Su, Tian-Lu Cheng

Inflamm Regen· February 2023

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Fumarate hydratase inhibits non-small cell lung cancer metastasis via inactivation of AMPK and upregulation of DAB2.
Anupama Vadhan, Yi-Fang Yang, Yun-Ming Wang, Pang-Yu Chen, Shey-Cherng Tzou, Kuang-Hung Cheng, Tian-Lu Cheng

Oncol Lett· January 2023

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Engineering a High-Affinity Anti-Methoxy Poly(ethylene glycol) (mPEG) Antibody for Sensitive Immunosensing of mPEGylated Therapeutics and mPEG Molecules.
Chiao-Yu Hsiao, Jun-Lun Meng, Jung-Zhe Hong, Xuan-Huong Ly, Meng-Hsuan Lin, Tian-Lu Cheng, Yu-Cheng Su

Bioconjug Chem· November 2022

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Micro-PET imaging of hepatitis C virus NS3/4A protease activity using a protease-activatable retention probe.
Chih-Hung Chuang, Tian-Lu Cheng, Wei-Chun Chen, Yi-Jung Huang, Hsin-Ell Wang

Front Microbiol· November 2022

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CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2.
Anupama Vadhan, Ming-Feng Hou, Priya Vijayaraghavan, Yi-Chia Wu, Stephen Chu-Sung Hu, Tian-Lu Cheng

Biomedicines· October 2022

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