Publications by authors named "Tian-le Xu"

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Segregated supramammillary-dentate gyrus circuits modulate cognitive and affective function in healthy and Alzheimer's disease model mice.
Yan-Jia Luo, Longfei Li, Ze-Ka Chen, Ping Dong, Ling Xie, Xiao-Hong Xu, Nan-Jie Xu, Tian Xue, Tian-Le Xu

Neuron· December 2025

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Lcn2 from neutrophil extracellular traps induces astrogliosis and post-stroke emotional disorders.
Yuan Liu, Wei Lin, Zhongfei Bai, Yuting Ge, Yuanjie Xiao, Tian-Le Xu

Neuron· December 2025

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Nonionotropic action of an acid-sensing ion channel inhibits leukemogenesis in the acidic bone marrow niche.
Hao Gu, Lietao Weng, Chiqi Chen, Xiaoxin Hao, Rongkun Tao, Tian-Le Xu

J Clin Invest· December 2025

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Transcriptomics and Proteomics Identify Serotonin Transporter as a Promising Therapeutic Target for Essential Tremor.
Lingbing Wang, Zhuofan Zhou, Suzhen Lin, Yanjing Li, Shaoyi Zhang, Tian-Le Xu

Mol Cell Proteomics· November 2025

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Dysfunction of the paraventricular thalamus-prelimbic cortex circuit underlies maternal separation-induced deficits in contagious pain.
Zichen Zhang, Yu Gong, Xin-Yu Su, Yujiao Deng, Rui Du, Tian-Le Xu

Sci Adv· October 2025

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A noncanonical parasubthalamic nucleus-to-extended amygdala circuit converts chronic social stress into anxiety.
Na Liu, Jun Wang, Huan Wang, Bin Gao, Zheng Lin, Tian-Le Xu, Han Xu

J Clin Invest· August 2025

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Upregulation of Acid-Sensing Ion Channel 1a in the Anterior Cingulate Cortex by TNF-α/NF-κB Pathway Contributes to Diabetes-Related Pain.
Ai-Jun Jiang, Hong-Rui Wei, Sijia Chu, Mengyuan Wang, Jinling Yan, Tian-Le Xu

Diabetes· June 2025

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PIEZO1 mediates mechanical reprogramming of neutrophils for proangiogenic specialization in the lung.
Jin Wang, Wenying Zhao, Wenjuan Bai, Dong Dong, Hui Wang, Tian-le Xu

J Clin Invest· June 2025

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Stimulation of an entorhinal-hippocampal extinction circuit facilitates fear extinction in a post-traumatic stress disorder model.
Ze-Jie Lin, Xue Gu, Wan-Kun Gong, Mo Wang, Yan-Jiao Wu, Tian-Le Xu

J Clin Invest· September 2024

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Amygdala neuronal dyshomeostasis via 5-HT receptors mediates mood and cognitive defects in Alzheimer's disease.
Xin-Rong Wu, Xiao-Na Zhu, Yuan-Bo Pan, Xue Gu, Xian-Dong Liu, Tian-Le Xu, Nan-Jie Xu

Aging Cell· August 2024

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A thalamic nucleus reuniens-lateral septum-lateral hypothalamus circuit for comorbid anxiety-like behaviors in chronic itch.
Su-Shan Guo, Yu Gong, Ting-Ting Zhang, Xin-Yu Su, Yan-Jiao Wu, Xuan Zhao, Tian-Le Xu

Sci Adv· August 2024

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Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury.
Ke Lai, Iva Pritišanac, Zhen-Qi Liu, Han-Wei Liu, Li-Na Gong, Tian-Le Xu

Nature· July 2024

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An ultra-short-acting benzodiazepine in thalamic nucleus reuniens undermines fear extinction via intermediation of hippocamposeptal circuits.
Hoiyin Cheung, Tong-Zhou Yu, Xin Yi, Yan-Jiao Wu, Qi Wang, Xue Gu, Miao Xu, Tian-Le Xu

Commun Biol· June 2024

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Sensory ASIC3 channel exacerbates psoriatic inflammation via a neurogenic pathway in female mice.
Chen Huang, Pei-Yi Sun, Yiming Jiang, Yuandong Liu, Zhichao Liu, Tian-Le Xu

Nat Commun· June 2024

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The basal forebrain to lateral habenula circuitry mediates social behavioral maladaptation.
Jun Wang, Qian Yang, Xue Liu, Jie Li, Ya-Lan Wen, Tian-Le Xu, Han Xu

Nat Commun· May 2024

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Developmental Patterns and Gender Differences of Vocal Production in Marmoset Monkeys.
Ruixin An, Chaocheng Lu, Chen Wang, Liangtang Chang, Junfeng Huang, Tian-Le Xu

Neurosci Bull· January 2024

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Genetically Encoded Photocatalysis Enables Spatially Restricted Optochemical Modulation of Neurons in Live Mice.
Kaixing Zeng, Zhi-Han Jiao, Qin Jiang, Ru He, Yixin Zhang, Tian-Le Xu

ACS Cent Sci· January 2024

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Representation and control of pain and itch by distinct prefrontal neural ensembles.
Qian Pan, Su-Shan Guo, Ming Chen, Xin-Yu Su, Zi-Long Gao, Tian-Le Xu

Neuron· August 2023

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Lidocaine alleviates inflammation and pruritus in atopic dermatitis by blocking different population of sensory neurons.
Pei-Yi Sun, Hua-Guo Li, Qian-Yue Xu, Zhen Zhang, Jia-Wen Chen, Tian-Le Xu

Br J Pharmacol· May 2023

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An Anterior Cingulate Cortex-to-Midbrain Projection Controls Chronic Itch in Mice.
Ting-Ting Zhang, Su-Shan Guo, Hui-Ying Wang, Qi Jing, Xin Yi, Tian-Le Xu, Xuan Zhao

Neurosci Bull· May 2023

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Synaptic scaling of corticostriatal circuits underlies hyperactivity in GABA Transporter-1 deficient mice.
Yan-Jiao Wu, Xin Yi, Xue Gu, Qi Wang, Qin Jiang, Tian-Le Xu

iScience· April 2023

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EphB2-dependent prefrontal cortex activation promotes long-range social approach and partner responsiveness.
Li-Na He, Si Chen, Qi Yang, Zheng Wu, Zheng-Kai Lao, Xiao-Hong Xu, Tian-Le Xu, Nan-Jie Xu

Proc Natl Acad Sci U S A· February 2023

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Dynamic tripartite construct of interregional engram circuits underlies forgetting of extinction memory.
Xue Gu, Yan-Jiao Wu, Zichen Zhang, Jia-Jie Zhu, Xin-Rong Wu, Miao Xu, Nan-Jie Xu, Tian-Le Xu

Mol Psychiatry· October 2022

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Excitatory SST neurons in the medial paralemniscal nucleus control repetitive self-grooming and encode reward.
Jingjing Sun, Yuan Yuan, Xiaohua Wu, Anqi Liu, Jingjie Wang, Tian-Le Xu

Neuron· October 2022

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Insular cortical circuits as an executive gateway to decipher threat or extinction memory via distinct subcortical pathways.
Qi Wang, Jia-Jie Zhu, Lizhao Wang, Yan-Peng Kan, Yan-Mei Liu, Xue Gu, Nan-Jie Xu, Tian-Le Xu

Nat Commun· September 2022

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