Publications by authors named "Tiffany Todd"

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Endolysosomal dysfunction impairs proteostasis and induces neurodegeneration .
Wei Shao, Ellen A Albagli, Karen Jansen-West, Lillian M Daughrity, Jimei Tong, Tiffany W Todd

iScience· October 2025

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Cryo-EM structures of pathogenic fibrils and their impact on neurodegenerative disease research.
Tiffany W Todd, Naeyma N Islam, Casey N Cook, Thomas R Caulfield, Leonard Petrucelli

Neuron· July 2024

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Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43.
Paula Castellanos Otero, Tiffany W Todd, Wei Shao, Caroline J Jones, Kexin Huang

PLoS One· April 2024

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TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia.
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd

Sci Transl Med· January 2024

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The endolysosomal pathway and ALS/FTD.
Tiffany W Todd, Wei Shao, Yong-Jie Zhang, Leonard Petrucelli

Trends Neurosci· December 2023

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TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains.
Virginia Estades Ayuso, Sarah Pickles, Tiffany Todd, Mei Yue, Karen Jansen-West

Mol Neurodegener· August 2023

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Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration.
Wei Shao, Tiffany W Todd, Yanwei Wu, Caroline Y Jones, Jimei Tong

Science· October 2022

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Amyotrophic lateral sclerosis - insight into susceptibility.
Tiffany W Todd, Leonard Petrucelli

Nat Rev Neurol· April 2022

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Modelling amyotrophic lateral sclerosis in rodents.
Tiffany W Todd, Leonard Petrucelli

Nat Rev Neurosci· April 2022

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Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model.
Karen Jansen-West, Tiffany W Todd, Lillian M Daughrity, Mei Yue, Jimei Tong

Front Cell Dev Biol· March 2022

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HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS.
Giulia Del Rosso, Yari Carlomagno, Tiffany W Todd, Caroline Y Jones, Mercedes Prudencio

Front Cell Dev Biol· January 2022

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Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD.
Yanwei Wu, Wei Shao, Tiffany W Todd, Jimei Tong, Mei Yue

Cell Rep· August 2021

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Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
Zachary T McEachin, Tania F Gendron, Nisha Raj, María García-Murias, Anwesha Banerjee, Tiffany W Todd

Neuron· July 2020

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Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo.
Tiffany W Todd, Zachary T McEachin, Jeannie Chew, Alexander R Burch, Karen Jansen-West

Cell Rep· May 2020

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Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.
Tiffany W Todd, Leonard Petrucelli

J Neurochem· August 2016

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Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy.
Tiffany W Todd, Hiroshi Kokubu, Helen C Miranda, Constanza J Cortes, Albert R La Spada

Elife· August 2015

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Aggregation formation in the polyglutamine diseases: protection at a cost?
Tiffany W Todd, Janghoo Lim

Mol Cells· September 2013

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Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1.
Hyoungseok Ju, Hiroshi Kokubu, Tiffany W Todd, Juliette J Kahle, Soeun Kim

J Neurosci· May 2013

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