Publications by authors named "Tim Avis"

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The Novel DNA Binding Mechanism of Ridinilazole, a Precision Antibiotic.
Clive S Mason, Tim Avis, Chenlin Hu, Nabeetha Nagalingam, Manikhandan Mudaliar

Antimicrob Agents Chemother· May 2023

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Targeted microbiome-sparing antibiotics.
Tim Avis, Francis X Wilson, Nawaz Khan, Clive S Mason, David J Powell

Drug Discov Today· September 2021

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High-density transposon libraries utilising outward-oriented promoters identify mechanisms of action and resistance to antimicrobials.
Chris Coward, Gopujara Dharmalingham, Omar Abdulle, Tim Avis, Stephan Beisken

FEMS Microbiol Lett· December 2020

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Patterns of somatic mutation in human cancer genomes.
Christopher Greenman, Philip Stephens, Raffaella Smith, Gillian L Dalgliesh, Christopher Hunter, Tim Avis

Nature· March 2007

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Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor.
Patrick S Tarpey, F Lucy Raymond, Sarah O'Meara, Sarah Edkins, Jon Teague, Tim Avis

Am J Hum Genet· February 2007

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Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.
Patrick S Tarpey, Claire Stevens, Jon Teague, Sarah Edkins, Sarah O'Meara, Tim Avis

Am J Hum Genet· December 2006

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
Ogechi N Ikediobi, Helen Davies, Graham Bignell, Sarah Edkins, Claire Stevens, Tim Avis

Mol Cancer Ther· November 2006

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A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
Chris Hunter, Raffaella Smith, Daniel P Cahill, Philip Stephens, Claire Stevens, Tim Avis

Cancer Res· April 2006

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Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
Graham Bignell, Raffaella Smith, Chris Hunter, Philip Stephens, Helen Davies, Tim Avis

Genes Chromosomes Cancer· January 2006

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Somatic mutations of the protein kinase gene family in human lung cancer.
Helen Davies, Chris Hunter, Raffaella Smith, Philip Stephens, Chris Greenman, Tim Avis

Cancer Res· September 2005

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A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.
Philip Stephens, Sarah Edkins, Helen Davies, Chris Greenman, Charles Cox, Tim Avis

Nat Genet· June 2005

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