Publications by authors named "Tim Beissert"

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Long-lasting mRNA-encoded interleukin-2 restores CD8 T cell neoantigen immunity in MHC class I-deficient cancers.
Jan D Beck, Mustafa Diken, Martin Suchan, Michael Streuber, Elif Diken

Cancer Cell· August 2024

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-amplifying RNA expressing functional miRNA mediates target gene suppression and simultaneous transgene expression.
Ayşegül Yıldız, Aida Hasani, Tina Hempel, Nina Köhl, Aline Beicht, Tim Beissert

Mol Ther Nucleic Acids· June 2024

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Long-lasting mRNA-encoded interleukin-2 restores CD8 T cell neoantigen immunity in MHC class I-deficient cancers.
Jan D Beck, Mustafa Diken, Martin Suchan, Michael Streuber, Elif Diken

Cancer Cell· April 2024

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Trans-Amplifying RNA: A Journey from Alphavirus Research to Future Vaccines.
Ayşegül Yıldız, Cristian Răileanu, Tim Beissert

Viruses· March 2024

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A trans-amplifying RNA simplified to essential elements is highly replicative and robustly immunogenic in mice.
Mario Perkovic, Stefanie Gawletta, Tina Hempel, Silke Brill, Evelin Nett, Tim Beissert

Mol Ther· January 2024

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A trans-amplifying RNA simplified to essential elements is highly replicative and robustly immunogenic in mice.
Mario Perkovic, Stefanie Gawletta, Tina Hempel, Silke Brill, Evelin Nett, Tim Beissert

Mol Ther· July 2023

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A trans-amplifying RNA simplified to essential elements is highly replicative and robustly immunogenic in mice.
Mario Perkovic, Stefanie Gawletta, Tina Hempel, Silke Brill, Evelin Nett, Tim Beissert

Mol Ther· June 2023

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A Bivalent Trans-Amplifying RNA Vaccine Candidate Induces Potent Chikungunya and Ross River Virus Specific Immune Responses.
Christin Schmidt, Florian D Hastert, Julia Gerbeth, Tim Beissert, Ugur Sahin

Vaccines (Basel)· August 2022

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A taRNA vaccine candidate induces a specific immune response that protects mice against Chikungunya virus infections.
Christin Schmidt, Erik Haefner, Julia Gerbeth, Tim Beissert, Ugur Sahin

Mol Ther Nucleic Acids· June 2022

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PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation.
Diana Barea Roldán, Matthias Grimmler, Christoph Hartmann, Stefanie Hubich-Rau, Tim Beißert

Oncotarget· May 2020

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A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective Immunity.
Tim Beissert, Mario Perkovic, Annette Vogel, Stephanie Erbar, Kerstin C Walzer

Mol Ther· January 2020

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Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3' UTRs Identified by Cellular Library Screening.
Alexandra G Orlandini von Niessen, Marco A Poleganov, Corina Rechner, Arianne Plaschke, Lena M Kranz, Tim Beissert

Mol Ther· April 2019

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Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice.
Sebastian Rosigkeit, Martin Meng, Christian Grunwitz, Patricia Gomes, Andreas Kreft, Tim Beissert

Mol Pharm· September 2018

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Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses.
Annette B Vogel, Laura Lambert, Ekaterina Kinnear, David Busse, Stephanie Erbar, Tim Beissert

Mol Ther· February 2018

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Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion Proteins.
Tim Beissert, Lars Koste, Mario Perkovic, Kerstin C Walzer, Stephanie Erbar

Hum Gene Ther· December 2017

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Antigen-specific oncolytic MV-based tumor vaccines through presentation of selected tumor-associated antigens on infected cells or virus-like particles.
Stefan Hutzler, Stephanie Erbar, Robert A Jabulowsky, Jan R H Hanauer, Jürgen H Schnotz, Tim Beissert

Sci Rep· December 2017

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A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform.
Anna H Malczyk, Alexandra Kupke, Steffen Prüfer, Vivian A Scheuplein, Stefan Hutzler, Tim Beissert

J Virol· November 2015

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Efficient Reprogramming of Human Fibroblasts and Blood-Derived Endothelial Progenitor Cells Using Nonmodified RNA for Reprogramming and Immune Evasion.
Marco Alexander Poleganov, Sarah Eminli, Tim Beissert, Stephanie Herz, Jung-Il Moon

Hum Gene Ther· November 2015

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Targeting of the N-terminal coiled coil oligomerization interface by a helix-2 peptide inhibits unmutated and imatinib-resistant BCR/ABL.
Tim Beissert, Alena Hundertmark, Velina Kaburova, Lorena Travaglini, Afsar A Mian

Int J Cancer· June 2008

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Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells.
Xiaomin Zheng, Anita Seshire, Brigitte Rüster, Gesine Bug, Tim Beissert

Haematologica· March 2007

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BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.
Xiaomin Zheng, Saskia Güller, Tim Beissert, Elena Puccetti, Martin Ruthardt

BMC Cancer· November 2006

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The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.
Elena Puccetti, Xiaomin Zheng, Daria Brambilla, Anita Seshire, Tim Beissert

Cancer Res· July 2005

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Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.
Gesine Bug, Hilal Gül, Kerstin Schwarz, Heike Pfeifer, Manuela Kampfmann, Tim Beissert

Cancer Res· April 2005

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Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.
Xiaomin Zheng, Tim Beissert, Natasa Kukoc-Zivojnov, Elena Puccetti, Joachim Altschmied

Blood· May 2004

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Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis.
Elena Puccetti, Tim Beissert, Saskia Güller, Jun E Li, Dieter Hoelzer

Oncogene· October 2003

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