Publications by authors named "Tim Brend"

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Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol.
Mark A Hull, Pei Loo Ow, Sharon Ruddock, Tim Brend, Alexandra F Smith

BMJ Open· November 2023

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Correction: Brüning-Richardson et al. GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models. 2021, , 5939.
Anke Brüning-Richardson, Gary C Shaw, Daniel Tams, Tim Brend, Hitesh Sanganee

Cancers (Basel)· August 2022

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HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme.
Einthavy Arunachalam, William Rogers, Guy R Simpson, Carla Möller-Levet, Gemma Bolton, Tim Brend

BMC Cancer· April 2022

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GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models.
Anke Brüning-Richardson, Gary C Shaw, Daniel Tams, Tim Brend, Hitesh Sanganee

Cancers (Basel)· November 2021

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EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.
Nina Struve, Zev A Binder, Lucy F Stead, Tim Brend, Stephen J Bagley

Oncogene· April 2020

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Cancer cell killing by target antigen engagement with engineered complementary intracellular antibody single domains fused to pro-caspase3.
Jennifer S Chambers, Tim Brend, Terence H Rabbitts

Sci Rep· June 2019

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shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.
Harry R Haynes, Helen L Scott, Clare L Killick-Cole, Gary Shaw, Tim Brend

J Pathol· April 2019

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Drug-Repositioning Screens Identify Triamterene as a Selective Drug for the Treatment of DNA Mismatch Repair Deficient Cells.
Delphine Guillotin, Philip Austin, Rumena Begum, Marta O Freitas, Ashirwad Merve, Tim Brend

Clin Cancer Res· June 2017

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RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells.
Harry O King, Tim Brend, Helen L Payne, Alexander Wright, Thomas A Ward

Stem Cell Reports· January 2017

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Sequential gene targeting to make chimeric tumor models with de novo chromosomal abnormalities.
Jennifer S Chambers, Tomoyuki Tanaka, Tim Brend, Hanif Ali, Nicola J Geisler

Cancer Res· March 2014

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The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub.
Anna Trofka, Jamie Schwendinger-Schreck, Tim Brend, William Pontius, Thierry Emonet

Development· March 2012

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Expression of the oscillating gene her1 is directly regulated by Hairy/Enhancer of Split, T-box, and Suppressor of Hairless proteins in the zebrafish segmentation clock.
Tim Brend, Scott A Holley

Dev Dyn· November 2009

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Balancing segmentation and laterality during vertebrate development.
Tim Brend, Scott A Holley

Semin Cell Dev Biol· June 2009

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Zebrafish whole mount high-resolution double fluorescent in situ hybridization.
Tim Brend, Scott A Holley

J Vis Exp· March 2009

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Multiple levels of transcriptional and post-transcriptional regulation are required to define the domain of Hoxb4 expression.
Tim Brend, Jonathan Gilthorpe, Dennis Summerbell, Peter W J Rigby

Development· June 2003

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Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY.
Jonathan Gilthorpe, Marie Vandromme, Tim Brend, Alejandro Gutman, Dennis Summerbell

Development· August 2002

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