Publications by authors named "Tim Bugni"

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Utilizing the HiBiT System to Identify CARM1 Degraders for Targeted Cancer Therapy.
Megan Bacabac, Mingshan Hu, Fabao Liu, Eui-Jun Kim, Tanja Grkovic, Tim S Bugni

J Med Chem· December 2025

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Actinomycetoquinones A-E, Anthraquinone-γ-Pyrones Discovered from Marine-Derived sp. Bacterium.
Fan Zhang, Christopher D Roberts, Tae Hyun Lee, Doug R Braun, Zachary D Bennett, Tim S Bugni

J Nat Prod· October 2025

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Discovery and Biosynthetic Interrogation of a Cobalt-Containing Terpene-Polyketide-Nonribosomal Peptide Tribrid with Anticoronavirus Activity.
Dan Xue, Qihao Wu, Lukuan Hou, Conor Pulliam, Mingming Xu, Tim S Bugni

J Am Chem Soc· October 2025

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IDBac: an open-access web platform and compendium for the identification of bacteria by MALDI-TOF mass spectrometry.
Nyssa K Krull, Michael Strobel, Julia Saulog, Liana Zaroubi, Bruno S Paulo, Tim S Bugni

bioRxiv· October 2025

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Cytochrome P450 Mediated Cyclohexane Ring Formation in Forazoline Biosynthesis.
Xinru Chen, Yujie Zhang, Shiqi Li, Weiting Liao, Weixin Tao, Tim S Bugni

Angew Chem Int Ed Engl· July 2025

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Evidence for Divergence of the Genus '' Within the Bacterial Family .
Hailee I Porter, Imraan Alas, Nyssa K Krull, Doug R Braun, Scott R Rajski, Tim S Bugni

Microorganisms· July 2025

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Discovery of New Everninomicin Analogs from a Marine-Derived sp. by Metabolomics and Genomics Approaches.
Tae Hyun Lee, Nathan J Brittin, Imraan Alas, Christopher D Roberts, Shaurya Chanana, Tim S Bugni

Mar Drugs· July 2025

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Detection of N-labeled metabolites in microbial extracts using AI-designed broadband pulses for H, N heteronuclear NMR spectroscopy.
Manu V S, Marco Tonelli, Bailey Bell, Alok K Sharma, Tim S Bugni

Analyst· April 2025

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Machine Learning-Based Bioactivity Classification of Natural Products Using LC-MS/MS Metabolomics.
Nathaniel J Brittin, Josephine M Anderson, Doug R Braun, Scott R Rajski, Cameron R Currie, Tim S Bugni

J Nat Prod· February 2025

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Ion Mobility-Coupled Mass Spectrometry for Metallophore Detection.
Bailey A Bell, Josephine M Anderson, Scott R Rajski, Tim S Bugni

J Nat Prod· February 2025

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Isolation, Structure Elucidation and Biological Evaluation of Lomaiviticins F-H, Dimeric Benzofluorene Glycosides from Marine-Derived sp. Bacterium.
Fan Zhang, Wenhui Wang, Doug R Braun, Gene E Ananiev, Weiting Liao, Tim S Bugni

Mar Drugs· February 2025

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Discovery of a Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads.
Dan Xue, Mingming Xu, Michael D Madden, Xiaoying Lian, Ethan A Older, Tim S Bugni

J Am Chem Soc· January 2025

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Directed Evolution of an Adenylation Domain Alters Substrate Specificity and Generates a New Catechol Siderophore in .
Erin Conley, Caryn S Wadler, Bailey A Bell, Ivy Lucier, Caroline Haynie, Tim S Bugni

Biochemistry· December 2024

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Dereplication of Natural Product Antifungals via Liquid Chromatography-Tandem Mass Spectrometry and Chemical Genomics.
Nathaniel J Brittin, David J Aceti, Doug R Braun, Josephine M Anderson, Spencer S Ericksen, Tim S Bugni

Molecules· December 2024

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Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads.
Dan Xue, Mingming Xu, Michael D Madden, Xiaoying Lian, Ethan A Older, Tim S Bugni

bioRxiv· November 2024

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biosynthetic gene cluster diversity highlights the need for broad-spectrum investigations.
Imraan Alas, Doug R Braun, Spencer S Ericksen, Rauf Salamzade, Lindsay Kalan, Tim S Bugni

Microb Genom· January 2024

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Rapid Unambiguous Structure Elucidation of Streptnatamide A, a New Cyclic Peptide Isolated from A Marine-derived Streptomyces sp.
Jia-Xuan Yan, Qihao Wu, Mitasree Maity, Doug R Braun, Imraan Alas, Tim S Bugni

Chemistry· October 2023

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Metabolomics and Genomics Enable the Discovery of a New Class of Nonribosomal Peptidic Metallophores from a Marine .
Qihao Wu, Bailey A Bell, Jia-Xuan Yan, Marc G Chevrette, Nathan J Brittin, Tim S Bugni

J Am Chem Soc· January 2023

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Genomic diversification of the specialized parasite of the fungus-growing ant symbiosis.
Kirsten Gotting, Daniel S May, Jeffrey Sosa-Calvo, Lily Khadempour, Charlotte B Francoeur, Tim S Bugni

Proc Natl Acad Sci U S A· December 2022

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A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation.
Mustafa Özçam, Jee-Hwan Oh, Restituto Tocmo, Deepa Acharya, Shenwei Zhang, Tim S Bugni

Cell Host Microbe· June 2022

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Genome Mining and Metabolomics Unveil Pseudonochelin: A Siderophore Containing 5-Aminosalicylate from a Marine-Derived sp. Bacterium.
Fan Zhang, René F Ramos Alvarenga, Kurt Throckmorton, Shaurya Chanana, Doug R Braun, Tim S Bugni

Org Lett· June 2022

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Bacillimidazoles A-F, Imidazolium-Containing Compounds Isolated from a Marine .
Jia-Xuan Yan, Qihao Wu, Eric J N Helfrich, Marc G Chevrette, Doug R Braun, Tim S Bugni

Mar Drugs· January 2022

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High Throughput Small Molecule Screen for Reactivation of in Fragile X Syndrome Human Neural Cells.
Jack F V Hunt, Meng Li, Ryan Risgaard, Gene E Ananiev, Scott Wildman, Tim S Bugni

Cells· December 2021

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Phenyl-Lactic Acid Is an Active Ingredient in Bactericidal Supernatants of Lactobacillus crispatus.
Omar Abdul-Rahim, Qihao Wu, Travis K Price, Giuseppe Pistone, Katherine Diebel, Tim S Bugni

J Bacteriol· September 2021

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Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel.
Christina M Scribano, Jun Wan, Karla Esbona, John B Tucker, Amber Lasek, Tim S Bugni

Sci Transl Med· September 2021

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