Publications by authors named "Tim D Fryer"

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Azathioprine for the treatment of early Parkinson's disease (AZA-PD): a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial.
Julia C Greenland, Kerry Dresser, Emma Cutting, Rachel Donegan, Simon Bond, Tim D Fryer

Lancet Neurol· January 2026

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Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.
Hannah de Bruin, Colin Groot, Henryk Barthel, Gérard N Bischof, Ganna Blazhenets, Tim D Fryer

Brain· November 2025

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Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease.
Marta Camacho, Julia C Greenland, Alexander R D Peattie, Lennart R B Spindler, Jonathan Holbrook, Tim D Fryer

Mov Disord· November 2025

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Comparing and combining TSPO-PET tracers in tauopathies.
Harry Crook, Nicolai Franzmeier, Nesrine Rahmouni, Johannes S Gnörich, Tim D Fryer

Eur J Nucl Med Mol Imaging· October 2025

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Peripheral-central immune crosstalk in Parkinson's disease and its association with clinical severity.
Julia C Greenland, Jonathan Holbrook, Lakmini Kahanawita, Marta Camacho, Tim D Fryer

Brain Behav Immun· August 2025

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Post-mortem validation of in vivo TSPO PET as a microglial biomarker.
Sasvi S Wijesinghe, James B Rowe, Hannah D Mason, Kieren S J Allinson, Reuben Thomas, Tim D Fryer

Brain· June 2025

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Blood inflammation relates to neuroinflammation and survival in frontotemporal lobar degeneration.
Maura Malpetti, Peter Swann, Kamen A Tsvetanov, Leonidas Chouliaras, Alexandra Strauss, Tim D Fryer

Brain· February 2025

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Extra-axial inflammatory signal and its relationship to peripheral and central immunity in depression.
Brandi Eiff, Edward T Bullmore, Menna R Clatworthy, Tim D Fryer, Carmine M Pariante

Brain· February 2025

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Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.
Anna McKeever, Peter Swann, Maura Malpetti, Paul C Donaghy, Alan Thomas, Tim D Fryer

Alzheimers Dement· February 2025

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Outcomes and Mechanisms Associated With Selective Thalamic Neuronal Loss in Chronic Traumatic Brain Injury.
Rebecca E Woodrow, Julia Grossac, Young T Hong, Stefan Winzeck, Thomas Geeraerts, Tim D Fryer

JAMA Netw Open· August 2024

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Are central and systemic inflammation associated with fatigue in cerebral small vessel disease?
Amy A Jolly, Robin B Brown, Daniel J Tozer, Young T Hong, Tim D Fryer

Int J Stroke· July 2024

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Differential Synaptic Loss in β-Amyloid Positive Versus β-Amyloid Negative Corticobasal Syndrome.
Negin Holland, George Savulich, P Simon Jones, David J Whiteside, Duncan Street, Tim D Fryer

Mov Disord· July 2024

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MINocyclinE to Reduce inflammation and blood-brain barrier leakage in small Vessel diseAse (MINERVA): A phase II, randomized, double-blind, placebo-controlled experimental medicine trial.
Robin B Brown, Daniel J Tozer, Laurence Loubière, Eric L Harshfield, Young T Hong, Tim D Fryer

Alzheimers Dement· June 2024

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Neuroinflammation is linked to dementia risk in Parkinson's disease.
Antonina Kouli, Lennart R B Spindler, Tim D Fryer, Young T Hong, Maura Malpetti

Brain· March 2024

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Synaptic density affects clinical severity via network dysfunction in syndromes associated with frontotemporal lobar degeneration.
David J Whiteside, Negin Holland, Kamen A Tsvetanov, Elijah Mak, Maura Malpetti, Tim D Fryer

Nat Commun· December 2023

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PET/MRI of hypoxia and vascular function in ER-positive breast cancer: correlations with immunohistochemistry.
Julia C Carmona-Bozo, Roido Manavaki, Jodi L Miller, Cara Brodie, Corradina Caracò, Tim D Fryer

Eur Radiol· September 2023

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Microglial activation in the frontal cortex predicts cognitive decline in frontotemporal dementia.
Maura Malpetti, Thomas E Cope, Duncan Street, P Simon Jones, Frank H Hezemans, Tim D Fryer

Brain· August 2023

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Longitudinal Synaptic Loss in Primary Tauopathies: An In Vivo [ C]UCB-J Positron Emission Tomography Study.
Negin Holland, P Simon Jones, George Savulich, Michelle Naessens, Maura Malpetti, Tim D Fryer

Mov Disord· July 2023

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Do Regions of Increased Inflammation Progress to New White Matter Hyperintensities?: A Longitudinal Positron Emission Tomography-Magnetic Resonance Imaging Study.
Daniel J Tozer, Robin B Brown, Jessica Walsh, Young T Hong, Guy B Williams, Tim D Fryer

Stroke· February 2023

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Synaptic Loss in Frontotemporal Dementia Revealed by [ C]UCB-J Positron Emission Tomography.
Maura Malpetti, P Simon Jones, Thomas E Cope, Negin Holland, Michelle Naessens, Tim D Fryer

Ann Neurol· January 2023

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Novel Approach for Assessing Postinfarct Myocardial Injury and Inflammation Using Hybrid Somatostatin Receptor Positron Emission Tomography/Magnetic Resonance Imaging.
Andrej Ćorović, Deepa Gopalan, Christopher Wall, Marta Peverelli, Stephen P Hoole, Tim D Fryer

Circ Cardiovasc Imaging· January 2023

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Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis.
Andrej Ćorović, Christopher Wall, Meritxell Nus, Deepa Gopalan, Yuan Huang, Tim D Fryer

J Am Coll Cardiol· January 2023

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Amyloid- β and tau deposition influences cognitive and functional decline in Down syndrome.
Monika Grigorova, Elijah Mak, Stephanie S G Brown, Jessica Beresford-Webb, Young T Hong, Tim D Fryer

Neurobiol Aging· November 2022

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MINocyclinE to Reduce inflammation and blood brain barrier leakage in small Vessel diseAse (MINERVA) trial study protocol.
Robin B Brown, Daniel J Tozer, Laurence Loubière, Young T Hong, Tim D Fryer

Eur Stroke J· September 2022

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