Publications by authors named "Tim Dierckx"

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Multi-cohort cross-omics analysis reveals disease mechanisms and therapeutic targets in HTLV-1-associated myelopathy, a neglected retroviral neuroinflammatory disorder.
Johan Van Weyenbergh, Tatiane Assone, Isaac Racine, Soraya Menezes, Fernanda Gonçalves, Tim Dierckx

Res Sq· April 2025

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Phylogenetic Analysis of Hepatitis C Virus Infections in a Large Belgian Cohort Using Next-Generation Sequencing of Full-Length Genomes.
Kasper T Christensen, Florian Pierard, David Bonsall, Rory Bowden, Eleanor Barnes, Tim Dierckx

Viruses· December 2023

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Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation.
Tatiane Assone, Soraya Maria Menezes, Fernanda de Toledo Gonçalves, Victor Angelo Folgosi, Gabriela da Silva Prates, Tim Dierckx

J Neuroinflammation· December 2022

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Full-genome next-generation sequencing of hepatitis C virus to assess the accuracy of genotyping by the commercial assay LiPA and the prevalence of resistance-associated substitutions in a Belgian cohort.
Kasper T Christensen, Florian Pierard, Kurt Beuselinck, David Bonsall, Rory Bowden, Tim Dierckx

J Clin Virol· October 2022

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Urinary Peptides as Potential Non-Invasive Biomarkers for Lupus Nephritis: Results of the Peptidu-LUP Study.
Maxence Tailliar, Joost P Schanstra, Tim Dierckx, Benjamin Breuil, Guillaume Hanouna

J Clin Med· April 2021

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XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis.
Eline Boons, Tatiane C Nogueira, Tim Dierckx, Soraya Maria Menezes, Maarten Jacquemyn

Blood Cancer J· February 2021

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enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9.
Jasper Edgar Neggers, Maarten Jacquemyn, Tim Dierckx, Benjamin Peter Kleinstiver, Hendrik Jan Thibaut

Mol Ther· January 2021

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Serum GlycA Level is Elevated in Active Systemic Lupus Erythematosus and Correlates to Disease Activity and Lupus Nephritis Severity.
Tim Dierckx, Laurent Chiche, Laurent Daniel, Bernard Lauwerys, Johan Van Weyenbergh

J Clin Med· March 2020

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An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans.
Murilo Delgobo, Daniel Agb Mendes, Edgar Kozlova, Edroaldo Lummertz Rocha, Gabriela F Rodrigues-Luiz, Tim Dierckx

Elife· October 2019

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Decreased RORC expression and downstream signaling in HTLV-1-associated adult T-cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for immunotherapy?
Kritika Subramanian, Tim Dierckx, Ricardo Khouri, Soraya Maria Menezes, Huseini Kagdi

Int J Cancer· April 2019

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GlycA, a Nuclear Magnetic Resonance Spectroscopy Measure for Protein Glycosylation, is a Viable Biomarker for Disease Activity in IBD.
Tim Dierckx, Bram Verstockt, Séverine Vermeire, Johan van Weyenbergh

J Crohns Colitis· March 2019

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Immune Signatures and Microbial Load at the Nasopharyngeal Interface in Children With Acute Respiratory Infection.
Kiyoshi F Fukutani, Cristiana M Nascimento-Carvalho, Maiara L Bouzas, Juliana R Oliveira, Aldina Barral, Tim Dierckx

Front Microbiol· November 2018

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Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC.
Nádia Conceição-Neto, Ward Deboutte, Tim Dierckx, Kathleen Machiels, Jun Wang

Gut· August 2018

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Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the and IFN-β Response in HTLV-1-Associated Neuroinflammation.
Fabio E Leal, Soraya Maria Menezes, Emanuela A S Costa, Phillip M Brailey, Lucio Gama, Tim Dierckx

Front Microbiol· May 2018

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ISG15-Induced IL-10 Is a Novel Anti-Inflammatory Myeloid Axis Disrupted during Active Tuberculosis.
Paula Fernandes Dos Santos, Johan Van Weyenbergh, Murilo Delgobo, Daniel de Oliveira Patricio, Brian J Ferguson, Tim Dierckx

J Immunol· February 2018

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Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes.
Jasper Edgar Neggers, Bert Kwanten, Tim Dierckx, Hiroki Noguchi, Arnout Voet

Nat Commun· February 2018

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A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients.
Ricardo Khouri, Gilvanéia Silva-Santos, Tim Dierckx, Soraya Maria Menezes, Daniele Decanine

Oncoimmunology· February 2018

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Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis.
Áislan de Carvalho Vivarini, Teresa Cristina Calegari-Silva, Alessandra Mattos Saliba, Viviane Sampaio Boaventura, Jaqueline França-Costa, Tim Dierckx

Front Immunol· September 2017

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A Fas Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation.
Soraya Maria Menezes, Fabio E Leal, Tim Dierckx, Ricardo Khouri, Daniele Decanine

Front Immunol· February 2017

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Inflammatory Gene Expression Profile and Defective Interferon-γ and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients.
Karen Put, Jessica Vandenhaute, Anneleen Avau, Annemarie van Nieuwenhuijze, Ellen Brisse, Tim Dierckx

Arthritis Rheumatol· January 2017

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Detection of Natural Resistance-Associated Substitutions by Ion Semiconductor Technology in HCV1b Positive, Direct-Acting Antiviral Agents-Naïve Patients.
Nadia Marascio, Grazia Pavia, Alessio Strazzulla, Tim Dierckx, Lize Cuypers

Int J Mol Sci· August 2016

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Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection.
Kiyoshi F Fukutani, Cristiana M Nascimento-Carvalho, Winke Van der Gucht, Elke Wollants, Ricardo Khouri, Tim Dierckx

J Clin Virol· August 2015

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