Publications by authors named "Tim Frenzel"

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The impact of a noise reduction bundle on ICU staff: A stepped-wedge cluster randomized clinical trial.
Jeanette Vreman, Cris Lanting, Tim Frenzel, Johannes G van der Hoeven, Joris Lemson

Intensive Crit Care Nurs· December 2025

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Population pharmacokinetics and optimized dosing of cefuroxime in critically ill patients.
Jaap W A Mouton, Julian D Machiels, Arthur M A Pistorius, Rob Ter Heine, Tim Frenzel

Br J Clin Pharmacol· September 2025

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Effects of angiotensin 2 infusion on the RAAS and alternative RAAS pathway.
Chema Strik-Lips, Dirk van Lier, Antonius Eduard van Herwaarden, Tim Frenzel, Peter Pickkers

Crit Care· August 2025

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Hemodynamic effects of adjunct arginine vasopressin to norepinephrine in septic shock: insights from a prospective multicenter registry study.
Max Melchers, Vivienne de Smet, Chrissie Rooijakkers, Jonathan Huising, Wander Vermeulen, Tim Frenzel

Ann Intensive Care· April 2025

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Long-term mortality of Dutch COVID-19 patients admitted to the intensive care medicine: a retrospective analysis from a national quality registry.
Safira A Wortel, Ferishta Bakhshi-Raiez, Ameen Abu-Hanna, Dave A Dongelmans, Nicolette F de Keizer, Tim Frenzel

Crit Care Sci· January 2025

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Reduction of sound levels in the intermediate care unit; a quasi-experimental time-series design study.
Vreman Jeanette, Lanting Cris, Frenzel Tim, van der Hoeven Johannes G, Lemson Joris

Intensive Crit Care Nurs· December 2024

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Open Versus Closed Suctioning in Invasively Ventilated Critically Ill Patients for Sustainability of ICU Care: A Life-Cycle Assessment Comparison.
Willemke Stilma, Andrea Esmeijer, Frederique Paulus, Tim Frenzel, Hugo Touw

Respir Care· January 2024

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Optimizing an existing prediction model for quality of life one-year post-intensive care unit: An exploratory analysis.
Manon de Jonge, Nina Wubben, Christiaan R van Kaam, Tim Frenzel, Cornelia W E Hoedemaekers

Acta Anaesthesiol Scand· November 2022

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INCIDENCE, RISK FACTORS, AND OUTCOME OF SUSPECTED CENTRAL VENOUS CATHETER-RELATED INFECTIONS IN CRITICALLY ILL COVID-19 PATIENTS: A MULTICENTER RETROSPECTIVE COHORT STUDY.
Jasper M Smit, Lotte Exterkate, Arne J van Tienhoven, Mark E Haaksma, Micah L A Heldeweg, Tim Frenzel

Shock· November 2022

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Assess and validate predictive performance of models for in-hospital mortality in COVID-19 patients: A retrospective cohort study in the Netherlands comparing the value of registry data with high-granular electronic health records.
Iacopo Vagliano, Martijn C Schut, Ameen Abu-Hanna, Dave A Dongelmans, Dylan W de Lange, Tim Frenzel

Int J Med Inform· November 2022

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Predicting responders to prone positioning in mechanically ventilated patients with COVID-19 using machine learning.
Tariq A Dam, Luca F Roggeveen, Fuda van Diggelen, Lucas M Fleuren, Ameet R Jagesar, Tim Frenzel

Ann Intensive Care· October 2022

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Correction to: An Integral Pharmacokinetic Analysis of Piperacillin and Tazobactam in Plasma and Urine in Critically Ill Patients.
Eveline Wallenburg, Rob Ter Heine, Jeroen A Schouten, Jelmer Raaijmakers, Jaap Ten Oever, Tim Frenzel

Clin Pharmacokinet· September 2022

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Effects of dalteparin on anti-Xa activities cannot be predicted in critically ill COVID-19 patients.
Charlotte D C C van der Heijden, Rob Ter Heine, Emma J Kooistra, Roger J Brüggemann, Jesper W J Walburgh Schmidt, Tim Frenzel

Br J Clin Pharmacol· June 2022

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An Integral Pharmacokinetic Analysis of Piperacillin and Tazobactam in Plasma and Urine in Critically Ill Patients.
Eveline Wallenburg, Rob Ter Heine, Jeroen A Schouten, Jelmer Raaijmakers, Jaap Ten Oever, Tim Frenzel

Clin Pharmacokinet· June 2022

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Using long-term predicted Quality of Life in ICU clinical practice to prepare patients for life post-ICU: A feasibility study.
Nina Wubben, Marieke Zegers, Laurens L A Bisschops, Tim Frenzel, Johannes G van der Hoeven

J Crit Care· April 2022

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Rapid Evaluation of Coronavirus Illness Severity (RECOILS) in intensive care: Development and validation of a prognostic tool for in-hospital mortality.
Drago Plečko, Nicolas Bennett, Johan Mårtensson, Tariq A Dam, Robert Entjes, Tim Frenzel

Acta Anaesthesiol Scand· January 2022

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Predictors for extubation failure in COVID-19 patients using a machine learning approach.
Lucas M Fleuren, Tariq A Dam, Michele Tonutti, Daan P de Bruin, Robbert C A Lalisang, Tim Frenzel

Crit Care· December 2021

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High unbound flucloxacillin fraction in critically ill patients.
Eveline Wallenburg, Rob Ter Heine, Dylan W de Lange, Henk van Leeuwen, Jeroen A Schouten, Tim Frenzel

J Antimicrob Chemother· November 2021

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Development of a practically usable prediction model for quality of life of ICU survivors: A sub-analysis of the MONITOR-IC prospective cohort study.
Nina Wubben, Mark van den Boogaard, Jordache Ramjith, Laurens L A Bisschops, Tim Frenzel

J Crit Care· October 2021

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Some Patients Are More Equal Than Others: Variation in Ventilator Settings for Coronavirus Disease 2019 Acute Respiratory Distress Syndrome.
Tariq A Dam, Harm-Jan de Grooth, Thomas Klausch, Lucas M Fleuren, Daan P de Bruin, Tim Frenzel

Crit Care Explor· October 2021

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Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients.
Emma J Kooistra, Miranda van Berkel, Noortje F van Kempen, Celine R M van Latum, Niklas Bruse, Tim Frenzel

Crit Care· August 2021

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The Dutch Data Warehouse, a multicenter and full-admission electronic health records database for critically ill COVID-19 patients.
Lucas M Fleuren, Tariq A Dam, Michele Tonutti, Daan P de Bruin, Robbert C A Lalisang, Tim Frenzel

Crit Care· August 2021

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Risk factors for adverse outcomes during mechanical ventilation of 1152 COVID-19 patients: a multicenter machine learning study with highly granular data from the Dutch Data Warehouse.
Lucas M Fleuren, Michele Tonutti, Daan P de Bruin, Robbert C A Lalisang, Tariq A Dam, Tim Frenzel

Intensive Care Med Exp· June 2021

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Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19.
Nico A F Janssen, Inge Grondman, Aline H de Nooijer, Collins K Boahen, Valerie A C M Koeken, Tim Frenzel

J Infect Dis· April 2021

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Breath-synchronized electrical stimulation of the expiratory muscles in mechanically ventilated patients: a randomized controlled feasibility study and pooled analysis.
Annemijn H Jonkman, Tim Frenzel, Euan J McCaughey, Angus J McLachlan, Claire L Boswell-Ruys

Crit Care· October 2020

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