Publications by authors named "Tim Koopmans"

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Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation.
Tim Koopmans, Eva van Rooij

Nat Rev Cardiol· November 2025

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Maintaining the LYVE1 line through macrophage and lymphatic interplay in the regenerating neonatal heart.
Tim Koopmans, Eva van Rooij

Nat Cardiovasc Res· October 2025

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Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition.
Louk T Timmer, Elvira den Hertog, Danielle Versteeg, Harm Post, Job A J Verdonschot, Tim Koopmans

Cardiovasc Res· May 2025

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ATF3's shielding hand to counter ischemia-reperfusion injury in cardiac macrophages.
Tim Koopmans, Alejandro Cardona-Monzonís, Eva van Rooij

Nat Cardiovasc Res· January 2024

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Spatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse () ear.
Henriëtte van Beijnum, Tim Koopmans, Antonio Tomasso, Vanessa Disela, Severin Te Lindert

Genome Res· August 2023

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Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration.
Phong D Nguyen, Iris Gooijers, Giulia Campostrini, Arie O Verkerk, Hessel Honkoop, Tim Koopmans

Science· May 2023

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An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ().
Antonio Tomasso, Tim Koopmans, Philip Lijnzaad, Kerstin Bartscherer, Ashley W Seifert

Sci Adv· April 2023

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A dualistic approach to heart repair through FGF10.
Tim Koopmans, Eva van Rooij

Cardiovasc Res· September 2022

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Neutrophils direct preexisting matrix to initiate repair in damaged tissues.
Adrian Fischer, Juliane Wannemacher, Simon Christ, Tim Koopmans, Safwen Kadri

Nat Immunol· April 2022

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Ischemic tolerance and cardiac repair in the spiny mouse (Acomys).
Tim Koopmans, Henriette van Beijnum, Elke F Roovers, Antonio Tomasso, Divyanshu Malhotra

NPJ Regen Med· November 2021

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Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces.
Adrian Fischer, Tim Koopmans, Pushkar Ramesh, Simon Christ, Maximilian Strunz

Nat Commun· June 2020

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Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation.
Tim Koopmans, Laura Hesse, Martijn C Nawijn, Kuldeep Kumawat, Mark H Menzen

Sci Rep· April 2020

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Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers.
Jonathan M Tsai, Rahul Sinha, Jun Seita, Nathaniel Fernhoff, Simon Christ, Tim Koopmans

Sci Transl Med· November 2018

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Mesothelial to mesenchyme transition as a major developmental and pathological player in trunk organs and their cavities.
Tim Koopmans, Yuval Rinkevich

Commun Biol· October 2018

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Revisiting asthma therapeutics: focus on WNT signal transduction.
Tim Koopmans, Reinoud Gosens

Drug Discov Today· January 2018

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β-Catenin Directs Nuclear Factor-κB p65 Output CREB-Binding Protein/p300 in Human Airway Smooth Muscle.
Tim Koopmans, Roos Eilers, Mark Menzen, Andrew Halayko, Reinoud Gosens

Front Immunol· September 2017

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Selective targeting of CREB-binding protein/β-catenin inhibits growth of and extracellular matrix remodelling by airway smooth muscle.
Tim Koopmans, Stijn Crutzen, Mark H Menzen, Andrew J Halayko, Tillie-Louise Hackett

Br J Pharmacol· December 2016

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Cooperative signaling by TGF-β1 and WNT-11 drives sm-α-actin expression in smooth muscle via Rho kinase-actin-MRTF-A signaling.
Kuldeep Kumawat, Tim Koopmans, Mark H Menzen, Alita Prins, Marieke Smit

Am J Physiol Lung Cell Mol Physiol· September 2016

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Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction.
Tim Koopmans, Kuldeep Kumawat, Andrew J Halayko, Reinoud Gosens

Sci Rep· July 2016

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β-catenin as a regulator and therapeutic target for asthmatic airway remodeling.
Kuldeep Kumawat, Tim Koopmans, Reinoud Gosens

Expert Opin Ther Targets· September 2014

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