Publications by authors named "Tim Lock"

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The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?
Stacey J Sukoff Rizzo, Sarah K Leonard, Adam Gilbert, Paul Dollings, Deborah L Smith, Tim Lock

J Pharmacol Exp Ther· July 2011

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Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).
Chiara Ghiron, Simon N Haydar, Suzan Aschmies, Hendrick Bothmann, Cristiana Castaldo, Tim Lock

J Med Chem· June 2010

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Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide).
John Dunlop, Tim Lock, Brian Jow, Fabrizio Sitzia, Steven Grauer

J Pharmacol Exp Ther· March 2009

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Pharmacological comparison of muscarinic ligands: historical versus more recent muscarinic M1-preferring receptor agonists.
Julia N Heinrich, John A Butera, Tikva Carrick, Angela Kramer, Dianne Kowal, Tim Lock

Eur J Pharmacol· March 2009

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In vitro screening strategies for nicotinic receptor ligands.
John Dunlop, Renza Roncarati, Brian Jow, Hendrick Bothmann, Tim Lock

Biochem Pharmacol· October 2007

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