Publications by authors named "Tim Mandelkow"

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High-level STING expression in tumour and inflammatory cells is linked to microsatellite instability and favourable tumour parameters in a cohort of over 1,900 colorectal cancer patients.
Elena Bady, Julia Ebner, Tim Mandelkow, Zhihao Huang, Michael Neipp

Pathology· December 2025

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Prevalence, Immune Checkpoint Expression, and Spatial Interplay of Immune Cells Are Linked to Favorable Tumor Phenotype in 4915 Human Carcinomas.
Zhihao Huang, Tim Mandelkow, Jonas B Raedler, Elena Bady, Jan H Müller

Lab Invest· December 2025

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A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.
Zhihao Huang, Tim Mandelkow, Nicolaus F Debatin, Magalie C J Lurati, Julia Ebner

J Pathol· June 2025

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Prognostic Impact and Spatial Interplay of Immune Cells in Urothelial Cancer.
Nicolaus F Debatin, Elena Bady, Tim Mandelkow, Zhihao Huang, Magalie C J Lurati

Eur Urol· July 2024

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Loss of TROP2 and epithelial cell adhesion molecule expression is linked to grade progression in pTa but unrelated to disease outcome in pT2-4 urothelial bladder carcinomas.
Jan H Müller, Henning Plage, Sefer Elezkurtaj, Tim Mandelkow, Zhihao Huang

Front Oncol· January 2024

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Automated Prognosis Marker Assessment in Breast Cancers Using BLEACH&STAIN Multiplexed Immunohistochemistry.
Tim Mandelkow, Elena Bady, Magalie C J Lurati, Jonas B Raedler, Jan H Müller

Biomedicines· November 2023

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BLEACH&STAIN 15-marker Multiplexed Imaging in 3,098 Human Carcinomas Reveals Six Major PD-L1-driven Immune Phenotypes with Distinct Spatial Orchestration.
Elena Bady, Katharina Möller, Tim Mandelkow, Jonas B Raedler, Cheng Yang

Mol Cancer Res· June 2023

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Automated Ki-67 labeling index assessment in prostate cancer using artificial intelligence and multiplex fluorescence immunohistochemistry.
Niclas C Blessin, Cheng Yang, Tim Mandelkow, Jonas B Raedler, Wenchao Li

J Pathol· May 2023

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Nonredundant Upregulation of CD112R (PVRIG) and PD-1 on Cytotoxic T Lymphocytes Located in T Cell Nests of Colorectal Cancer.
Cheng Yang, Tim Mandelkow, Elena Bady, Jonas B Raedler, Ronald Simon

Mod Pathol· April 2023

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PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples.
Katharina Möller, Madeleine Knöll, Elena Bady, Max Jonathan Schmerder, Sebastian Dwertmann Rico, Tim Mandelkow

Cancer Biomark· February 2023

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Correction to: MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes.
Christoph Fraune, Eike Burandt, Ronald Simon, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Tim Mandelkow

Ann Surg Oncol· September 2022

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T-Cell Density at the Invasive Margin and Immune Phenotypes Predict Outcome in Vulvar Squamous Cell Cancer.
Eike Burandt, Niclas C Blessin, Ann-Christin Rolschewski, Florian Lutz, Tim Mandelkow

Cancers (Basel)· August 2022

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Semi-automated validation and quantification of CTLA-4 in 90 different tumor entities using multiple antibodies and artificial intelligence.
David Dum, Tjark L C Henke, Tim Mandelkow, Cheng Yang, Elena Bady

Lab Invest· June 2022

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Prognostic role of proliferating CD8 cytotoxic Tcells in human cancers.
Niclas C Blessin, Wenchao Li, Tim Mandelkow, Hannah L Jansen, Cheng Yang

Cell Oncol (Dordr)· August 2021

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Prevalence of proliferating CD8 cells in normal lymphatic tissues, inflammation and cancer.
Niclas C Blessin, Raed Abu-Hashem, Tim Mandelkow, Wenchao Li, Ronald Simon

Aging (Albany NY)· June 2021

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High level of EZH2 expression is linked to high density of CD8-positive T-lymphocytes and an aggressive phenotype in renal cell carcinoma.
Till Eichenauer, Luca Simmendinger, Christoph Fraune, Tim Mandelkow, Niclas C Blessin

World J Urol· February 2021

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MMR Deficiency is Homogeneous in Pancreatic Carcinoma and Associated with High Density of Cd8-Positive Lymphocytes.
Christoph Fraune, Eike Burandt, Ronald Simon, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Tim Mandelkow

Ann Surg Oncol· October 2020

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Prevalence of CD8 cytotoxic lymphocytes in human neoplasms.
Niclas C Blessin, Patrick Spriestersbach, Wenchao Li, Tim Mandelkow, David Dum

Cell Oncol (Dordr)· June 2020

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High RSF1 protein expression is an independent prognostic feature in prostate cancer.
Doris Höflmayer, Moslim Hamuda, Cornelia Schroeder, Claudia Hube-Magg, Ronald Simon, Tim Mandelkow

Acta Oncol· March 2020

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Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients.
Franziska Büscheck, Mariam Sulimankhil, Nathaniel Melling, Doris Höflmayer, Claudia Hube-Magg, Tim Mandelkow

Cancer Med· February 2020

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Immune Exclusion Is Frequent in Small-Cell Carcinoma of the Bladder.
Tim Mandelkow, Niclas C Blessin, Eva Lueerss, Laura Pott, Ronald Simon

Dis Markers· December 2019

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Upregulation of SPDEF is associated with poor prognosis in prostate cancer.
Jan Meiners, Katharina Schulz, Katharina Möller, Doris Höflmayer, Christoph Burdelski, Tim Mandelkow

Oncol Lett· November 2019

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Expression of the immune checkpoint receptor TIGIT in seminoma.
Andrea Hinsch, Niclas C Blessin, Ronald Simon, Martina Kluth, Kristine Fischer, Tim Mandelkow

Oncol Lett· August 2019

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Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer.
Niclas C Blessin, Ronald Simon, Martina Kluth, Kristine Fischer, Claudia Hube-Magg, Tim Mandelkow

Dis Markers· May 2019

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Expression of the immune checkpoint receptor TIGIT in Hodgkin's lymphoma.
Wenchao Li, Niclas C Blessin, Ronald Simon, Martina Kluth, Kristine Fischer, Tim Mandelkow

BMC Cancer· December 2018

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