Publications by authors named "Tim Tippin"

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Assessing Cytochrome P450 Drug Interaction Risk for Dordaviprone Using Physiologically Based Pharmacokinetic Modeling.
Swati Jaiswal, Nikunjkumar K Patel, Hannah M Jones, Savannah McFeely, Shamia L Faison, Tim Tippin

CPT Pharmacometrics Syst Pharmacol· October 2025

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A phase 1, randomized, crossover trial to assess the effect of itraconazole on the pharmacokinetics of dordaviprone in healthy adults.
Shamia L Faison, Joelle Batonga, Thangam Arumugham, Angela Bartkus, Marion E Morrison, Tim Tippin

Br J Clin Pharmacol· September 2025

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Effect of Severe Renal Impairment on Dordaviprone (ONC201) Pharmacokinetics.
Shamia L Faison, Joelle Batonga, Thangam Arumugham, Angela Bartkus, Marion E Morrison, Tim Tippin

Drugs R D· September 2025

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A Phase 1 Study to Evaluate the Absorption, Metabolism, and Disposition of Dordaviprone in Healthy Adult Participants.
Yohannes Teffera, Tim Tippin, Angela Bartkus, Francine A de Castro, Shamia L Faison

Clin Pharmacol Drug Dev· July 2025

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A Phase 1 Randomized Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Escalating Oral Doses of Dordaviprone and the Effects of Food on the Bioavailability of Dordaviprone in Healthy Adult Subjects.
Shamia L Faison, Joelle Batonga, Thangam Arumugham, Angela Bartkus, Marion Morrison, Tim Tippin

Clin Pharmacol Drug Dev· May 2025

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Relative Bioavailability of Dordaviprone (ONC201) is Not Affected by Co-Administration of the Proton-Pump Inhibitor Rabeprazole.
Shamia L Faison, Joelle Batonga, Thangam Arumugham, Angela Bartkus, Marion Morrison, Tim Tippin

J Clin Pharmacol· April 2025

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Peripheral blood mononuclear cells isolation from mouse and rabbit blood to quantify active nucleotide and define brincidofovir dose for smallpox.
Robert Hart, Shane Karnik, Kathy Van Sickle, Mark Mullin, Odin Naderer, Tim Tippin

Bioanalysis· November 2024

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Utility of Cytochrome P450 4F2 Genotyping to Assess Drug Interaction Risk for Brincidovovir, a Cytochrome P450 4F2 Substrate.
Tim Tippin, Shamia Faison, Virna Schuck, John Dunn, Odin Naderer

Clin Pharmacol Drug Dev· March 2024

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Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001.
Kris Paolino, Jane Sande, Evelio Perez, Brett Loechelt, Barbara Jantausch, Tim Tippin

J Clin Virol· February 2011

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Development of CMX001 for the Treatment of Poxvirus Infections.
Randall Lanier, Lawrence Trost, Tim Tippin, Bernhard Lampert, Alice Robertson

Viruses· December 2010

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Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.
Jon L Collins, Adam M Fivush, Michael A Watson, Cristin M Galardi, Michael C Lewis, Tim K Tippin

J Med Chem· May 2002

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
Sean B Joseph, Elaine McKilligin, Liming Pei, Michael A Watson, Alan R Collins, Tim K Tippin

Proc Natl Acad Sci U S A· May 2002

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