Publications by authors named "Tim Yu"

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Individualized therapy development for rare diseases: individualized at every step of the way.
Marlen C Lauffer, Tim Yu, Annemieke Aarstma-Rus

Ther Adv Rare Dis· October 2025

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The Rare Therapies Launchpad: a pilot program for individualized medicines in the UK.
Daniel J O'Connor, Parker Moss, Matthew Wood, Martin Murphy, Michael Parker, Tim Yu

Nat Med· May 2025

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The state-of-the-art of N-of-1 therapies and the IRDiRC N-of-1 development roadmap.
Anneliene H Jonker, Elena-Alexandra Tataru, Holm Graessner, David Dimmock, Adam Jaffe, Tim Yu

Nat Rev Drug Discov· January 2025

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The Use of Steroids to Treat Hypercalcemia Due to Granulomatous Disease From Disseminated Coccidioidomycosis.
Tim Yu, Stephen Bruce, Diep Nguyen, Anika Patel, Mark MacElwee

Cureus· July 2024

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Oligonucleotides and  = 1 Therapeutics: From the Patient Perspective to Chemistry, Manufacturing, and Control.
Tim Yu, Daniel O'Reilly

Nucleic Acid Ther· April 2022

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A Unique Mouse Model of Early Life Exercise Enables Hippocampal Memory and Synaptic Plasticity.
Autumn S Ivy, Tim Yu, Enikö Kramár, Sonia Parievsky, Fred Sohn

Sci Rep· June 2020

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A curated gene list for reporting results of newborn genomic sequencing.
Ozge Ceyhan-Birsoy, Kalotina Machini, Matthew S Lebo, Tim W Yu, Pankaj B Agrawal

Genet Med· July 2017

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Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures.
Xiaochang Zhang, Jiqiang Ling, Giulia Barcia, Lili Jing, Jiang Wu, Tim W Yu

Am J Hum Genet· April 2014

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Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice.
Eun-Gyoung Hong, Brian W Kim, Dae Young Jung, Jong Hun Kim, Tim Yu

Endocrinology· October 2013

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Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome.
M Chiara Manzini, Dimira E Tambunan, R Sean Hill, Tim W Yu, Thomas M Maynard

Am J Hum Genet· September 2012

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Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.
Eun-Gyoung Hong, Hwi Jin Ko, You-Ree Cho, Hyo-Jeong Kim, Zhexi Ma, Tim Y Yu

Diabetes· November 2009

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The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation.
Toshiya Atsumi, You-Ree Cho, Lin Leng, Courtney McDonald, Tim Yu

J Immunol· October 2007

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