Publications by authors named "Tim-Philipp Simon"

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Persistent low serum zinc is associated with recurrent sepsis in critically ill patients - A pilot study.
Janine Hoeger, Tim-Philipp Simon, Thorben Beeker, Gernot Marx, Hajo Haase, Tobias Schuerholz

September 2017

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Efficacy and Safety of a Balanced Gelatine Solution for Fluid Resuscitation in Sepsis: A Prospective, Randomised, Controlled, Double-Blind Trial-GENIUS Trial.
Gernot Marx, Jan Benes, Ricard Ferrer, Dietmar Fries, Johannes Ehler, Tim-Philipp Simon

J Clin Med· July 2025

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Implementation and One-Year Evaluation of Proenkephalin A in Critical Care.
Lukas Martin, Caren Martin, Arne Peine, Matthias Imöhl, Alexander Kersten, Tim-Philipp Simon

Int J Mol Sci· March 2025

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Ribonuclease inhibitor 1 emerges as a potential biomarker and modulates inflammation and iron homeostasis in sepsis.
Carolina Neu, Christian Beckers, Nadine Frank, Katharina Thomas, Matthias Bartneck, Tim-Philipp Simon

Sci Rep· June 2024

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Diaphragm ultrasound in patients with prolonged weaning from mechanical ventilation.
Sebastian Johannes Fritsch, Anna Große Siemer, Michael Dreher, Tim-Philipp Simon, Gernot Marx

Quant Imaging Med Surg· May 2024

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Effects of structured protocolized physical therapy on the duration of mechanical ventilation in patients with prolonged weaning.
Johannes Bickenbach, Sebastian Fritsch, Sophia Cosler, Yvonne Simon, Michael Dreher, Tim Philipp Simon

J Crit Care· April 2024

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A Potential Association between Ribonuclease 1 Dynamics in the Blood and the Outcome in COVID-19 Patients.
Elisabeth Zechendorf, Christian Beckers, Nadine Frank, Sandra Kraemer, Carolina Neu, Tim-Philipp Simon

Int J Mol Sci· August 2023

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Standardized pharmacological management of delirium after on-pump cardiac surgery reduces ICU stay and ventilation in a retrospective pre-post study.
Matthias Manfred Deininger, Stefan Schnitzler, Carina Benstoem, Tim-Philipp Simon, Gernot Marx

Sci Rep· March 2023

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Local YB-1, Epo, and EpoR concentrations in fractured bones: results from a porcine model of multiple trauma.
Felix Marius Bläsius, Johannes Greven, Weijun Guo, Eftychios Bolierakis, Zhizhen He, Tim-Philipp Simon

Eur J Med Res· January 2023

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Proenkephalin A and bioactive adrenomedullin are useful for risk prognostication in cardiac surgery.
Aileen Hill, Deborah Bergmann, Janin Schulte, Rashad Zayat, Gernot Marx, Tim-Philipp Simon

Front Cardiovasc Med· January 2023

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The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease.
Elisabeth Zechendorf, Katharina Schröder, Lara Stiehler, Nadine Frank, Christian Beckers, Tim-Philipp Simon

J Clin Med· September 2022

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Standardized porcine unilateral femoral nailing is associated with changes in PMN activation status, rather than aberrant systemic PMN prevalence.
Michel Paul Johan Teuben, Roman Pfeifer, Klemens Horst, Tim-Philipp Simon, Marjolein Heeres

Eur J Trauma Emerg Surg· June 2022

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Haemoglobin value and red blood cell transfusions in prolonged weaning from mechanical ventilation: a retrospective observational study.
Sebastian Johannes Fritsch, Michael Dreher, Tim-Philipp Simon, Gernot Marx, Johannes Bickenbach

BMJ Open Respir Res· June 2022

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Body mass index and leptin levels in serum and cerebrospinal fluid in relation to delayed cerebral ischemia and outcome after aneurysmal subarachnoid hemorrhage.
Michael Veldeman, Miriam Weiss, Tim Philipp Simon, Anke Hoellig, Hans Clusmann

Neurosurg Rev· December 2021

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Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study).
Michael Bauer, Andreas Weyland, Gernot Marx, Frank Bloos, Stephan Weber, Tim Philipp Simon, Philipp Simon

Crit Care Explor· November 2021

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Levels of bioactive adrenomedullin in plasma and cerebrospinal fluid in relation to delayed cerebral ischemia in patients after aneurysmal subarachnoid hemorrhage: A prospective observational study.
Michael Veldeman, Rabia Dogan, Miriam Weiss, Christian Stoppe, Tim Philipp Simon

J Neurol Sci· August 2021

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Hematological and Chemical Profiles in a Porcine Model of Severe Multiple Trauma.
Weijun Guo, Felix Marius Bläsius, Johannes Greven, Peng Luo, Weikang Wang, Tim-Philipp Simon

Eur Surg Res· July 2021

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Efficacy and safety of early target-controlled plasma volume replacement with a balanced gelatine solution versus a balanced electrolyte solution in patients with severe sepsis/septic shock: study protocol, design, and rationale of a prospective, randomized, controlled, double-blind, multicentric, international clinical trial : GENIUS-Gelatine use in ICU and sepsis.
Gernot Marx, Kai Zacharowski, Carole Ichai, Karim Asehnoune, Vladimír Černý, Tim-Philipp Simon

Trials· June 2021

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Six Months Follow-Up of Patients with Invasive Mechanical Ventilation due to COVID-19 Related ARDS.
Ayham Daher, Christian Cornelissen, Niels-Ulrik Hartmann, Paul Balfanz, Annegret Müller, Tim-Philipp Simon

Int J Environ Res Public Health· May 2021

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In-hospital mortality and organ failure after open and endovascular thoraco-abdominal aortic surgery can be predicted by increased levels of circulating dipeptidyl peptidase 3.
Alexander Gombert, Mohammad Barbati, Drosos Kotelis, Tim-Philipp Simon, Thomas Breuer

Eur J Cardiothorac Surg· April 2021

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Prognostic Value of Bioactive Adrenomedullin in Critically Ill Patients with COVID-19 in Germany: An Observational Cohort Study.
Tim-Philipp Simon, Christian Stoppe, Thomas Breuer, Lara Stiehler, Michael Dreher

J Clin Med· April 2021

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Comparison of two empirical prolonged infusion dosing regimens for meropenem in patients with septic shock: A two-center pilot study.
Albrecht Eisert, Christian Lanckohr, Janina Frey, Otto Frey, Sebastian G Wicha, Tim-Philipp Simon

Int J Antimicrob Agents· March 2021

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Macrophage Migration Inhibitory Factor (MIF) Plasma Concentration in Critically Ill COVID-19 Patients: A Prospective Observational Study.
Christian Bleilevens, Josefin Soppert, Adrian Hoffmann, Thomas Breuer, Jürgen Bernhagen, Tim-Philipp Simon

Diagnostics (Basel)· February 2021

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Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical- Approach Combining Experiments and Machine Learning.
Elisabeth Zechendorf, Phillip Vaßen, Jieyi Zhang, Ahmed Hallawa, Antons Martincuks, Tim-Philipp Simon

Front Immunol· December 2020

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Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury: A Randomized Clinical Trial.
Alexander Zarbock, Mira Küllmar, Detlef Kindgen-Milles, Carola Wempe, Joachim Gerss, Tim Philipp Simon, Philipp Simon

JAMA· October 2020

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Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101).
Mahir Karakas, Dominik Jarczak, Martin Becker, Kevin Roedl, Marylyn M Addo, Tim-Philipp Simon

Biomolecules· August 2020

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