Publications by authors named "Timm Danker"

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Symmetrical Bispyridinium Compounds Act as Open Channel Blockers of Cation-Selective Ion Channels.
Yves Haufe, Dominik Loser, Timm Danker, Annette Nicke

ACS Pharmacol Transl Sci· March 2024

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Functional evaluation of epilepsy-associated KCNT1 variants in multiple cellular systems reveals a predominant gain of function impact on channel properties.
Christopher A Hinckley, Zhonghua Zhu, Jen-Hwa Chu, Cynthia Gubbels, Timm Danker

Epilepsia· August 2023

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Toxicological and Safety Pharmacological Profiling of the Anti-Infective and Anti-Inflammatory Peptide Pep19-2.5.
Clemens Möller, Lena Heinbockel, Patrick Garidel, Thomas Gutsmann, Karl Mauss, Timm Danker

Microorganisms· December 2022

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Laser-Induced Action Potential-Like Measurements of Cardiomyocytes on Microelectrode Arrays for Increased Predictivity of Safety Pharmacology.
Jasmin Schaefer, Timm Danker, Karin Gebhardt, Udo Kraushaar

J Vis Exp· September 2022

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Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling.
Dominik Loser, Karin Grillberger, Maria G Hinojosa, Jonathan Blum, Yves Haufe, Timm Danker

Arch Toxicol· December 2021

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Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons.
Dominik Loser, Maria G Hinojosa, Jonathan Blum, Jasmin Schaefer, Markus Brüll, Timm Danker

Arch Toxicol· June 2021

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Human neuronal signaling and communication assays to assess functional neurotoxicity.
Dominik Loser, Jasmin Schaefer, Timm Danker, Clemens Möller, Markus Brüll

Arch Toxicol· January 2021

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Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
James Kramer, Herbert M Himmel, Anders Lindqvist, Sonja Stoelzle-Feix, Khuram W Chaudhary, Timm Danker

Sci Rep· July 2020

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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Timm Danker

Toxicol Appl Pharmacol· May 2020

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Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Timm Danker

Toxicol Appl Pharmacol· May 2020

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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
James Kramer, Herbert M Himmel, Anders Lindqvist, Sonja Stoelzle-Feix, Khuram W Chaudhary, Timm Danker

Sci Rep· March 2020

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Catch and Patch: A Pipette-Based Approach for Automating Patch Clamp That Enables Cell Selection and Fast Compound Application.
Timm Danker, Franziska Braun, Nikole Silbernagl, Elke Guenther

Assay Drug Dev Technol· March 2016

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Early identification of hERG liability in drug discovery programs by automated patch clamp.
Timm Danker, Clemens Möller

Front Pharmacol· September 2014

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Dominant-negative effects of KCNQ2 mutations are associated with epileptic encephalopathy.
Gökce Orhan, Merle Bock, Dorien Schepers, Elena I Ilina, Stephanie Nadine Reichel, Timm Danker

Ann Neurol· March 2014

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Efficient binding of 4/7 α-conotoxins to nicotinic α4β2 receptors is prevented by Arg185 and Pro195 in the α4 subunit.
Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning

Mol Pharmacol· October 2012

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Local administration of DFO-loaded lipid particles improves recovery after end-to-end reconstruction of rat median nerve.
Nektarios Sinis, Frederica Di Scipio, Phillip Schönle, Frank Werdin, Armin Kraus, Timm Danker

Restor Neurol Neurosci· March 2010

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Expansion and differentiation of neural progenitors derived from the human adult enteric nervous system.
Marco Metzger, Petra M Bareiss, Timm Danker, Silvia Wagner, Joerg Hennenlotter

Gastroenterology· December 2009

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An improved electrophysiological method to study peripheral nerve regeneration in rats.
Frank Werdin, Hannes Grüssinger, Patrick Jaminet, Armin Kraus, Theodora Manoli, Timm Danker

J Neurosci Methods· August 2009

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