Publications by authors named "Timo Frensing"

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Reduction of IL-2 fragmentation during manufacturing of a novel immunocytokine by DoE process optimization.
Alina Schneider, Ingo H Gorr, Vincent Larraillet, Timo Frensing, Oliver Popp

Biotechnol Bioeng· October 2019

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Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth.
Tanja Laske, Mandy Bachmann, Melanie Dostert, Alexander Karlas, Dagmar Wirth, Timo Frensing

PLoS Comput Biol· April 2019

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A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome.
Sascha Young Kupke, Dietmar Riedel, Timo Frensing, Pawel Zmora, Udo Reichl

J Virol· February 2019

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Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells.
Timo Frensing, Sascha Y Kupke, Mandy Bachmann, Susanne Fritzsche, Lili E Gallo-Ramirez

Appl Microbiol Biotechnol· August 2016

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Reprint of "Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs.
Tanja Laske, Frank Stefan Heldt, Helene Hoffmann, Timo Frensing, Udo Reichl

Virus Res· June 2016

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Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs.
Tanja Laske, Frank Stefan Heldt, Helene Hoffmann, Timo Frensing, Udo Reichl

Virus Res· February 2016

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Impaired antiviral response of adenovirus-transformed cell lines supports virus replication.
Mandy Bachmann, Theresa Breitwieser, Christoph Lipps, Dagmar Wirth, Ingo Jordan, Timo Frensing

J Gen Virol· February 2016

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Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection.
Frank S Heldt, Sascha Y Kupke, Sebastian Dorl, Udo Reichl, Timo Frensing

Nat Commun· November 2015

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Defective interfering viruses and their impact on vaccines and viral vectors.
Timo Frensing

Biotechnol J· May 2015

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Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production.
Timo Frensing, Antje Pflugmacher, Mandy Bachmann, Britta Peschel, Udo Reichl

Appl Microbiol Biotechnol· November 2014

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Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals.
Frank S Heldt, Timo Frensing, Antje Pflugmacher, Robin Gröpler, Britta Peschel

PLoS Comput Biol· July 2014

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Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles.
Timo Frensing, Frank Stefan Heldt, Antje Pflugmacher, Ilona Behrendt, Ingo Jordan

PLoS One· June 2014

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Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis.
Frank S Heldt, Timo Frensing, Udo Reichl

J Virol· August 2012

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Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Claudius Seitz, Britta Isken, Björn Heynisch, Maria Rettkowski, Timo Frensing

Appl Microbiol Biotechnol· January 2012

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Efficient influenza B virus propagation due to deficient interferon-induced antiviral activity in MDCK cells.
Timo Frensing, Claudius Seitz, Bjoern Heynisch, Corinna Patzina, Georg Kochs

Vaccine· September 2011

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High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state.
Claudius Seitz, Timo Frensing, Dirk Höper, Georg Kochs, Udo Reichl

J Gen Virol· July 2010

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Characterization of a neuregulin-1 gene promoter: positive regulation of type I isoforms by NF-kappaB.
Timo Frensing, Christian Kaltschmidt, Thomas Schmitt-John

Biochim Biophys Acta· February 2008

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