Publications by authors named "Timo Nuijens"

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Traceless enzymatic protein synthesis without ligation sites constraint.
Ruifeng Li, Marcel Schmidt, Tong Zhu, Xinyu Yang, Jing Feng, Timo Nuijens

Natl Sci Rev· May 2022

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From thiol-subtilisin to omniligase: Design and structure of a broadly applicable peptide ligase.
Ana Toplak, Eduardo F Teixeira de Oliveira, Marcel Schmidt, Henriëtte J Rozeboom, Hein J Wijma, Timo Nuijens

Comput Struct Biotechnol J· February 2021

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Chemoenzymatic Synthesis of Linear- and Head-to-Tail Cyclic Peptides Using Omniligase-1.
Marcel Schmidt, Timo Nuijens

Methods Mol Biol· March 2020

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Natural Occurring and Engineered Enzymes for Peptide Ligation and Cyclization.
Timo Nuijens, Ana Toplak, Marcel Schmidt, Antonio Ricci, Walter Cabri

Front Chem· November 2019

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Efficient Enzymatic Cyclization of Disulfide-Rich Peptides by Using Peptide Ligases.
Marcel Schmidt, Yen-Hua Huang, Eduardo F Texeira de Oliveira, Ana Toplak, Hein J Wijma, Timo Nuijens

Chembiochem· June 2019

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Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation.
Dieuwertje E Streefkerk, Marcel Schmidt, Johannes H Ippel, Tilman M Hackeng, Timo Nuijens

Org Lett· April 2019

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A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides.
Gaston J J Richelle, Marcel Schmidt, Hans Ippel, Tilman M Hackeng, Jan H van Maarseveen, Timo Nuijens

Chembiochem· September 2018

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Design of a substrate-tailored peptiligase variant for the efficient synthesis of thymosin-α.
Marcel Schmidt, Ana Toplak, Henriëtte J Rozeboom, Hein J Wijma, Peter J L M Quaedflieg, Timo Nuijens

Org Biomol Chem· January 2018

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Enzyme-catalyzed peptide cyclization.
Marcel Schmidt, Ana Toplak, Peter J L M Quaedflieg, Jan H van Maarseveen, Timo Nuijens

Drug Discov Today Technol· December 2017

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Enzyme-mediated ligation technologies for peptides and proteins.
Marcel Schmidt, Ana Toplak, Peter Jlm Quaedflieg, Timo Nuijens

Curr Opin Chem Biol· June 2017

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Peptide synthesis in neat organic solvents with novel thermostable proteases.
Ana Toplak, Timo Nuijens, Peter J L M Quaedflieg, Bian Wu, Dick B Janssen

Enzyme Microb Technol· June 2015

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Improving the carboxyamidomethyl ester for subtilisin A-catalysed peptide synthesis.
Roseri J A C de Beer, Timo Nuijens, Lotte Wiermans, Peter J L M Quaedflieg, Floris P J T Rutjes

Org Biomol Chem· September 2012

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Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.
Roseri J A C de Beer, Barbara Zarzycka, Helene I V Amatdjais-Groenen, Sander C B Jans, Timo Nuijens

Chembiochem· September 2011

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Enzymatic synthesis of C-terminal arylamides of amino acids and peptides.
Timo Nuijens, Claudia Cusan, John A W Kruijtzer, Dirk T S Rijkers, Rob M J Liskamp

J Org Chem· August 2009

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Selective enrichment of Ser-/Thr-phosphorylated peptides in the presence of Ser-/Thr-glycosylated peptides.
Alex J Poot, Eelco Ruijter, Timo Nuijens, Eef H C Dirksen, Albert J R Heck

Proteomics· December 2006

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