Publications by authors named "Timothy A McCaffrey"

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Blood RNA biomarkers and a point-of-care elastase assay for detecting host immune activation in suspected sepsis: Trajectory matters.
John E Lafleur, Eduard Shaykhinurov, John Perkins, Richard Wargowsky, Kevin Jaatinen, Timothy A McCaffrey

PLoS One· December 2025

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A Point-of-Care Diagnostic Platform for Detecting Host Immune Activation due to Infections: Cytocapture of Biomarkers (CyBIS).
Timothy A McCaffrey, Richard Wargowsky, Kevin Jaatinen, Faisal Al Munajjed, Farris Alqalam

J Med Diagn Methods· January 2025

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Blood RNA Biomarkers Identify Bacterial and Biofilm Coinfections in COVID-19 Intensive Care Patients.
Philip Dela Cruz, Richard Wargowsky, Alberto Gonzalez-Almada, Erick Perez Sifontes, Eduard Shaykhinurov, Timothy A McCaffrey

J Intensive Care Med· November 2024

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COVID-19 point-of-care tests can identify low-antibody individuals: In-depth immunoanalysis of boosting benefits in a healthy cohort.
Michael Mallory, Jennifer E Munt, Tara M Narowski, Izabella Castillo, Edwing Cuadra, Timothy A McCaffrey

Sci Adv· June 2024

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RNAseq of INOCA patients identifies innate, invariant, and acquired immune changes: potential autoimmune microvascular dysfunction.
Kevin Jaatinen, Palak Shah, Ramesh Mazhari, Zane Hayden, Richard Wargowsky, Timothy A McCaffrey

Front Cardiovasc Med· June 2024

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Publisher Correction: Diagnostic accuracy of novel mRNA blood biomarkers of infection to predict outcomes in emergency department patients with undifferentiated abdominal pain.
Andrew C Meltzer, Richard S Wargowsky, Seamus Moran, Tristan Jordan, Ian Toma, Timothy A McCaffrey

Sci Rep· December 2023

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RNAseq profiling of blood from patients with coronary artery disease: Signature of a T cell imbalance.
Timothy A McCaffrey, Ian Toma, Zhaoqing Yang, Richard Katz, Jonathan Reiner

J Mol Cell Cardiol Plus· June 2023

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Longitudinal Analysis of Humoral and Cellular Immune Response Following SARS-CoV-2 Vaccination Supports Utilizing Point-Of-Care Tests to Enhance COVID-19 Booster Uptake.
Michael Mallory, Jennifer E Munt, Tara M Narowski, Izabella Castillo, Edwing Cuadra, Timothy A McCaffrey

medRxiv· April 2023

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Diagnostic accuracy of novel mRNA blood biomarkers of infection to predict outcomes in emergency department patients with undifferentiated abdominal pain.
Andrew C Meltzer, Richard S Wargowsky, Seamus Moran, Tristan Jordan, Ian Toma, Timothy A McCaffrey

Sci Rep· February 2023

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RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections.
Richard Wargodsky, Philip Dela Cruz, John LaFleur, David Yamane, Justin Sungmin Kim, Timothy A McCaffrey

PLoS One· February 2022

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RNAseq analysis of treatment-dependent signaling changes during inflammation in a mouse cutaneous wound healing model.
Georges St Laurent, Ian Toma, Bernd Seilheimer, Konstantin Cesnulevicius, Myron Schultz, Timothy A McCaffrey

BMC Genomics· November 2021

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RNA sequencing of blood in coronary artery disease: involvement of regulatory T cell imbalance.
Timothy A McCaffrey, Ian Toma, Zhaoquing Yang, Richard Katz, Jonathan Reiner

BMC Med Genomics· September 2021

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Biomarker discovery in attention deficit hyperactivity disorder: RNA sequencing of whole blood in discordant twin and case-controlled cohorts.
Timothy A McCaffrey, Georges St Laurent, Dmitry Shtokalo, Denis Antonets, Yuri Vyatkin

BMC Med Genomics· October 2020

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Benchmark Evaluation of True Single Molecular Sequencing to Determine Cystic Fibrosis Airway Microbiome Diversity.
Andrea Hahn, Matthew L Bendall, Keylie M Gibson, Hollis Chaney, Iman Sami, Timothy A McCaffrey

Front Microbiol· May 2018

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Predictors of high on-aspirin platelet reactivity in elderly patients with coronary artery disease.
J W Zhang, W W Liu, Timothy A McCaffrey, X Q He, W Y Liang

Clin Interv Aging· March 2018

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An efficient concordant integrative analysis of multiple large-scale two-sample expression data sets.
Yinglei Lai, Fanni Zhang, Tapan K Nayak, Reza Modarres, Norman H Lee, Timothy A McCaffrey

Bioinformatics· December 2017

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Validation of aspirin response-related transcripts in patients with coronary artery disease and preliminary investigation on CMTM5 function.
J W Zhang, T F Liu, X H Chen, W Y Liang, X R Feng, Timothy A McCaffrey

Gene· August 2017

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Deep Sequencing Transcriptome Analysis of Murine Wound Healing: Effects of a Multicomponent, Multitarget Natural Product Therapy-Tr14.
Georges St Laurent, Bernd Seilheimer, Michael Tackett, Jianhua Zhou, Dmitry Shtokalo, Timothy A McCaffrey

Front Mol Biosci· August 2017

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Detecting discordance enrichment among a series of two-sample genome-wide expression data sets.
Yinglei Lai, Fanni Zhang, Tapan K Nayak, Reza Modarres, Norman H Lee, Timothy A McCaffrey

BMC Genomics· January 2017

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Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes.
Lakhmir S Chawla, Ian Toma, Danielle Davison, Khashayar Vaziri, Juliet Lee, Timothy A McCaffrey

BMC Med Genomics· July 2016

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Functional annotation of the vlinc class of non-coding RNAs using systems biology approach.
Georges St Laurent, Yuri Vyatkin, Denis Antonets, Maxim Ri, Yao Qi, Timothy A McCaffrey

Nucleic Acids Res· April 2016

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Metataxonomic and Metagenomic Approaches vs. Culture-Based Techniques for Clinical Pathology.
Sarah K Hilton, Eduardo Castro-Nallar, Marcos Pérez-Losada, Ian Toma, Timothy A McCaffrey

Front Microbiol· April 2016

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Comparison between urinary 11-dehydrothromboxane B2 detection and platelet Light Transmission Aggregometry (LTA) assays for evaluating aspirin response in elderly patients with coronary artery disease.
Tengfei Liu, Jingwei Zhang, Xiahuan Chen, Xueru Feng, Sidney W Fu, Timothy A McCaffrey

Gene· October 2015

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Concordant integrative gene set enrichment analysis of multiple large-scale two-sample expression data sets.
Yinglei Lai, Fanni Zhang, Tapan K Nayak, Reza Modarres, Norman H Lee, Timothy A McCaffrey

BMC Genomics· November 2014

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Single-molecule long-read 16S sequencing to characterize the lung microbiome from mechanically ventilated patients with suspected pneumonia.
Ian Toma, Marc O Siegel, John Keiser, Anna Yakovleva, Alvin Kim, Timothy A McCaffrey

J Clin Microbiol· November 2014

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