Publications by authors named "Timothy A Thornton"

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Multiple-testing corrections in case-control studies using identity-by-descent segments.
Seth D Temple, Nicola H Chapman, Seung Hoan Choi, Anita L DeStefano, Timothy A Thornton

bioRxiv· July 2025

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Adjusting for principal components can induce collider bias in genome-wide association studies.
Kelsey E Grinde, Brian L Browning, Alexander P Reiner, Timothy A Thornton, Sharon R Browning

PLoS Genet· December 2024

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Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank.
Sheila M Gaynor, Tyler Joseph, Xiaodong Bai, Yuxin Zou, Boris Boutkov, Timothy A Thornton

Nat Genet· November 2024

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Admixture Mapping of Chronic Kidney Disease and Risk Factors in Hispanic/Latino Individuals From Central America Country of Origin.
Andrea R V R Horimoto, Quan Sun, James P Lash, Martha L Daviglus, Jianwen Cai, Timothy A Thornton

Circ Genom Precis Med· August 2024

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Adjusting for principal components can induce spurious associations in genome-wide association studies in admixed populations.
Kelsey E Grinde, Brian L Browning, Alexander P Reiner, Timothy A Thornton, Sharon R Browning

bioRxiv· April 2024

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Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI.
Quan Sun, Bryce T Rowland, Jiawen Chen, Anna V Mikhaylova, Christy Avery, Timothy A Thornton

Nat Commun· February 2024

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Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman, Joelle Mbatchou, Timothy A Thornton

Nature· February 2024

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Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman, Joelle Mbatchou, Timothy A Thornton

Nature· October 2023

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X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease.
Thiago P Leal, Shilpa C Rao, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Timothy A Thornton

Mov Disord· September 2023

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Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations.
Andrea R V R Horimoto, Lisa A Boyken, Elizabeth E Blue, Kelsey E Grinde, Rafael A Nafikov, Timothy A Thornton

HGG Adv· July 2023

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X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson Disease.
Thiago P Leal, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Miguel Inca-Martinez, Timothy A Thornton

medRxiv· February 2023

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Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease.
Yann Le Guen, Ana-Caroline Raulin, Mark W Logue, Richard Sherva, Michael E Belloy, Timothy A Thornton

JAMA· February 2023

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Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort.
Douglas P Loesch, Andrea R V R Horimoto, Elif Irem Sarihan, Miguel Inca-Martinez, Emily Mason, Timothy A Thornton

Parkinsonism Relat Disord· September 2022

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Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
Xiaowei Hu, Dandi Qiao, Wonji Kim, Matthew Moll, Pallavi P Balte, Timothy A Thornton

Am J Hum Genet· May 2022

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Protein prediction for trait mapping in diverse populations.
Ryan Schubert, Elyse Geoffroy, Isabelle Gregga, Ashley J Mulford, Francois Aguet, Timothy A Thornton

PLoS One· March 2022

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Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States.
Andrea R V R Horimoto, Diane Xue, Jianwen Cai, James P Lash, Martha L Daviglus, Timothy A Thornton

J Am Soc Nephrol· January 2022

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Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.
Nels C Olson, Laura M Raffield, Anne H Moxley, Tyne W Miller-Fleming, Paul L Auer, Timothy A Thornton

Circ Genom Precis Med· December 2021

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Genome-wide association study in the Taiwan Biobank identifies four novel genes for human height: NABP2, RASA2, RNF41 and SLC39A5.
Eugene Lin, Shih-Jen Tsai, Po-Hsiu Kuo, Yu-Li Liu, Albert C Yang, Timothy A Thornton

Hum Mol Genet· November 2021

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Nicotine metabolism and its association with CYP2A6 genotype among Indigenous people in Alaska who smoke.
Krista R Schaefer, Jaedon P Avey, Michael R Todd, Julie A Beans, Denise A Dillard, Timothy A Thornton

Clin Transl Sci· November 2021

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Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
Anna V Mikhaylova, Caitlin P McHugh, Linda M Polfus, Laura M Raffield, Meher Preethi Boorgula, Timothy A Thornton

Am J Hum Genet· October 2021

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Characterizing the Genetic Architecture of Parkinson's Disease in Latinos.
Douglas P Loesch, Andrea R V R Horimoto, Karl Heilbron, Elif I Sarihan, Miguel Inca-Martinez, Timothy A Thornton

Ann Neurol· September 2021

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Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics.
Andréa R V R Horimoto, Diane Xue, Timothy A Thornton, Elizabeth E Blue

Alzheimers Res Ther· July 2021

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Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants.
Maggie A Stanislawski, Leslie A Lange, Laura M Raffield, Neil A Zakai, Mariah Meyer, Timothy A Thornton

Arterioscler Thromb Vasc Biol· June 2021

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Variant-specific inflation factors for assessing population stratification at the phenotypic variance level.
Tamar Sofer, Xiuwen Zheng, Cecelia A Laurie, Stephanie M Gogarten, Jennifer A Brody, Timothy A Thornton

Nat Commun· June 2021

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In Vivo Functional Effects of a Novel and Common Variant in the Yup'ik Alaska Native Population.
Lindsay M Henderson, Scarlett E Hopkins, Bert B Boyer, Timothy A Thornton, Allan E Rettie

Drug Metab Dispos· May 2021

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