Publications by authors named "Timothy Back"

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Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function.
Md Masud Alam, De Yang, Xiao-Qing Li, Jia Liu, Timothy Carrel Back

Cell Rep· January 2022

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Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins.
Poonam Tewary, Alan D Brooks, Ya-Ming Xu, E M Kithsiri Wijeratne, Ashley L Babyak, Timothy C Back

Cancer Res· June 2021

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Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model.
Robert Y S Cheng, Nimit L Patel, Timothy Back, Debashree Basudhar, Veena Somasundaram

J Vis Exp· March 2020

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Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations.
Emilee Senkevitch, Wenqing Li, Julie A Hixon, Caroline Andrews, Sarah D Cramer, Timothy Back

Oncotarget· April 2018

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LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Anthony J Scarzello, Qun Jiang, Timothy Back, Hien Dang, Deborah Hodge

Gut· October 2016

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Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy.
Jeff J Subleski, Anthony J Scarzello, W Gregory Alvord, Qun Jiang, Jimmy K Stauffer, Timothy Back

J Hepatol· November 2015

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Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.
Noriho Iida, Amiran Dzutsev, C Andrew Stewart, Loretta Smith, Nicolas Bouladoux, Timothy Back

Science· November 2013

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The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.
Zuoxiang Xiao, Qun Jiang, Jami Willette-Brown, Sichuan Xi, Feng Zhu, Timothy Back

Cancer Cell· April 2013

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Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.
Naotake Funamizu, Chaoxin Hu, Curtis Lacy, Aaron Schetter, Geng Zhang, Timothy C Back

Int J Cancer· February 2013

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Systemic IL-12 administration alters hepatic dendritic cell stimulation capabilities.
Tim Chan, Timothy C Back, Jeffrey J Subleski, Jonathan M Weiss, John R Ortaldo

PLoS One· August 2012

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High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery.
Jimmy K Stauffer, Rimas J Orentas, Erin Lincoln, Tahira Khan, Rosalba Salcedo, Timothy C Back

Cancer Invest· June 2012

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mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.
Qun Jiang, Jonathan M Weiss, Timothy Back, Tim Chan, John R Ortaldo

Cancer Res· June 2011

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Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors.
Jimmy K Stauffer, Anthony J Scarzello, Jesper B Andersen, Rachel L De Kluyver, Timothy C Back

Cancer Res· April 2011

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TCR-dependent and -independent activation underlie liver-specific regulation of NKT cells.
Jeff J Subleski, Veronica L Hall, Thomas B Wolfe, Anthony J Scarzello, Jonathan M Weiss, Timothy C Back

J Immunol· January 2011

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Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment.
Jonathan M Weiss, Timothy C Back, Anthony J Scarzello, Jeff J Subleski, Veronica L Hall

Proc Natl Acad Sci U S A· November 2009

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Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow.
Rosalba Salcedo, Julie A Hixon, Jimmy K Stauffer, Rashmi Jalah, Alan D Brooks, Timothy C Back

J Immunol· April 2009

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Nitric oxide is a key component in inflammation-accelerated tumorigenesis.
S Perwez Hussain, Peijun He, Jeffery Subleski, Lorne J Hofseth, Glenwood E Trivers, Timothy Back

Cancer Res· September 2008

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In vivo regulation of experimental autoimmune encephalomyelitis by NK cells: alteration of primary adaptive responses.
Robin Winkler-Pickett, Howard A Young, James M Cherry, John Diehl, John Wine, Timothy Back

J Immunol· April 2008

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Modulation of lymphocyte function with inhibitory CD2: loss of NK and NKT cells.
John R Ortaldo, Anna Mason, Jami Willette-Brown, Frank W Ruscetti, John Wine, Timothy Back

Cell Immunol· September 2007

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IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy.
Vanessa Berner, Haiyan Liu, Qing Zhou, Kory L Alderson, Kai Sun, Timothy C Back

Nat Med· March 2007

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Enhanced antitumor response by divergent modulation of natural killer and natural killer T cells in the liver.
Jeff J Subleski, Veronica L Hall, Timothy C Back, John R Ortaldo, Robert H Wiltrout

Cancer Res· November 2006

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Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression.
Lynnette Shorts, Jonathan M Weiss, Jong-Keuk Lee, Lisbeth A Welniak, Jeffrey Subleski, Timothy Back

J Immunol· June 2006

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Multicolor fluorescence-based approaches for imaging cytokine-induced alterations in the neovascularization, growth, metastasis, and apoptosis of murine neuroblastoma tumors.
Jimmy K Stauffer, Tahira Khan, Rosalba Salcedo, Julie A Hixon, Erin Lincoln, Timothy C Back

J Immunother· May 2006

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Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors.
Tahira Khan, Jimmy K Stauffer, Rebecca Williams, Julie A Hixon, Rosalba Salcedo, Timothy C Back

J Immunol· May 2006

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Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma.
Tahira Khan, Julie A Hixon, Jimmy K Stauffer, Erin Lincoln, Timothy C Back

J Natl Cancer Inst· February 2006

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