Publications by authors named "Timothy Cairns"

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The multipurpose cell factory Aspergillus niger can be engineered to produce hydroxylated collagen.
Tom Morris, Friederike Gerstl, Sascha Jung, Timothy C Cairns, Vera Meyer

Biotechnol Biofuels Bioprod· August 2025

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MstH Is the Major High-Affinity Glucose Transporter with Pleiotropic Roles in Carbon Utilization Regulation and Citric Acid Production in .
Xiaomei Zheng, Meiling Chen, Peng Du, Timothy C Cairns, Lihui Zhang

J Agric Food Chem· May 2025

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Uncovering the transcriptional landscape of Fomes fomentarius during fungal-based material production through gene co-expression network analysis.
Timothy Cairns, Carsten Freidank-Pohl, Anna Sofia Birke, Carmen Regner, Sascha Jung

Fungal Biol Biotechnol· February 2025

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Breaking down barriers: comprehensive functional analysis of the Aspergillus niger chitin synthase repertoire.
Lars Barthel, Timothy Cairns, Sven Duda, Henri Müller, Birgit Dobbert

Fungal Biol Biotechnol· March 2024

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Genome-wide transcription landscape of citric acid producing in response to glucose gradient.
Xiaomei Zheng, Peng Du, Kaiyue Gao, Yimou Du, Timothy C Cairns

Front Bioeng Biotechnol· October 2023

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Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in Aspergillus niger.
Timothy C Cairns, Tom de Kanter, Xiaomei Z Zheng, Ping Zheng, Jibin Sun

Biotechnol Biofuels Bioprod· June 2023

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Quantitative phenotypic screens of Aspergillus niger mutants in solid and liquid culture.
Timothy Cairns, Xiaomei Zheng, Claudia Feurstein, Ping Zheng, Jibin Sun

STAR Protoc· December 2022

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Protocol for gene characterization in Aspergillus niger using 5S rRNA-CRISPR-Cas9-mediated Tet-on inducible promoter exchange.
Xiaomei Zheng, Timothy Cairns, Ping Zheng, Vera Meyer, Jibin Sun

STAR Protoc· December 2022

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Comprehensively dissecting the hub regulation of PkaC on high-productivity and pellet macromorphology in citric acid producing Aspergillus niger.
Xiaomei Zheng, Timothy C Cairns, Xiaomei Ni, Lihui Zhang, Huanhuan Zhai

Microb Biotechnol· June 2022

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A Library of Chassis Strains for Morphology Engineering Connects Strain Fitness and Filamentous Growth With Submerged Macromorphology.
Timothy C Cairns, Xiaomei Zheng, Claudia Feurstein, Ping Zheng, Jibin Sun

Front Bioeng Biotechnol· January 2022

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Filamentous fungal applications in biotechnology: a combined bibliometric and patentometric assessment.
Pamina Füting, Lars Barthel, Timothy C Cairns, Heiko Briesen, Stefan Schmideder

Fungal Biol Biotechnol· December 2021

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Beyond the Biosynthetic Gene Cluster Paradigm: Genome-Wide Coexpression Networks Connect Clustered and Unclustered Transcription Factors to Secondary Metabolic Pathways.
Min Jin Kwon, Charlotte Steiniger, Timothy C Cairns, Jennifer H Wisecaver, Abigail L Lind

Microbiol Spectr· October 2021

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Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering.
Vera Meyer, Timothy Cairns, Lars Barthel, Rudibert King, Philipp Kunz

Fungal Biol Biotechnol· August 2021

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Something old, something new: challenges and developments in Aspergillus niger biotechnology.
Timothy C Cairns, Lars Barthel, Vera Meyer

Essays Biochem· July 2021

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Turning Inside Out: Filamentous Fungal Secretion and Its Applications in Biotechnology, Agriculture, and the Clinic.
Timothy C Cairns, Xiaomei Zheng, Ping Zheng, Jibin Sun, Vera Meyer

J Fungi (Basel)· July 2021

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Disruption or reduced expression of the orotidine-5'-decarboxylase gene pyrG increases citric acid production: a new discovery during recyclable genome editing in Aspergillus niger.
Lihui Zhang, Xiaomei Zheng, Timothy C Cairns, Zhidan Zhang, Depei Wang

Microb Cell Fact· March 2020

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The ORFeome: A Functional Genomics Community Resource.
Yogesh Chaudhari, Timothy C Cairns, Yaadwinder Sidhu, Victoria Attah, Graham Thomas

Mol Plant Microbe Interact· December 2019

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Correction to: Functional exploration of co-expression networks identifies a nexus for modulating protein and citric acid titres in submerged culture.
Timothy C Cairns, Claudia Feurstein, Xiaomei Zheng, Li Hui Zhang, Ping Zheng

Fungal Biol Biotechnol· December 2019

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Functional exploration of co-expression networks identifies a nexus for modulating protein and citric acid titres in submerged culture.
Timothy C Cairns, Claudia Feurstein, Xiaomei Zheng, Li Hui Zhang, Ping Zheng

Fungal Biol Biotechnol· November 2019

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5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in .
Xiaomei Zheng, Ping Zheng, Kun Zhang, Timothy C Cairns, Vera Meyer

ACS Synth Biol· July 2019

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A quantitative image analysis pipeline for the characterization of filamentous fungal morphologies as a tool to uncover targets for morphology engineering: a case study using in .
Timothy C Cairns, Claudia Feurstein, Xiaomei Zheng, Ping Zheng, Jibin Sun

Biotechnol Biofuels· June 2019

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Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories.
Timothy C Cairns, Xiaomei Zheng, Ping Zheng, Jibin Sun, Vera Meyer

Biotechnol Biofuels· April 2019

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Comprehensive Improvement of Sample Preparation Methodologies Facilitates Dynamic Metabolomics of Aspergillus niger.
Xiaomei Zheng, Jiandong Yu, Timothy C Cairns, Lihui Zhang, Zhidan Zhang

Biotechnol J· March 2019

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How a fungus shapes biotechnology: 100 years of research.
Timothy C Cairns, Corrado Nai, Vera Meyer

Fungal Biol Biotechnol· May 2018

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Conditional Expression of the Small GTPase ArfA Impacts Secretion, Morphology, Growth, and Actin Ring Position in .
Markus R M Fiedler, Timothy C Cairns, Oliver Koch, Christin Kubisch, Vera Meyer

Front Microbiol· May 2018

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