Publications by authors named "Timothy D Folsom"

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Clinical manufacture of CRISPR/Cas9-based cytokine-induced SH2 protein knock-out tumor-infiltrating lymphocytes for gastrointestinal cancers.
Matthew J Johnson, Darin Sumstad, Timothy D Folsom, Nicholas J Slipek, Anthony P DeFeo

Cytotherapy· October 2025

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Impaired Aggrephagy, Interrupted Vesicular Trafficking, and Cellular Stress, Lead to Protein Aggregation, and Synaptic Dysfunction in Cerebellum of Children and Adults with Idiopathic Autism.
S Hossein Fatemi, Timothy D Folsom, Arthur Eschenlauer, Thierry Chekouo

Cerebellum· August 2025

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Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial.
Emil Lou, Modassir S Choudhry, Timothy K Starr, Timothy D Folsom, Jason Bell

Lancet Oncol· May 2025

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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates.
Matthew J Johnson, Anthony P DeFeo, Nicholas J Slipek, Timothy D Folsom, Tom Henley

J Vis Exp· May 2025

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Quantitative proteomics of dorsolateral prefrontal cortex reveals an early pattern of synaptic dysmaturation in children with idiopathic autism.
S Hossein Fatemi, Arthur Eschenlauer, Justin Aman, Timothy D Folsom, Thierry Chekouo

Cereb Cortex· May 2024

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Early Chronic Fluoxetine Treatment of Ts65Dn Mice Rescues Synaptic Vesicular Deficits and Prevents Aberrant Proteomic Alterations.
S Hossein Fatemi, Elysabeth D Otte, Timothy D Folsom, Arthur C Eschenlauer, Randall J Roper

Genes (Basel)· April 2024

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Quantitative proteomics of forebrain subcellular fractions in fragile X mental retardation 1 knockout mice following acute treatment with 2-Methyl-6-(phenylethynyl)pyridine: Relevance to developmental study of schizophrenia.
Timothy D Folsom, LeeAnn Higgins, Todd W Markowski, Timothy J Griffin, S Hossein Fatemi

Synapse· January 2019

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Metabotropic glutamate receptor 5 tracer [F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study.
S Hossein Fatemi, Dean F Wong, James R Brašić, Hiroto Kuwabara, Anil Mathur, Timothy D Folsom

Cerebellum Ataxias· February 2018

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Altered subcellular localization of fragile X mental retardation signaling partners and targets in superior frontal cortex of individuals with schizophrenia.
S Hossein Fatemi, Timothy D Folsom, Paul D Thuras

Neuroreport· November 2017

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GABA and GABA receptor dysregulation in superior frontal cortex of subjects with schizophrenia and bipolar disorder.
S Hossein Fatemi, Timothy D Folsom, Paul D Thuras

Synapse· July 2017

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The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum.
S Hossein Fatemi, Timothy D Folsom, Stephanie B Liesch, Rachel E Kneeland, Mahtab Karkhane Yousefi

J Neurosci Res· May 2017

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Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder.
Richard E Frye, Manuel F Casanova, S Hossein Fatemi, Timothy D Folsom, Teri J Reutiman

Front Neurosci· May 2016

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GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.
S Hossein Fatemi, Timothy D Folsom

Schizophr Res· September 2015

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Protein expression of targets of the FMRP regulon is altered in brains of subjects with schizophrenia and mood disorders.
Timothy D Folsom, Paul D Thuras, S Hossein Fatemi

Schizophr Res· July 2015

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Existence of monomer and dimer forms of mGluR5, under reducing conditions in studies of postmortem brain in various psychiatric disorders.
S Hossein Fatemi, Timothy D Folsom

Schizophr Res· September 2014

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Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism.
S Hossein Fatemi, Teri J Reutiman, Timothy D Folsom, Oyvind G Rustan, Robert J Rooney

J Autism Dev Disord· August 2014

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Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling.
Oyvind G Rustan, Timothy D Folsom, Mahtab K Yousefi, S Hossein Fatemi

Mol Autism· November 2013

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A review of traditional and novel treatments for seizures in autism spectrum disorder: findings from a systematic review and expert panel.
Richard E Frye, Daniel Rossignol, Manuel F Casanova, Gregory L Brown, Victoria Martin, Timothy D Folsom

Front Public Health· September 2013

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Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex.
S Hossein Fatemi, Timothy D Folsom, Rachel E Kneeland, Mahtab K Yousefi, Stephanie B Liesch

Mol Autism· June 2013

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The involvement of Reelin in neurodevelopmental disorders.
Timothy D Folsom, S Hossein Fatemi

Neuropharmacology· May 2013

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Antismoking and potential antipsychotic effects of varenicline in subjects with schizophrenia or schizoaffective disorder: a double-blind placebo and bupropion-controlled study.
S Hossein Fatemi, Mahtab K Yousefi, Rachel E Kneeland, Stephanie B Liesch, Timothy D Folsom

Schizophr Res· May 2013

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Comparative gene expression study of the chronic exposure to clozapine and haloperidol in rat frontal cortex.
S Hossein Fatemi, Timothy D Folsom, Teri J Reutiman, Jessica Novak, Rachelanne H Engel

Schizophr Res· February 2012

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A Review of Varenicline's Efficacy and Tolerability in Smoking Cessation Studies in Subjects with Schizophrenia.
Mahtab Karkhane Yousefi, Timothy D Folsom, S Hossein Fatemi

J Addict Res Ther· December 2011

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Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism.
S Hossein Fatemi, Timothy D Folsom, Rachel E Kneeland, Stephanie B Liesch

Anat Rec (Hoboken)· October 2011

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Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study.
S Hossein Fatemi, Timothy D Folsom

Mol Autism· May 2011

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