Publications by authors named "Timothy D Heath"

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Durable multitransgene expression in vivo using systemic, nonviral DNA delivery.
Chakkrapong Handumrongkul, Alice L Ye, Stephen A Chmura, Liliana Soroceanu, Marissa Mack, Timothy D Heath

Sci Adv· November 2019

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Postoperative Analgesia Provided by Liposomal Hydromorphone in Client-Owned Dogs Undergoing Limb Amputation.
Lisa Krugner-Higby, Lesley J Smith, Brynn Schmidt, Paulo V Steagall, Carolyn Brown, Timothy D Heath

J Am Anim Hosp Assoc· August 2016

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A Novel Loading Method for Doxycycline Liposomes for Intracellular Drug Delivery: Characterization of In Vitro and In Vivo Release Kinetics and Efficacy in a J774A.1 Cell Line Model of Mycobacterium smegmatis Infection.
Rebekah K Franklin, Sarah A Marcus, Adel M Talaat, Butch K KuKanich, Ruth Sullivan, Timothy D Heath

Drug Metab Dispos· August 2015

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Pharmacokinetics of ammonium sulfate gradient loaded liposome-encapsulated oxymorphone and hydromorphone in healthy dogs.
Lesley J Smith, Butch K Kukanich, Lisa A Krugner-Higby, Brynn H Schmidt, Timothy D Heath

Vet Anaesth Analg· September 2013

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Pharmacokinetics of long-acting nalbuphine decanoate after intramuscular administration to Hispaniolan Amazon parrots (Amazona ventralis).
David Sanchez-Migallon Guzman, Butch KuKanich, Timothy D Heath, Lisa A Krugner-Higby, Steven A Barker

Am J Vet Res· February 2013

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Antinociceptive effects of long-acting nalbuphine decanoate after intramuscular administration to Hispaniolan Amazon parrots (Amazona ventralis).
David Sanchez-Migallon Guzman, Jana M Braun, Paulo V M Steagall, Nicholas S Keuler, Timothy D Heath

Am J Vet Res· February 2013

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Pharmacokinetics and behavioral effects of liposomal hydromorphone suitable for perioperative use in rhesus macaques.
Lisa Krugner-Higby, Butch KuKanich, Brynn Schmidt, Timothy D Heath, Carolyn Brown

Psychopharmacology (Berl)· August 2011

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Experimental pharmacodynamics and analgesic efficacy of liposome-encapsulated hydromorphone in dogs.
Lisa Krugner-Higby, Lesley Smith, Brynn Schmidt, Laura Wunsch, Andrea Smetana, Timothy D Heath

J Am Anim Hosp Assoc· August 2011

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Epidural administration of liposome-encapsulated hydromorphone provides extended analgesia in a rodent model of stifle arthritis.
Jennifer R Schmidt, Lisa Krugner-Higby, Timothy D Heath, Ruth Sullivan, Lesley J Smith

J Am Assoc Lab Anim Sci· July 2011

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A mathematical relationship for hydromorphone loading into liposomes with trans-membrane ammonium sulfate gradients.
Sheng Tu, Tamara McGinnis, Lisa Krugner-Higby, Timothy D Heath

J Pharm Sci· June 2010

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Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model.
Eric J Wagner, Carolyn S Brown, Jennifer R Mather, Cecilia Scholcoff, Lisa Krugner-Higby, Timothy D Heath

J Pharm Sci· April 2010

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Analgesic effects of carprofen and liposome-encapsulated butorphanol tartrate in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis.
Joanne R Paul-Murphy, Kurt K Sladky, Lisa A Krugner-Higby, Ben R Stading, Julia M Klauer, Timothy D Heath

Am J Vet Res· October 2009

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Evaluation of liposome-encapsulated butorphanol tartrate for alleviation of experimentally induced arthritic pain in green-cheeked conures (Pyrrhura molinae).
Joanne R Paul-Murphy, Lisa A Krugner-Higby, Renee L Tourdot, Kurt K Sladky, Julia M Klauer, Timothy D Heath

Am J Vet Res· October 2009

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Pharmacokinetics and behavioral effects of an extended-release, liposome-encapsulated preparation of oxymorphone in rhesus macaques.
Lisa Krugner-Higby, Butch KuKanich, Brynn Schmidt, Timothy D Heath, Carolyn Brown

J Pharmacol Exp Ther· July 2009

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Liposome dependent delivery of S-adenosyl methionine to cells by liposomes: a potential treatment for liver disease.
Eric J Wagner, Lisa Krugner-Higby, Timothy D Heath

J Pharm Sci· February 2009

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A single dose of liposome-encapsulated hydromorphone provides extended analgesia in a rat model of neuropathic pain.
Lesley J Smith, Janice R Valenzuela, Lisa A Krugner-Higby, Carolyn Brown, Timothy D Heath

Comp Med· December 2006

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Serum concentrations and analgesic effects of liposome-encapsulated and standard butorphanol tartrate in parrots.
Kurt K Sladky, Lisa Krugner-Higby, Elizabeth Meek-Walker, Timothy D Heath, Joanne Paul-Murphy

Am J Vet Res· May 2006

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Methodology and experimental design for the study of liposome-dependent drugs.
Timothy D Heath

Methods Enzymol· August 2005

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Suppression of cold ischemic injury in stored kidneys by the antimicrobial peptide bactenecin.
Jonathan F McAnulty, John D Foley, Ted W Reid, Timothy D Heath, Kenneth R Waller

Cryobiology· December 2004

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Evaluation of liposome-encapsulated oxymorphone hydrochloride in mice after splenectomy.
Melanee D Clark, Lisa Krugner-Higby, Lesley J Smith, Timothy D Heath, Krystal L Clark

Comp Med· October 2004

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The effect of liposome size on the final lipid/DNA ratio of cationic lipoplexes.
Elisabete Gonçalves, Robert J Debs, Timothy D Heath

Biophys J· March 2004

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Liposome-encapsulated oxymorphone hydrochloride provides prolonged relief of postsurgical visceral pain in rats.
Lisa Krugner-Higby, Lesley Smith, Melanee Clark, Timothy D Heath, Elizabeth Dahly

Comp Med· June 2003

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A single dose of liposome-encapsulated oxymorphone or morphine provides long-term analgesia in an animal model of neuropathic pain.
Lesley J Smith, Lisa Krugner-Higby, Melanee Clark, Allyson Wendland, Timothy D Heath

Comp Med· June 2003

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Cell association of liposomes with high fluid anionic phospholipid content is mediated specifically by LDL and its receptor, LDLr.
Ketan Amin, Kishor M Wasan, Ralph M Albrecht, Timothy D Heath

J Pharm Sci· May 2002

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Strain-based genetic differences regulate the efficiency of systemic gene delivery as well as expression.
Yong Liu, H Denny Liggitt, Steven Dow, Chakkrapong Handumrongkul, Timothy D Heath

J Biol Chem· February 2002

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