Publications by authors named "Timothy D McHugh"

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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.
David S Hui, Esam I Azhar, Tariq A Madani, Francine Ntoumi, Richard Kock, Osman Dar, Giuseppe Ippolito, Timothy D Mchugh, Ziad A Memish, Christian Drosten

Int J Infect Dis· February 2020

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Systematic review and meta-analysis of humoral immunity proteins and mortality in sepsis.
Antoine Villa, Fiona Dewar, Walter Pisciotta, Ankit Rai, Sven Kerneis, Timothy D McHugh

Crit Care· December 2025

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Sutezolid in combination with bedaquiline, delamanid, and moxifloxacin for pulmonary tuberculosis (PanACEA-SUDOCU-01): a prospective, open-label, randomised, phase 2b dose-finding trial.
Norbert Heinrich, Christina Manyama, Simon E Koele, Stellah Mpagama, Francis Mhimbira, Timothy D McHugh

Lancet Infect Dis· November 2025

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Delpazolid in combination with bedaquiline, delamanid, and moxifloxacin for pulmonary tuberculosis (PanACEA-DECODE-01): a prospective, randomised, open-label, phase 2b, dose-finding trial.
Lilian Tina Minja, Isabella van der Feltz, Christina Manyama, Stellah Mpagama, Francis Mhimbira, Timothy D McHugh

Lancet Infect Dis· November 2025

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Pharmacodynamic interactions among meropenem ciprofloxacin and gentamicin in an in-vitro model.
Zahra Sadouki, Emmanuel Q Wey, Liam Read, Mark Bayliss, Alan Noel, Timothy D McHugh

Sci Rep· November 2025

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An assessment of molecular diagnosis of tuberculosis and multi-drug resistant tuberculosis testing and quality assessment: findings of an international survey.
Jim F Huggett, Daniel Evans, Denise M O'Sullivan, Katell Peoc'h, Helia Bakhshi-Nejad, Timothy D McHugh

Clin Chem Lab Med· October 2025

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Correction: A pragmatic pipeline for drug resistance and lineage identification in Mycobacterium tuberculosis using whole genome sequencing.
Linzy Elton, Alp Aydin, Neil Stoker, Sylvia Rofael, Letícia Muraro Wildner, Timothy D McHugh

PLOS Glob Public Health· September 2025

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A metagenomic approach to One Health surveillance of antimicrobial resistance in a UK veterinary centre.
Linzy Elton, Alonso Dupuy Mateos, Siân Marie Frosini, Rosanne Jepson, Sylvia Rofael, Timothy D McHugh

Microb Genom· September 2025

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Cardiac safety of bedaquiline, delamanid and moxifloxacin co-administered with or without varying doses of sutezolid or delpazolid for the treatment of drug-susceptible TB.
Simon E Koele, Krista Stoycheva, Cyprian Mtweve, Christina Manyama, Stellah Mpagama, Timothy D McHugh

J Antimicrob Chemother· August 2025

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Population pharmacokinetics and exposure-response relationship of the antituberculosis drug BTZ-043.
Simon E Koele, Norbert Heinrich, Veronique R De Jager, Julia Dreisbach, Patrick P J Phillips, Timothy D Mchugh

J Antimicrob Chemother· May 2025

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Drug-resistant tuberculosis profiles among patients presenting at the antituberculosis center of Brazzaville, Republic of Congo.
Breli Bonheur Ngouama, Jean Claude Djontu, Darrel Ornelle Elion Assiana, Freisnel Hermeland Mouzinga, Mita Naomie Merveille Dello, Timothy D McHugh

Ann Clin Microbiol Antimicrob· May 2025

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C-reactive protein and association with disease severity in hospitalized adult patients with Lassa fever in Nigeria.
Ebenezer Oseremen Dic-Ijiewere, Danny Asogun, Festus Oloruntoba Okojie, Adoghe Patricia Omono, Okpunu Eseoleleti Christopher, Timothy D McHugh

IJID Reg· March 2025

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Plasma zinc and selenium levels in adult inpatients with Lassa fever in Nigeria: A case-controlled study.
Ebenezer Oseremen Dic-Ijiewere, Danny Asogun, Festus Oloruntoba Okojie, Adoghe Patricia Omono, Okpunu Eseoleleti Christopher, Timothy D McHugh

IJID Reg· March 2025

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Undiagnosed burden of latent tuberculosis, active tuberculosis and tuberculosis-HIV co-infections in Africa-status quo, needs, priorities, and opportunities.
Nathan Kapata, John Tembo, Peter Mwaba, Juliet Nabyonga-Orem, Francine Ntoumi, Timothy D McHugh

IJID Reg· March 2025

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Sequential and parallel testing for microbiological confirmation of tuberculosis disease in children in five low-income and middle-income countries: a secondary analysis of the RaPaed-TB study.
Laura Olbrich, Zoe Franckling-Smith, Leyla Larsson, Issa Sabi, Nyanda Elias Ntinginya, Timothy Daniel McHugh

Lancet Infect Dis· February 2025

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Personalized CZA-ATM dosing against an XDR E. coli in liver transplant patients; the application of the in vitro hollow fiber system.
Zahra Sadouki, Emmanuel Q Wey, Satheesh Iype, David Nasralla, Jonathan Potts, Timothy D McHugh

Transpl Infect Dis· February 2025

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Efficient assay for evaluating drug efficacy and synergy against emerging SARS-CoV-2 strains.
Maximillian Woodall, Samuel Ellis, Shengyuan Zhang, Japhette Kembou-Ringert, Kerry-Anne Kite, Timothy D McHugh

Antimicrob Agents Chemother· February 2025

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Safety, bactericidal activity, and pharmacokinetics of the antituberculosis drug candidate BTZ-043 in South Africa (PanACEA-BTZ-043-02): an open-label, dose-expansion, randomised, controlled, phase 1b/2a trial.
Norbert Heinrich, Veronique de Jager, Julia Dreisbach, Petra Gross-Demel, Susanne Schultz, Timothy D McHugh

Lancet Microbe· February 2025

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Exploring New Delhi Metallo Beta Lactamases in Klebsiella pneumoniae and Escherichia coli: genotypic vs. phenotypic insights.
Noor Ul Ain, Linzy Elton, Zahra Sadouki, Timothy D McHugh, Saba Riaz

Ann Clin Microbiol Antimicrob· February 2025

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A pragmatic pipeline for drug resistance and lineage identification in Mycobacterium tuberculosis using whole genome sequencing.
Linzy Elton, Alp Aydin, Neil Stoker, Sylvia Rofael, Letícia Muraro Wildner, Timothy D McHugh

PLOS Glob Public Health· February 2025

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Nanomechanical detection to empower robust monitoring of sepsis and microbial adaptive immune system-mediated proinflammatory disease.
Kessarin Thanapirom, Walid Al-Akkad, Aylin Pelut, Zahra Sadouki, Jemima B Finkel, Timothy D McHugh

Sci Rep· December 2024

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Tracing the transmission of carbapenem-resistant Enterobacterales at the patient: ward environmental nexus.
Linzy Elton, Alan Williams, Shanom Ali, Jelena Heaphy, Vicky Pang, Timothy D McHugh

Ann Clin Microbiol Antimicrob· December 2024

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The role of new dengue vaccines in curtailing the emerging global threat of dengue outbreaks arising from mass gathering sporting and religious events.
Eskild Petersen, Linzy Elton, Najmul Haider, Timothy D McHugh, Osman Dar

Int J Infect Dis· November 2024

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The impact of physiological state and environmental stress on bacterial load estimation methodologies for Mycobacterium tuberculosis.
Arundhati Maitra, Marie Wijk, Hasmik Margaryan, Paolo Denti, Timothy D McHugh

Sci Rep· October 2024

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Clinical application of whole-genome sequencing in the management of extensively drug-resistant tuberculosis: a case report.
Bugwesa Z Katale, Sylvia Rofael, Linzy Elton, Erasto V Mbugi, Stella G Mpagama, Timothy D McHugh

Ann Clin Microbiol Antimicrob· August 2024

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Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood.
Antony M Rapulana, Thabo Mpotje, Omolara O Baiyegunhi, Hlumani Ndlovu, Theresa K Smit, Timothy D McHugh

Front Mol Med· January 2024

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