Publications by authors named "Timothy D O'Connell"

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RBFOX1 Regulates Calcium Signaling and Enhances SERCA2 Translation.
Sadiq Umar, Wuqiang Zhu, Fernando Souza-Neto, Ingrid Bender, Steven C Wu, Timothy D O'Connell

Cells· May 2025

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Myosin relaxation states in skeletal muscle fibers of rats and mice: Effects of sex and adiposity.
Zachery A Roloff, Lien A Phung, Luke A Weyrauch, Philip C Woods, Shawna L McMillin, Timothy D O'Connell

Physiol Rep· April 2025

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A Cell Autonomous Free fatty acid receptor 4 - ChemR23 Signaling Cascade Protects Cardiac Myocytes from Ischemic Injury.
Sara J Puccini, Chastity L Healy, Brian A Harsch, Ahmed R Ahmed, Gregory C Shearer, Timothy D O'Connell

bioRxiv· January 2025

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Eicosapentaenoic acid and Arachidonic acid Protection Against Left Ventricle Pathology: the Multi-Ethnic Study of Atherosclerosis.
Gregory C Shearer, Robert C Block, Shue Huang, Linxi Liu, David M Herrington, Timothy D O'Connell

medRxiv· June 2024

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Profibrotic VEGFR3-Dependent Lymphatic Vessel Growth in Autoimmune Valvular Carditis.
Victoria Osinski, Amritha Yellamilli, Maria M Firulyova, Michael J Zhang, Alyssa L Peck, Timothy D O'Connell

Arterioscler Thromb Vasc Biol· April 2024

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Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy.
Michael J Zhang, Sergey Karachenets, Dylan J Gyberg, Sara Puccini, Chastity L Healy, Timothy D O'Connell

bioRxiv· April 2024

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Atrial Myopathy Quantified by Speckle-tracking Echocardiography in Mice.
Michael J Zhang, Dylan J Gyberg, Chastity L Healy, Naixin Zhang, Hong Liu, Timothy D O'Connell

Circ Cardiovasc Imaging· October 2023

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Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term.
Hector Chapoy Villanueva, Jae Hwi Sung, Jackie A Stevens, Michael J Zhang, Peyton M Nelson, Timothy D O'Connell

J Mol Cell Cardiol· August 2023

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Genome-wide association study of Red Blood Cell fatty acids in the Women's Health Initiative Memory Study.
Jason Westra, Carmen Annevelink, Tonya Orchard, Lifang Hou, William S Harris, Timothy D O'Connell

Prostaglandins Leukot Essent Fatty Acids· July 2023

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FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome.
Naixin Zhang, Brian Harsch, Michael J Zhang, Dylan J Gyberg, Jackie A Stevens, Timothy D O'Connell

J Lipid Res· June 2023

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Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.
Chathurika Henpita, Rajesh Vyas, Chastity L Healy, Tra L Kieu, Aditi U Gurkar, Timothy D O'Connell

Aging Cell· April 2023

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Signaling through Free Fatty Acid Receptor 4 Attenuates Cardiometabolic Disease.
Timothy D O'Connell, Katherine A Murphy, Naixin Zhang, Sara J Puccini, Chastity L Healy

Physiology (Bethesda)· November 2022

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Comment on "Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice".
Jennifer L Brown, Katherine A Murphy, Timothy D O'Connell, Sylvain E Lesné

J Immunol· October 2022

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Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases.
Jeremy R Egbert, Tracy F Uliasz, Katie M Lowther, Deborah Kaback, Brandon M Wagner, Timothy D O'Connell

Front Mol Neurosci· October 2022

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Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload.
Katherine A Murphy, Brian A Harsch, Chastity L Healy, Sonal S Joshi, Shue Huang, Timothy D O'Connell

Cardiovasc Res· March 2022

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Guanylyl cyclase-A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice.
Brandon M Wagner, Jerid W Robinson, Chastity L Healy, Madeline Gauthier, Deborah M Dickey, Timothy D O'Connell

FASEB J· January 2022

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Murine Ischemia Reperfusion Without Endotracheal Intubation or Ventilation: A Tutorial.
Michael J Zhang, Sergey Karachenets, Chastity L Healy, Timothy D O'Connell

JACC Basic Transl Sci· July 2021

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Mechanistic insights into cardiovascular protection for omega-3 fatty acids and their bioactive lipid metabolites.
Timothy D O'Connell, Richard Preston Mason, Matthew J Budoff, Ann Marie Navar, Gregory C Shearer

Eur Heart J Suppl· October 2020

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Predicting Risk for Incident Heart Failure With Omega-3 Fatty Acids: From MESA.
Robert C Block, Linxi Liu, David M Herrington, Shue Huang, Michael Y Tsai, Timothy D O'Connell

JACC Heart Fail· August 2019

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ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes.
Erika F Dahl, Steven C Wu, Chastity L Healy, Jocelyn Perry, Timothy D O'Connell

J Mol Cell Cardiol· February 2019

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Subcellular compartmentalization of proximal Gα-receptor signaling produces unique hypertrophic phenotypes in adult cardiac myocytes.
Erika F Dahl, Steven C Wu, Chastity L Healy, Brian A Harsch, Gregory C Shearer, Timothy D O'Connell

J Biol Chem· June 2018

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ω3-Polyunsaturated fatty acids for heart failure: Effects of dose on efficacy and novel signaling through free fatty acid receptor 4.
Timothy D O'Connell, Robert C Block, Shue P Huang, Gregory C Shearer

J Mol Cell Cardiol· February 2017

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With or Without Langendorff: A New Method for Adult Myocyte Isolation to Be Tested With Time.
Xiongwen Chen, Timothy D O'Connell, Yang K Xiang

Circ Res· September 2016

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EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4.
Julie A Eclov, Qingwen Qian, Rebecca Redetzke, Quanhai Chen, Steven C Wu, Timothy D O'Connell

J Lipid Res· December 2015

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Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast.
Liying Zhang, Jing Guo, Pengyuan Zhang, Qiang Xiong, Steven C Wu, Timothy D O'Connell

Circ Heart Fail· January 2015

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