Publications by authors named "Timothy J Bergmann"

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Allosteric Modulation of GCase Enhances Lysosomal Activity and Reduces ER Stress in GCase-Related Disorders.
Ilaria Fregno, Natalia Pérez-Carmona, Mikhail Rudinskiy, Tatiana Soldà, Timothy J Bergmann

Int J Mol Sci· May 2025

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Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors.
Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann

PLoS One· December 2023

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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments.
Diego Morone, Alessandro Marazza, Timothy J Bergmann, Maurizio Molinari

Mol Biol Cell· July 2020

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Three branches to rule them all? UPR signalling in response to chemically versus misfolded proteins-induced ER stress.
Timothy J Bergmann, Maurizio Molinari

Biol Cell· September 2018

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ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport.
Ilaria Fregno, Elisa Fasana, Timothy J Bergmann, Andrea Raimondi, Marisa Loi

EMBO J· September 2018

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Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides.
Timothy J Bergmann, Ilaria Fregno, Fiorenza Fumagalli, Andrea Rinaldi, Francesco Bertoni

J Biol Chem· April 2018

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Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?
Timothy J Bergmann, Fiorenza Fumagalli, Marisa Loi, Maurizio Molinari

Mol Cell Oncol· January 2017

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Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.
Fiorenza Fumagalli, Julia Noack, Timothy J Bergmann, Eduardo Cebollero, Giorgia Brambilla Pisoni

Nat Cell Biol· December 2016

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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.
Fiorenza Fumagalli, Julia Noack, Timothy J Bergmann, Eduardo Cebollero, Giorgia Brambilla Pisoni

Nat Cell Biol· November 2016

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